APOE-stratified Proteomic and Metabolomic Analysis Reveals Mitochondrial Dysfunction Inflammation and Lipid Dysregulation in Alzheimer's Disease
基于APOE分层的蛋白质组学和代谢组学分析揭示了阿尔茨海默病中的线粒体功能障碍、炎症和脂质代谢紊乱
期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202513872
Li, Fuhai; Chen, Yike; Western, Daniel; Ali, Muhammad; Liu, Menghan; Gong, Katherine; Xu, Ying; Lowery, Joseph; Holtzman, David M; Robins, Chloe; Eicher, John D; Huang, Yen-Ning; Liu, ShiWei; Park, Tamina; Saykin, Andrew J; Nho, Kwangsik; Moqri, Mahdi; Mohs, Richard C; Farinas, Amelia; Moran-Losada, Patricia; Oh, Hamilton Se-Hwee; Wyss-Coray, Tony; Cruchaga, Carlos
炎症
炎症/感染
阿尔茨海默症
Immunology/Inflammation
代谢
APOE
线粒体
