日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The MDM2/MDMX/p53 axis in the adaptive stress response

适应性应激反应中的MDM2/MDMX/p53轴

Wang, Bing; Rasmussen-Ivey, Cody; Little, John B; Yuan, Zhi-Min

Coordination of the Ser2056 and Thr2609 Clusters of DNA-PKcs in Regulating Gamma Rays and Extremely Low Fluencies of Alpha-Particle Irradiation to G(0)/G(1) Phase Cells

DNA-PKcs Ser2056 和 Thr2609 簇的协调作用在调节 G(0)/G(1) 期细胞受到的伽马射线和极低剂量 α 粒子照射中的作用

Nagasawa, Hatsumi; Lin, Yu-Fen; Kato, Takamitsu A; Brogan, John R; Shih, Hung-Ying; Kurimasa, Akihiro; Bedford, Joel S; Chen, Benjamin P C; Little, John B

UXT, a novel MDMX-binding protein, promotes glycolysis by mitigating p53-mediated restriction of NF-κB activity

UXT是一种新型的MDMX结合蛋白,它通过减轻p53介导的NF-κB活性抑制来促进糖酵解。

Qi, Min; Ganapathy, Suthakar; Zeng, Weiqi; Zhang, Jianglin; Little, John B; Yuan, Zhi-Min

A low-dose arsenic-induced p53 protein-mediated metabolic mechanism of radiotherapy protection.

低剂量砷诱导的 p53 蛋白介导的放射治疗保护代谢机制

Ganapathy Suthakar, Xiao Shaowen, Yang Mei, Qi Min, Choi Doo Eun, Ha Chul S, Little John B, Yuan Zhi-Min

Differential radiosensitivity phenotypes of DNA-PKcs mutations affecting NHEJ and HRR systems following irradiation with gamma-rays or very low fluences of alpha particles

γ射线或极低剂量α粒子照射后,影响NHEJ和HRR系统的DNA-PKcs突变表现出不同的放射敏感性表型。

Lin, Yu-Fen; Nagasawa, Hatsumi; Little, John B; Kato, Takamitsu A; Shih, Hung-Ying; Xie, Xian-Jin; Wilson, Paul F Jr; Brogan, John R; Kurimasa, Akihiro; Chen, David J; Bedford, Joel S; Chen, Benjamin P C

Differential role of DNA-PKcs phosphorylations and kinase activity in radiosensitivity and chromosomal instability

DNA-PKcs磷酸化和激酶活性在放射敏感性和染色体不稳定性中的差异性作用

Nagasawa, Hatsumi; Little, John B; Lin, Yu-Fen; So, Sairei; Kurimasa, Akihiro; Peng, Yuanlin; Brogan, John R; Chen, David J; Bedford, Joel S; Chen, Benjamin P C

The role of gap junction communication and oxidative stress in the propagation of toxic effects among high-dose α-particle-irradiated human cells.

高剂量α粒子照射的人类细胞中,间隙连接通讯和氧化应激在毒性效应传播中的作用

Autsavapromporn Narongchai, de Toledo Sonia M, Little John B, Jay-Gerin Jean-Paul, Harris Andrew L, Azzam Edouard I

Tumor response to radiotherapy is dependent on genotype-associated mechanisms in vitro and in vivo

肿瘤对放射疗法的反应取决于体外和体内的基因型相关机制。

Williams, Jerry R; Zhang, Yonggang; Zhou, Haoming; Gridley, Daila S; Koch, Cameron J; Dicello, John F; Slater, James M; Little, John B

Response to the Letter by Colin Seymour and Carmel Mothersill

科林·西摩和卡梅尔·莫瑟希尔对这封信的回应

Azzam, Edouard I; Little, John B