日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Cancer-Associated Fibroblasts Functions as Multifunctional Architects of the Tumor Stroma and Represent Emerging Therapeutic Vulnerabilities

癌症相关成纤维细胞作为肿瘤基质的多功能构建者，代表着新兴的治疗弱点

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202510043
Liu, Rujiao; Su, Lili; Gao, Shuiping; Liu, Wenting; Wang, Hongxia
成纤维细胞
细胞生物学
肿瘤
肿瘤免疫
发表日期：2026
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Transcriptome Landscape of Cancer-Associated Fibroblasts in Human PDAC.

人类胰腺导管腺癌相关成纤维细胞的转录组图谱

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202415196
Tao Mengyu, Liu Wenting, Chen Jianhua, Liu Rujiao, Zou Jianling, Yu Bo, Wang Chenchen, Huang Mingzhu, Chen Qingjian, Zhang Zhe, Chen Zhiyu, Sun Haoyu, Zhou Cheng, Tan Shuguang, Zheng Yuxuan, Wang Hongxia
细胞生物学
Human
肿瘤免疫
发表日期：2025
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A phase 1 trial of APG-1387, an IAP antagonist, with nab-paclitaxel and gemcitabine in patients with refractory metastatic pancreatic cancer

一项针对难治性转移性胰腺癌患者的 I 期临床试验，评估 IAP 拮抗剂 APG-1387 联合白蛋白紫杉醇和吉西他滨的疗效

期刊:Cell Reports Medicine
影响因子:10.6
doi:10.1016/j.xcrm.2025.102364
Shi, Si; Zhang, Jian; Liu, Rujiao; Gao, Shuiping; Xu, Jin; Wang, Wei; Wei, Miaoyan; Li, Jialin; Liu, Chen; Xu, Xiaowu; Pan, Wentao; Tian, Xiaohong; Men, Lichuang; Wang, Hengbang; Liang, Zhiyan; Zhu, Min; Yang, Dajun; Zhai, Yifan; Yu, XianJun
胰腺癌
肿瘤
肿瘤免疫
发表日期：2025
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Correction: Phase 1b study of first-line fuzuloparib combined with modified FOLFIRINOX followed by fuzuloparib maintenance monotherapy in pancreatic adenocarcinoma

更正：一项针对胰腺腺癌的一线治疗方案为氟哌啶醇联合改良FOLFIRINOX方案，随后进行氟哌啶醇维持单药治疗的1b期研究

期刊:BMC Medicine
影响因子:8.3
doi:10.1186/s12916-025-04078-y
Wei, Miaoyan; Liu, Rujiao; Xu, Yunyun; Chen, Xiaobing; Liu, Chao; Bai, Xueli; Zhang, Xiaochen; Gao, Shuiping; Li, Jialin; Sheng, Zhen; Lian, Jianpo; Wang, Wenliang; Zhang, Jian; Shi, Si; Xu, Jin; Yu, Xianjun
肿瘤
肿瘤免疫
发表日期：2025
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Phase 1b study of first-line fuzuloparib combined with modified FOLFIRINOX followed by fuzuloparib maintenance monotherapy in pancreatic adenocarcinoma

一项针对胰腺腺癌的一线治疗方案为：一线使用氟哌啶醇联合改良FOLFIRINOX方案，随后进行氟哌啶醇单药维持治疗。

期刊:BMC Medicine
影响因子:8.3
doi:10.1186/s12916-024-03581-y
Wei, Miaoyan; Liu, Rujiao; Xu, Yunyun; Chen, Xiaobing; Liu, Chao; Bai, Xueli; Zhang, Xiaochen; Gao, Shuiping; Li, Jialin; Sheng, Zhen; Lian, Jianpo; Wang, Wenliang; Zhang, Jian; Shi, Si; Xu, Jin; Yu, Xianjun
肿瘤
肿瘤免疫
发表日期：2024
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Phase I study of A166, an antibody‒drug conjugate in advanced HER2-expressing solid tumours

A166（一种抗体-药物偶联物）治疗晚期HER2表达实体瘤的I期研究

期刊:NPJ Breast Cancer
影响因子:7.6
doi:10.1038/s41523-023-00522-5
Zhang, Jian; Liu, Rujiao; Gao, Shuiping; Li, Wenhua; Chen, Yang; Meng, Yanchun; Liu, Chang; Jin, Wenyue; Wu, Junyan; Wang, Ying; Hao, Yanrong; Yi, Shuli; Qing, Yan; Ge, Junyou; Hu, Xichun
HER2
发表日期：2023
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Corrigendum: Longitudinal Circulating Tumor DNA Profiling in Metastatic Colorectal Cancer During Anti-EGFR Therapy

更正：抗EGFR治疗期间转移性结直肠癌患者的循环肿瘤DNA纵向分析

期刊:Frontiers in Oncology
影响因子:3.3
doi:10.3389/fonc.2022.903586
Yang, Wentao; Zou, Jianling; Li, Ye; Liu, Rujiao; Yan, Zhengqing; Chen, Shiqing; Zhao, Xiaoying; Guo, Weijian; Huang, Mingzhu; Li, Wenhua; Zhu, Xiaodong; Chen, Zhiyu
EGFR
EGF
肿瘤
肠癌
肿瘤免疫
发表日期：2022
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Phase I study of pucotenlimab (HX008), an anti-PD-1 antibody, for patients with advanced solid tumors

一项针对晚期实体瘤患者的抗PD-1抗体pucotenlimab（HX008）的I期研究

期刊:Therapeutic Advances in Medical Oncology
影响因子:4.2
doi:10.1177/17588359211020528
Liu, Rujiao; Li, Wenhua; Meng, Yanchun; Gao, Shuiping; Zhang, Jian; Hu, Xichun
PD-1
发表日期：2021
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Advantage of Next-Generation Sequencing in Dynamic Monitoring of Circulating Tumor DNA over Droplet Digital PCR in Cetuximab Treated Colorectal Cancer Patients

在接受西妥昔单抗治疗的结直肠癌患者中，与液滴数字PCR相比，下一代测序在循环肿瘤DNA动态监测方面具有优势

期刊:Translational Oncology
影响因子:4.1
doi:10.1016/j.tranon.2018.11.015
Zhang, Hangyu; Liu, Rujiao; Yan, Cong; Liu, Lulu; Tong, Zhou; Jiang, Weiqin; Yao, Ming; Fang, Weijia; Chen, Zhiyu
肠癌
肿瘤
肿瘤免疫
发表日期：2019
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The combination of RAD001 and MK-2206 exerts synergistic cytotoxic effects against PTEN mutant gastric cancer cells: involvement of MAPK-dependent autophagic, but not apoptotic cell death pathway.

RAD001 和 MK-2206 的组合对 PTEN 突变胃癌细胞具有协同细胞毒性作用：涉及 MAPK 依赖性自噬，但不涉及凋亡细胞死亡途径

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0085116
Ji Dongmei, Zhang Zhe, Cheng Lei, Chang Jinjia, Wang Shanshan, Zheng Biqiang, Zheng Rongliang, Sun Zuojun, Wang Chenchen, Zhang Zhiqing, Liu Rujiao, Zhang Xiaowei, Liu Xin, Wang Xiaofeng, Li Jin
细胞生物学
胃癌
MAPK/ERK
凋亡
自噬
发表日期：2014
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