日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Targeting the Membrane-Embedded Rhomboid Protease GlpG: A Multimodal Strategy for Inhibitor Discovery and Mechanistic Insight

靶向膜内菱形蛋白酶GlpG：一种用于抑制剂发现和机制研究的多模式策略

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.202514067
Bohg, Claudia; Dubanych, Yurii; Kosteletos, Spyridon; Xiao, Taoran; Neuenschwander, Martin; Utesch, Tillmann; Lisurek, Michael; Öster, Carl; Oder, Andreas; Seyffarth, Carola; Bach, Kathrin; Leone, Denise-Liù Gracias; Filandr, František; Wegert, Marc; Lange, Sascha; Sawczyc, Henry; von Kries, Jens Peter; Hackenberger, Christian P R; Specker, Edgar; Sun, Han; Stříšovský, Kvido; Lange, Adam
发表日期：2026
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Modular Vinyl Phosphonamidates for Cysteine-Directed Protein Targeting

用于半胱氨酸导向蛋白靶向的模块化乙烯基膦酰胺

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.5c22349
Stieger, Christian E; Völkel, Charlotte; Bertelsen, Mathias B; Lisurek, Michael; Arafiles, Jan Vincent V; Franke, Jonathan; Crocker, Leander; Schuppe, Karl; Lim, Yunjae; Groneberg, Christiane; Christmann, Mathias; Sun, Han; Hackenberger, Christian P R
发表日期：2026
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Selectivity and Safety Characterization of a Xanthine-Imidazothiazole Lead Structure: a Novel Tryptophan Hydroxylase Inhibitor of Peripheral Serotonin Synthesis

黄嘌呤-咪唑并噻唑先导化合物的选择性和安全性表征：一种新型外周血清素合成色氨酸羟化酶抑制剂

期刊:ACS Pharmacology and Translational Science
影响因子:
doi:10.1021/acsptsci.5c00043
Wesolowski, Radoslaw; Schütz, Anja; Lisurek, Michael; Nazaré, Marc; Heinemann, Udo; Pleimes, Dirk; Bader, Michael; Specker, Edgar
发表日期：2025
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The opening dynamics of the lateral gate regulates the activity of rhomboid proteases

侧门的开启动态调节菱形蛋白酶的活性

期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.adh3858
Bohg, Claudia; Öster, Carl; Türkaydin, Berke; Lisurek, Michael; Sanchez-Carranza, Pascal; Lange, Sascha; Utesch, Tillmann; Sun, Han; Lange, Adam
发表日期：2023
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Sulfonated red and far-red rhodamines to visualize SNAP- and Halo-tagged cell surface proteins

使用磺化红色和远红色罗丹明来可视化SNAP和Halo标记的细胞表面蛋白

期刊:Organic & Biomolecular Chemistry
影响因子:2.9
doi:10.1039/d1ob02216d.
Ramona Birke ,Julia Ast ,Dorien A Roosen ,Joon Lee ,Kilian Roßmann ,Christiane Huhn ,Bettina Mathes ,Michael Lisurek ,David Bushiri ,Han Sun ,Ben Jones ,Martin Lehmann ,Joshua Levitz ,Volker Haucke ,David J Hodson ,Johannes Broichhagen
HAL
发表日期：2022
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The transcription factor STAT5 catalyzes Mannich ligation reactions yielding inhibitors of leukemic cell proliferation

转录因子 STAT5 催化 Mannich 连接反应，产生白血病细胞增殖抑制剂

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-018-07923-2
Ee Lin Wong, Eric Nawrotzky, Christoph Arkona, Boo Geun Kim, Samuel Beligny, Xinning Wang, Stefan Wagner, Michael Lisurek, Dirk Carstanjen, Jörg Rademann
肿瘤
白血病
其它细胞
WB
发表日期：2019
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Probing the Interactions of Sulfur-Containing Histidine Compounds with Human Gamma-Glutamyl Transpeptidase

探究含硫组氨酸化合物与人γ-谷氨酰转肽酶的相互作用

期刊:Marine Drugs
影响因子:5.4
doi:10.3390/md17120650
Milito, Alfonsina; Brancaccio, Mariarita; Lisurek, Michael; Masullo, Mariorosario; Palumbo, Anna; Castellano, Immacolata
Human
发表日期：2019
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Sensitized detection of inhibitory fragments and iterative development of non-peptidic protease inhibitors by dynamic ligation screening

通过动态连接筛选实现抑制性片段的灵敏检测和非肽类蛋白酶抑制剂的迭代开发

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.200704594
Schmidt, Marco Florian; Isidro-Llobet, Albert; Lisurek, Michael; El-Dahshan, Adeeb; Tan, Jinzhi; Hilgenfeld, Rolf; Rademann, Jörg
发表日期：2008
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