日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A metagenomic library cloning strategy that promotes high-level expression of captured genes to enable efficient functional screening.

一种促进捕获基因高水平表达的宏基因组文库克隆策略,可实现高效的功能筛选

Rich Michelle H, Sharrock Abigail V, Mulligan Timothy S, Matthews Frazer, Brown Alistair S, Lee-Harwood Hannah R, Williams Elsie M, Copp Janine N, Little Rory F, Francis Jenni J B, Horvat Claire N, Stevenson Luke J, Owen Jeremy G, Saxena Meera T, Mumm Jeff S, Ackerley David F

A metagenomic library cloning strategy that promotes high-level expression of captured genes to enable efficient functional screening

一种促进捕获基因高水平表达的宏基因组文库克隆策略,可实现高效的功能筛选。

Rich, Michelle H; Sharrock, Abigail V; Mulligan, Timothy S; Matthews, Frazer; Brown, Alistair S; Lee-Harwood, Hannah R; Williams, Elsie M; Copp, Janine N; Little, Rory F; Francis, Jenni Jb; Horvat, Claire N; Stevenson, Luke J; Owen, Jeremy G; Saxena, Meera T; Mumm, Jeff S; Ackerley, David F

Insect-Associated Bacteria Assemble the Antifungal Butenolide Gladiofungin by Non-Canonical Polyketide Chain Termination

与昆虫相关的细菌通过非经典聚酮链终止反应组装抗真菌丁烯内酯类化合物唐菖蒲素

Niehs, Sarah P; Kumpfmüller, Jana; Dose, Benjamin; Little, Rory F; Ishida, Keishi; Flórez, Laura V; Kaltenpoth, Martin; Hertweck, Christian

Intracellular complexities of acquiring a new enzymatic function revealed by mass-randomisation of active-site residues

通过活性位点残基的质量随机化揭示获得新的酶功能的细胞内复杂性

Hall, Kelsi R; Robins, Katherine J; Williams, Elsie M; Rich, Michelle H; Calcott, Mark J; Copp, Janine N; Little, Rory F; Schwörer, Ralf; Evans, Gary B; Patrick, Wayne M; Ackerley, David F

Mechanistic Understanding Enables the Rational Design of Salicylanilide Combination Therapies for Gram-Negative Infections

机制理解有助于合理设计水杨酰苯胺类药物联合疗法治疗革兰氏阴性菌感染

Copp, Janine N; Pletzer, Daniel; Brown, Alistair S; Van der Heijden, Joris; Miton, Charlotte M; Edgar, Rebecca J; Rich, Michelle H; Little, Rory F; Williams, Elsie M; Hancock, Robert E W; Tokuriki, Nobuhiko; Ackerley, David F

The biosynthetic pathway to tetromadurin (SF2487/A80577), a polyether tetronate antibiotic

四氢马杜林(SF2487/A80577)是一种聚醚四酮酸酯类抗生素,其生物合成途径如下:

Little, Rory F; Samborskyy, Markiyan; Leadlay, Peter F