日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

EGFR amplification and PI3K pathway mutations identify a subset of breast cancers that synergistically respond to EGFR and PI3K inhibition

EGFR扩增和PI3K通路突变可识别出一部分对EGFR和PI3K抑制剂具有协同反应的乳腺癌亚群。

David J Wisniewski,Donna Voeller,Yonit A Addissie,Sachin Kumar Deshmukh,Sharon Wu,Maryam B Lustberg,Darawalee Wangsa,Danny Wangsa,Kerstin Heselmeyer-Haddad,Yoshimi Endo Greer,George W Sledge,Stanley Lipkowitz

TRAIL induces cytokine production via the NFkB2 pathway promoting neutrophil chemotaxis and neutrophil-mediated immune-suppression in triple negative breast cancer cells

TRAIL通过NF-κB2通路诱导细胞因子产生,促进中性粒细胞趋化和中性粒细胞介导的免疫抑制,从而增强三阴性乳腺癌细胞的免疫活性。

Kundu, Manjari; Greer, Yoshimi E; Lobanov, Alexei; Ridnour, Lisa; Donahue, Renee N; Ng, Yeap; Ratnayake, Shashi; White, Karley; Voeller, Donna; Weltz, Sarah; Chen, Qingrong; Lockett, Stephen J; Cam, Maggie; Meerzaman, Daoud; Wink, David A; Weigert, Roberto; Lipkowitz, Stanley

Targeting metabolic vulnerability by combining NAMPT inhibitors and disulfiram for treatment of recurrent ovarian cancer

通过联合使用NAMPT抑制剂和双硫仑来靶向代谢脆弱性,治疗复发性卵巢癌

Kei Kudo ,Yoshimi Endo Greer ,Daniel R Crooks ,Ye Yang ,Jeffrey R Brender ,Teruhiko Yoshida ,Brittney S Harrington ,Rahul Kamdar ,Soumya Korrapati ,Yusuke Shibuya ,Leah Henegar ,Jeffrey Kopp ,Takeo Fujii ,Stanley Lipkowitz ,Christina M Annunziata

Proteogenomic characterization of invasive breast tumors in young women

年轻女性浸润性乳腺肿瘤的蛋白质基因组学特征分析

Raj-Kumar, Praveen-Kumar; Liu, Jianfang; Soltis, Anthony R; Bateman, Nicholas W; Chen, Qingrong; Sturtz, Lori A; Deyarmin, Brenda; Pierobon, Mariaelena; Abulez, Tamara A; Praveen-Kumar, Anupama; Zhang, Xijun; Nguyen, Trinh; Yan, Chunhua; Hu, Ying; Guion, Kate; Hooke, Jeffrey A; Kovatich, Albert J; Fantacone-Campbell, Leigh; Mostoller, Brad; Kvecher, Leonid; Somiari, Stella; Steeg, Patricia S; Rajagopal, Padma Sheila; Darcy, Kathleen M; Lee, Jerry S H; Dalgard, Clifton L; Conrads, Thomas P; Petricoin, Emanuel F; Meerzaman, Daoud; Wilkerson, Matthew D; Lin, Xiaoying; Shriver, Craig D; Lipkowitz, Stanley; Hu, Hai

US cancer deaths prevented due to survival improvements stratified by extent of disease, 2010-2019

2010-2019年美国因生存率提高而避免的癌症死亡人数(按疾病程度分层)

Shiels, Meredith S; Freedman, Neal D; Haque, Anika T; Berrington de González, Amy; Lipkowitz, Stanley; Lowy, Douglas R; Pfeiffer, Ruth M

Elevated tumor NOS2/COX2 promotes immunosuppressive phenotypes associated with poor survival in ER- breast cancer

肿瘤NOS2/COX2水平升高会促进与ER阴性乳腺癌患者预后不良相关的免疫抑制表型。

Ridnour, Lisa A; Cheng, Robert Ys; Heinz, William F; Pore, Milind; Gonzalez, Ana L; Femino, Elise L; Moffat, Rebecca L; Wink, Adelaide L; Imtiaz, Fatima; Coutinho, Leandro L; Butcher, Donna; Edmondson, Elijah F; Rangel, M Cristina; Wong, Stephen Tc; Lipkowitz, Stanley; Glynn, Sharon A; Vitek, Michael P; McVicar, Daniel W; Li, Xiaoxian; Anderson, Stephen K; Paolocci, Nazareno; Hewitt, Stephen M; Ambs, Stefan; Billiar, Timothy R; Chang, Jenny C; Lockett, Stephen J; Wink, David A

Uric Acid Trajectories and CKD Progression in the African American Study of Kidney Disease and Hypertension

非洲裔美国人肾脏疾病和高血压研究中尿酸变化轨迹与慢性肾脏病进展的关系

Lee, Yoojin; Lipkowitz, Michael S; Kopp, Jeffrey B; Winkler, Cheryl A; Cho, Sung Kweon

Revisiting surrogacy of pathological complete response for long-term survival in triple-negative breast cancer

重新审视病理完全缓解作为三阴性乳腺癌长期生存的替代指标

Yoshino, Toru; Zhang, Zao; Sato, Ryota; Lipkowitz, Stanley; Fujii, Takeo

A CSF-1R inhibitor both prevents and treats triple-negative breast cancer brain metastases in hematogenous preclinical models.

CSF-1R 抑制剂在血液传播的临床前模型中既能预防又能治疗三阴性乳腺癌脑转移

Zhang Wei, Rahman Samiur, Wu Alex M L, Isanogle Kristine, Robinson Christina, Kumar Dinesh, Khan Imran, Wei Debbie, Zimmer Alexandra S, Fujii Takeo, Difilippantonio Simone, Lipkowitz Stanley, Steeg Patricia

A Phase II Pilot Study of Anti-PD-L1, Durvalumab, and a PARP Inhibitor, Olaparib in Patients With Metastatic Triple-Negative Breast Cancer With or Without Germline BRCA Mutation.

一项针对伴或不伴有生殖系 BRCA 突变的转移性三阴性乳腺癌患者的 II 期试点研究,评估抗 PD-L1 药物 Durvalumab 和 PARP 抑制剂 Olaparib 的疗效。

Fujii Takeo, Cimino-Mathews Ashley, Lipkowitz Stanley, Lee Min-Jung, Nair Jayakumar, Solarz Britanny Brooke, Zimmer Alexandra, Redd Bernadette, Levy Elliot B, Rastogi Shraddha, Sato Nahoko, McCoy Ann, Steinberg Seth M, Lee Jung-Min