日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Forsythoside E Alleviates Liver Injury by Targeting PKM2 Tetramerization to Promote Macrophage M2 Polarization

连翘苷E通过靶向PKM2四聚体化促进巨噬细胞M2极化，从而减轻肝损伤

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202514514
Wu, Bingxin; Yu, Xuechun; Li, Yanling; An, Lin; Zhang, Rongrong; Zhang, Rong; Zhang, Fan; Liu, Zhongqiu; Wang, Caiyan
巨噬细胞
巨噬细胞
肝损伤
细胞生物学
毒理研究
免疫/内分泌
发表日期：2026
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Microneedle-based delivery of cell membrane vesicles as IL-17RA decoys for Psoriasis treatment

利用微针递送细胞膜囊泡作为IL-17RA诱饵治疗银屑病

期刊:Journal of Nanobiotechnology
影响因子:12.6
doi:10.1186/s12951-026-04265-w
Tu, Bin; Fang, Weifeng; Liu, Lin; Sun, Yao; Hu, Mei; Asrorov, Akmal; Wang, Zhao; Liu, Ergang; Huang, Yongzhuo; Liu, Zhongqiu; Dai, Weibo
囊泡
细胞生物学
银屑病
IL-17
发表日期：2026
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Schisandrin B Targets PXR to Enhance Bile Acid Metabolism and Alleviate ANIT-Induced Cholestatic Liver Injury via Dual Pathways

五味子素B通过双重途径靶向PXR，增强胆汁酸代谢并减轻ANIT诱导的胆汁淤积性肝损伤

期刊:International Journal of Biological Sciences
影响因子:10
doi:10.7150/ijbs.121475
Zhang, Ying; Lan, Huan; Yu, Xuechun; Zhuo, Lin; Zhao, Bixin; Liu, Fang; An, Lin; Zhang, Fan; Liu, Zhongqiu; Wang, Caiyan
肝损伤
毒理研究
代谢
发表日期：2026
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CD44/POU2F2/BCL9L axis mediates MIF-driven SPP1(+)TAM activation in colorectal cancer metastasis

CD44/POU2F2/BCL9L轴介导MIF驱动的SPP1(+)TAM活化在结直肠癌转移中的作用

期刊:International Journal of Biological Sciences
影响因子:10
doi:10.7150/ijbs.116575
Zhang, Fan; Zhao, Bingquan; Fan, Xueying; Shi, Zhiqiang; Guo, Peilan; Zhang, Haibo; Kwan, Hiu-Yee; Liu, Zhongqiu; Su, Tao
肿瘤
肠癌
T细胞
肿瘤免疫
CD44
MIF
BCL9L
CD4
发表日期：2026
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Structural pharmacology of Chinese medicine: technological breakthroughs in decoding multi-target synergy and precision mechanisms

中药结构药理学：解码多靶点协同作用和精准机制的技术突破

期刊:
影响因子:
doi:10.1007/s44307-026-00095-x
Wang, Caiyan; Li, Yanling; Zhuo, Lin; Xu, Songzhu; Wang, Mengyao; Liu, Zhongqiu
发表日期：2026
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Geniposidic Acid Targeting FXR "S332 and H447" Mediated Conformational Change to Upregulate CYPs and miR-19a-3p to Ameliorate Drug-Induced Liver Injury.

京尼泊苷酸靶向 FXR“S332 和 H447”介导的构象变化，上调 CYP 和 miR-19a-3p，从而改善药物引起的肝损伤

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202409107
Fan Minqi, Xu Yuanhang, Wu Bingxin, Long Jiachan, Liu Caihong, Liang Zuhui, Zhang Rong, Liu Zhongqiu, Wang Caiyan
毒理研究
肝损伤
药物研究
发表日期：2025
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Disruption of the eEF1A1/ARID3A/PKC-δ Complex by Neferine Inhibits Macrophage Glycolytic Reprogramming in Atherosclerosis.

尼非林破坏 eEF1A1/ARID3A/PKC-α 复合物抑制动脉粥样硬化中巨噬细胞的糖酵解重编程

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202416158
Xie Baoping, Tian Li-Wen, Liu Chenxu, Li Jiahua, Tian Xiaoyu, Zhang Rong, Zhang Fan, Liu Zhongqiu, Cheng Yuanyuan
细胞生物学
动脉粥样硬化
巨噬细胞
发表日期：2025
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Elucidation of the biosynthetic pathways of timosaponins reveals the antifungal mechanisms in Anemarrhena asphodeloides

阐明知母皂苷的生物合成途径揭示了知母的抗真菌机制

期刊:Journal of Advanced Research
影响因子:13
doi:10.1016/j.jare.2025.01.049
Fan, Baolian; Ji, Zhongju; Zhu, Min; Chen, Yidu; Liang, Jincai; Li, Yu; Yi, Runxiang; Liu, Chenxu; Wang, Lijun; Shi, Ningwei; Yang, Tingxing; Huang, Ruoshi; Yang, Lu; Ji, Aijia; Liu, Zhongqiu; Duan, Lixin
微生物学
发表日期：2025
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Pharmacological upregulation of macrophage-derived itaconic acid by pubescenoside C attenuated myocardial ischemia-reperfusion injury.

毛蕊花苷 C 通过药理学上调巨噬细胞衍生的衣康酸，减轻了心肌缺血再灌注损伤

期刊:Journal of Advanced Research
影响因子:13
doi:10.1016/j.jare.2024.09.024
Chen Sixuan, Yao Haojie, Lou Yanmei, Wang Huihui, Xie Baoping, Wu Junxuan, Qi Xiaoxiao, Wang Ying, Wu Peng, Zhang Rong, Liu Zhongqiu, Cheng Yuanyuan
细胞生物学
心肌炎
巨噬细胞
发表日期：2025
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Alcaligenes faecalis promotes colitis to colorectal cancer transition through IgA+ B cell suppression and vinculin acetylation

粪产碱杆菌通过抑制IgA+ B细胞和乙酰化黏着斑蛋白促进结肠炎向结直肠癌的转化。

期刊:Gut Microbes
影响因子:11
doi:10.1080/19490976.2025.2473511
Zheng, Jing; Zhou, Chishun; Li, Zizheng; Jin, Xin; Zou, Yihua; Bai, Shasha; Zheng, Huanjin; Ling, Weichao; Zhao, Yiru; Wang, Ying; Zhang, Rong; Liu, Zhongqiu; Lu, Linlin
B细胞
IgA
肿瘤
肠癌
肠炎
表观遗传
肿瘤免疫
乙酰化
细胞生物学
结肠炎
免疫/内分泌
发表日期：2025
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