Benzo(a)pyrene-caused increased G1-S transition requires the activation of c-Jun through p53-dependent PI-3K/Akt/ERK pathway in human embryo lung fibroblasts.
苯并[a]芘引起的 G1-S 转换增加需要通过 p53 依赖的 PI-3K/Akt/ERK 通路激活 c-Jun,才能在人类胚胎肺成纤维细胞中发挥作用
期刊:Toxicology Letters
影响因子:2.9
doi:10.1016/j.toxlet.2008.03.012
Jiao Shi, Liu Bingci, Gao Ai, Ye Meng, Jia Xiaowei, Zhang Fengmei, Liu Haifeng, Shi Xianglin, Huang Chuanshu