日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Novel Lipidated Imidazoquinoline TLR7/8 Adjuvants Elicit Influenza-Specific Th1 Immune Responses and Protect Against Heterologous H3N2 Influenza Challenge in Mice

新型脂化咪唑喹啉TLR7/8佐剂可诱导流感特异性Th1免疫反应,并保护小鼠免受异源H3N2流感病毒攻击

Miller, Shannon M; Cybulski, Van; Whitacre, Margaret; Bess, Laura S; Livesay, Mark T; Walsh, Lois; Burkhart, David; Bazin, Hélène G; Evans, Jay T

Optimization of 8-oxoadenines with toll-like-receptor 7 and 8 activity

优化具有 Toll 样受体 7 和 8 活性的 8-氧代腺嘌呤。

Bazin, Hélène G; Bess, Laura S; Livesay, Mark T; Li, Yufeng; Cybulski, Van; Miller, Shannon M; Johnson, David A; Evans, Jay T

Synthetic Toll-like Receptors 7 and 8 Agonists: Structure-Activity Relationship in the Oxoadenine Series.

合成 Toll 样受体 7 和 8 激动剂:氧代腺嘌呤系列的结构-活性关系

Evans Jay T, Bess Laura S, Mwakwari Sandra C, Livesay Mark T, Li Yufeng, Cybulski Van, Johnson David A, Bazin Hélène G

Phospholipidation of TLR7/8-active imidazoquinolines using a tandem phosphoramidite method

利用串联亚磷酰胺法对TLR7/8活性咪唑喹啉进行磷脂化

Bazin, Hélène G; Bess, Laura S; Livesay, Mark T; Mwakwari, Sandra C; Johnson, David A

Characterization of TRIF selectivity in the AGP class of lipid A mimetics: role of secondary lipid chains

脂质A类似物AGP类化合物中TRIF选择性的表征:二级脂质链的作用

Khalaf, Juhienah K; Bowen, William S; Bazin, Hélène G; Ryter, Kendal T; Livesay, Mark T; Ward, Jon R; Evans, Jay T; Johnson, David A

Structural requirements for TLR7-selective signaling by 9-(4-piperidinylalkyl)-8-oxoadenine derivatives

9-(4-哌啶基烷基)-8-氧代腺嘌呤衍生物对TLR7选择性信号传导的结构要求

Bazin, Hélène G; Li, Yufeng; Khalaf, Juhienah K; Mwakwari, Sandra; Livesay, Mark T; Evans, Jay T; Johnson, David A

Synthetic toll-like receptor 4 agonists stimulate innate resistance to infectious challenge

合成的 Toll 样受体 4 激动剂可刺激机体对感染的先天抵抗力

Cluff, Christopher W; Baldridge, Jory R; Stöver, Axel G; Evans, Jay T; Johnson, David A; Lacy, Michael J; Clawson, Valerie G; Yorgensen, Vonnie M; Johnson, Craig L; Livesay, Mark T; Hershberg, Robert M; Persing, David H