日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability

全基因组 CRISPR 筛选鉴定出野生型和突变型 p53 稳定性的新调节因子

YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jas

Nkd1 functions downstream of Axin2 to attenuate Wnt signaling

Nkd1 在 Axin2 下游发挥作用,减弱 Wnt 信号传导

Ian Bell, Haider Khan, Nathan Stutt, Matthew Horn, Teesha Hydzik, Whitney Lum, Victoria Rea, Emma Clapham, Lisa Hoeg, Terence J Van Raay

NFATC2IP is a mediator of SUMO-dependent genome integrity

NFATC2IP 是 SUMO 依赖基因组完整性的介质

Tiffany Cho, Lisa Hoeg, Dheva Setiaputra, Daniel Durocher

Genome-scale mapping of DNA damage suppressors through phenotypic CRISPR-Cas9 screens

通过表型 CRISPR-Cas9 筛选对 DNA 损伤抑制因子进行基因组规模映射

Yichao Zhao, Daniel Tabet, Diana Rubio Contreras, Linjiang Lao, Arne Nedergaard Kousholt, Jochen Weile, Henrique Melo, Lisa Hoeg, Sumin Feng, Atina G Coté, Zhen-Yuan Lin, Dheva Setiaputra, Jos Jonkers, Anne-Claude Gingras, Fernando Gómez Herreros, Frederick P Roth, Daniel Durocher

An AlphaFold2 map of the 53BP1 pathway identifies a direct SHLD3-RIF1 interaction critical for shieldin activity

53BP1 通路的 AlphaFold2 图谱确定了对 shieldin 活性至关重要的直接 SHLD3-RIF1 相互作用

Chérine Sifri, Lisa Hoeg, Daniel Durocher, Dheva Setiaputra