日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

mTOR-driven autophagy suppression defines metabolic vulnerability in CDK4/6 inhibitor-resistant HR(+)/HER2(-) breast cancer.

mTOR 驱动的自噬抑制定义了 CDK4/6 抑制剂耐药的 HR(+)/HER2(-) 乳腺癌的代谢脆弱性。

期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-026-08496-5
von Wichert Luise, Stroh Alina, Witt Marie, Wanzel Michael, Mernberger Marco, Griewing Sebastian, Wündisch Thomas, Pfitzner Berit M, Teply-Szymanski Julia, Litmeyer Anne-Sophie, Denkert Carsten, Wagner Uwe, Stiewe Thorsten, Gremke Niklas
乳腺癌
代谢
MTOR
CDK4
HER2
Autophagy
mTOR
自噬
发表日期：2026
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Targeting PI3K inhibitor resistance in breast cancer with metabolic drugs.

利用代谢药物靶向治疗乳腺癌中的PI3K抑制剂耐药性

期刊:Signal Transduction and Targeted Therapy
影响因子:52.7
doi:10.1038/s41392-025-02180-4
Gremke Niklas, Besong Isabelle, Stroh Alina, von Wichert Luise, Witt Marie, Elmshäuser Sabrina, Wanzel Michael, Fromm Martin F, Taudte R Verena, Schmatloch Sabine, Karn Thomas, Reinisch Mattea, Hirmas Nader, Loibl Sibylle, Wündisch Thomas, Litmeyer Anne-Sophie, Jank Paul, Denkert Carsten, Griewing Sebastian, Wagner Uwe, Stiewe Thorsten
代谢
乳腺癌
PI3K/Akt
肿瘤免疫
发表日期：2025
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DLL3 Expression in Neuroendocrine Carcinomas and Neuroendocrine Tumours: Insights From a Multicentric Cohort of 1294 Pulmonary and Extrapulmonary Neuroendocrine Neoplasms

DLL3在神经内分泌癌和神经内分泌肿瘤中的表达：来自1294例肺内和肺外神经内分泌肿瘤多中心队列研究的启示

期刊:Endocrine Pathology
影响因子:14.7
doi:10.1007/s12022-025-09854-3
Schmitt, Maxime; Bohnenberger, Hanibal; Bartsch, Detlef Klaus; Wagner, Daniel-Christoph; Litmeyer, Anne-Sophie; Grass, Albert; Rinke, Anja; Koch, Christine; Kremer, Marcus; Evert, Matthias; Märkl, Bruno; Quaas, Alexander; Eckstein, Markus; Steinestel, Konrad; Denkert, Carsten; Steiger, Katja; Klöppel, Günter; Kasajima, Atsuko; Tschurtschenthaler, Markus; Foersch, Sebastian; Jesinghaus, Moritz
肿瘤
DLL3
肿瘤免疫
发表日期：2025
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Effects of pregnancy on breast cancer immunology: immune biomarker and TIL quantification

妊娠对乳腺癌免疫学的影响：免疫生物标志物和肿瘤浸润淋巴细胞定量

期刊:NPJ Breast Cancer
影响因子:7.6
doi:10.1038/s41523-025-00758-3
Galas, Kristin; Gleitsmann, Moritz; Rey, Julia; Solbach, Christine; Witzel, Isabell; Karn, Thomas; Schmatloch, Sabine; Schem, Christian; Schneeweis, Andreas; Sinn, Bruno; Fehm, Tanja; Denkert, Carsten; Fasching, Peter; Litmeyer, Anne-Sophie; Marmé, Frederik; Jank, Paul; Müller, Volkmar; Seiler, Sabine; Stickeler, Elmar; Ortmann, Olaf; van Mackelenbergh, Marion; Nekljudova, Valentina; Holtschmidt, Johannes; Loibl, Sibylle
肿瘤
肿瘤免疫
乳腺癌
细胞生物学
免疫/内分泌
发表日期：2025
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Stroma areactive invasion front areas (SARIFA) in 1,298 pT3/pT4 colorectal cancers: A strong prognostic parameter complementing established morphological criteria

1298例pT3/pT4期结直肠癌的间质反应性侵袭前沿区域（SARIFA）：一项强有力的预后参数，可作为现有形态学标准的补充

期刊:Histopathology
影响因子:4.1
doi:10.1111/his.15501
Foersch, Sebastian; Harb, Nuwar; Litmeyer, Anne-Sophie; Roth, Wilfried; Breus, Irina; Schraml, Johannes; Weiß, Annika; Steiger, Katja; Teply-Szymanski, Julia; Bartsch, Detlef K; Denkert, Carsten; Schmitt, Maxime; Jesinghaus, Moritz
肿瘤
肠癌
肿瘤免疫
发表日期：2025
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TROP2 in colorectal carcinoma: associations with histopathology, molecular phenotype, and patient prognosis

TROP2在结直肠癌中的表达：与组织病理学、分子表型和患者预后的关系

期刊:Journal of Pathology Clinical Research
影响因子:3.7
doi:10.1002/2056-4538.12394
Foersch, Sebastian; Schmitt, Maxime; Litmeyer, Anne-Sophie; Tschurtschenthaler, Markus; Gress, Thomas; Bartsch, Detlef K; Pfarr, Nicole; Steiger, Katja; Denkert, Carsten; Jesinghaus, Moritz
肿瘤
肠癌
肿瘤免疫
发表日期：2024
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High expression of insulinoma-associated protein 1 (INSM1) distinguishes colorectal mixed and pure neuroendocrine carcinomas from conventional adenocarcinomas with diffuse expression of synaptophysin

胰岛素瘤相关蛋白1（INSM1）的高表达可将结直肠混合型和纯神经内分泌癌与突触素弥漫表达的传统腺癌区分开来。

期刊:Journal of Pathology Clinical Research
影响因子:3.7
doi:10.1002/cjp2.339
Litmeyer, Anne-Sophie; Konukiewitz, Björn; Kasajima, Atsuko; Foersch, Sebastian; Schicktanz, Felix; Schmitt, Maxime; Kellers, Franziska; Grass, Albert; Jank, Paul; Lehman, Bettina; Gress, Thomas M; Rinke, Anja; Bartsch, Detlef K; Denkert, Carsten; Weichert, Wilko; Klöppel, Günter; Jesinghaus, Moritz
肿瘤
肿瘤免疫
INSM1
神经科学
免疫/内分泌
发表日期：2023
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pT3 colorectal cancer revisited: a multicentric study on the histological depth of invasion in more than 1000 pT3 carcinomas-proposal for a new pT3a/pT3b subclassification

重新审视pT3结直肠癌：一项针对1000多例pT3癌组织学浸润深度的多中心研究——提出新的pT3a/pT3b亚分类

期刊:British Journal of Cancer
影响因子:6.8
doi:10.1038/s41416-022-01889-1
Foersch, Sebastian; Lang-Schwarz, Corinna; Eckstein, Markus; Geppert, Carol; Schmitt, Maxime; Konukiewitz, Björn; Groll, Tanja; Schicktanz, Felix; Engel, Jutta; Gleitsmann, Moritz; Westhoff, Christina C; Frickel, Nadine; Litmeyer, Anne-Sophie; Grass, Albert; Jank, Paul; Lange, Sebastian; Tschurtschenthaler, Markus; Wilhelm, Dirk; Roth, Wilfried; Vieth, Michael; Denkert, Carsten; Nagtegaal, Iris; Weichert, Wilko; Jesinghaus, Moritz
肠癌
肿瘤
肿瘤免疫
发表日期：2022
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