Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome
设计对恶性疟原虫具有体内口服疗效且对人蛋白酶体具有选择性的蛋白酶体抑制剂
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2107213118
Xie, Stanley C; Metcalfe, Riley D; Mizutani, Hirotake; Puhalovich, Tanya; Hanssen, Eric; Morton, Craig J; Du, Yawei; Dogovski, Con; Huang, Shih-Chung; Ciavarri, Jeffrey; Hales, Paul; Griffin, Robert J; Cohen, Lawrence H; Chuang, Bei-Ching; Wittlin, Sergio; Deni, Ioanna; Yeo, Tomas; Ward, Kurt E; Barry, Daniel C; Liu, Boyin; Gillett, David L; Crespo-Fernandez, Benigno F; Ottilie, Sabine; Mittal, Nimisha; Churchyard, Alisje; Ferguson, Daniel; Aguiar, Anna Caroline C; Guido, Rafael V C; Baum, Jake; Hanson, Kirsten K; Winzeler, Elizabeth A; Gamo, Francisco-Javier; Fidock, David A; Baud, Delphine; Parker, Michael W; Brand, Stephen; Dick, Lawrence R; Griffin, Michael D W; Gould, Alexandra E; Tilley, Leann
