Antiemetic drug fosaprepitant exerts anti-tumor effects against NSCLC by targeting FAK to inhibit AKT and JNK/c-Jun pathways
止吐药福沙匹坦通过靶向FAK抑制AKT和JNK/c-Jun通路，发挥抗非小细胞肺癌的肿瘤作用。
期刊:Acta Pharmacologica Sinica
影响因子:8.4
doi:10.1038/s41401-025-01645-0
Wang, Ying; Shao, Yu-Na; Ma, Chen-Kang; Shu, Chen-Ying; Zhang, Yi-Hua; Lu, Di; Zhang, Hui-Ling; Zhu, Jian-Jie; Zeng, Yuan-Yuan; Li, Jian-Jun; Yan, Zhao-Wei; Liu, Ze-Yi
信号转导
AKT
JNK
细胞生物学
c-Jun
肺癌
FAK
肿瘤
肿瘤免疫
