日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Activation of goblet-cell stress sensor IRE1β is controlled by the mucin chaperone AGR2

杯状细胞应激传感器 IRE1β 的激活受粘蛋白伴侣 AGR2 控制

Eva Cloots, Phaedra Guilbert, Mathias Provost, Lisa Neidhardt, Evelien Van de Velde, Farzaneh Fayazpour, Delphine De Sutter, Savvas N Savvides, Sven Eyckerman #, Sophie Janssens #

The IRE1β-mediated unfolded protein response is repressed by the chaperone AGR2 in mucin producing cells

在粘蛋白产生细胞中,IRE1β 介导的未折叠蛋白反应受到伴侣 AGR2 的抑制

Lisa Neidhardt, Eva Cloots, Natalie Friemel, Caroline A M Weiss, Heather P Harding, Stephen H McLaughlin, Sophie Janssens, David Ron

An oligomeric state-dependent switch in the ER enzyme FICD regulates AMPylation and deAMPylation of BiP

ER 酶 FICD 中的寡聚状态依赖性开关调节 BiP 的 AMPylation 和 deAMPylation

Luke A Perera, Claudia Rato, Yahui Yan, Lisa Neidhardt, Stephen H McLaughlin, Randy J Read, Steffen Preissler, David Ron

Unstructured regions in IRE1α specify BiP-mediated destabilisation of the luminal domain dimer and repression of the UPR

IRE1α中的非结构化区域指定BiP介导的腔内域二聚体的不稳定和UPR的抑制

Niko Amin-Wetzel #, Lisa Neidhardt #, Yahui Yan, Matthias P Mayer, David Ron