日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Multiplexed CRISPR/Cas9 Editing of Tumor Suppressor Genes in the Mouse Endometrium Recapitulates High-Risk Endometrial Carcinoma

利用 CRISPR/Cas9 技术对小鼠子宫内膜中的抑癌基因进行多重编辑，可重现高危子宫内膜癌的发生发展过程。

期刊:Cancer Communications
影响因子:24.9
doi:10.34133/cancomm.0010
Vidal-Sabanés, Maria; Navaridas, Raúl; Bonifaci, Núria; Gay-Rua, Ada; Ortega-Peinado, Damià; Egea, Joaquim; Encinas, Mario; Matias-Guiu, Xavier; Llobet-Navas, David; Dolcet, Xavier
肿瘤
Mouse
子宫内膜癌
肿瘤免疫
发表日期：2026
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miR-424(322)(~)503 impairs colon cancer progression driven by PTEN deficiency

miR-424(322)(~)503 抑制 PTEN 缺陷驱动的结肠癌进展

期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-026-08504-8
Vidal-Sabanés, Maria; Bonifaci, Núria; Navaridas, Raúl; Egea, Joaquim; Encinas, Mario; Rodriguez-Barrueco, Ruth; Silva, Jose M; Matias-Guiu, Xavier; Tarragona, Jordi; Llobet-Navas, David; Dolcet, Xavier
PTEN
肿瘤
肠癌
肿瘤免疫
发表日期：2026
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Endometrial cancer progression driven by PTEN-deficiency requires miR-424(322)(~)503

由 PTEN 缺陷驱动的子宫内膜癌进展需要 miR-424(322)(~)503

期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-025-08022-z
Vidal-Sabanés, Maria; Bonifaci, Núria; Navaridas, Raúl; Egea, Joaquim; Encinas, Mario; Rodriguez-Barrueco, Ruth; Silva, Jose M; Matias-Guiu, Xavier; Llobet-Navas, David; Dolcet, Xavier
PTEN
肿瘤
子宫内膜癌
肿瘤免疫
发表日期：2025
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Dysregulated autophagy in endometriosis: molecular mechanisms, controversies, and clinical implications

子宫内膜异位症中自噬失调：分子机制、争议和临床意义

期刊:Reproductive Biology and Endocrinology
影响因子:4.7
doi:10.1186/s12958-025-01494-w
Tellez-Quijorna, Clara; Juan-Lopez, Ainhoa; Eritja, Nuria; Llobet-Navas, David; Devis-Jauregui, Laura
自噬
发表日期：2025
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Transient and DNA-free in vivo CRISPR/Cas9 genome editing for flexible modeling of endometrial carcinogenesis

利用瞬时且不含DNA的体内CRISPR/Cas9基因组编辑技术，可灵活模拟子宫内膜癌变过程。

期刊:Cancer Communications
影响因子:24.9
doi:10.1002/cac2.12409
Navaridas, Raúl; Vidal-Sabanés, Maria; Ruiz-Mitjana, Anna; Perramon-Güell, Aida; Megino-Luque, Cristina; Llobet-Navas, David; Matias-Guiu, Xavier; Egea, Joaquim; Encinas, Mario; Bardia, Lídia; Colombelli, Julien; Dolcet, Xavier
肿瘤
子宫内膜癌
肿瘤免疫
发表日期：2023
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Structural disruption of BAF chromatin remodeller impairs neuroblastoma metastasis by reverting an invasiveness epigenomic program

BAF染色质重塑因子的结构破坏通过逆转侵袭性表观基因组程序来抑制神经母细胞瘤转移。

期刊:Molecular Cancer
影响因子:33.9
doi:10.1186/s12943-022-01643-4
Jiménez, Carlos; Antonelli, Roberta; Nadal-Ribelles, Mariona; Devis-Jauregui, Laura; Latorre, Pablo; Solé, Carme; Masanas, Marc; Molero-Valenzuela, Adrià; Soriano, Aroa; Sánchez de Toledo, Josep; Llobet-Navas, David; Roma, Josep; Posas, Francesc; de Nadal, Eulàlia; Gallego, Soledad; Moreno, Lucas; Segura, Miguel F
BAF
细胞生物学
表观遗传
染色质重塑
发表日期：2022
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Metabolomic Analysis Points to Bioactive Lipid Species and Acireductone Dioxygenase 1 (ADI1) as Potential Therapeutic Targets in Poor Prognosis Endometrial Cancer

代谢组学分析表明，生物活性脂质和乙酰还原酶1 (ADI1) 可能是预后不良子宫内膜癌的潜在治疗靶点

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers14122842
Gatius, Sònia; Jove, Mariona; Megino-Luque, Cristina; Albertí-Valls, Manel; Yeramian, Andree; Bonifaci, Nuria; Piñol, Miquel; Santacana, Maria; Pradas, Irene; Llobet-Navas, David; Pamplona, Reinald; Matías-Guiu, Xavier; Eritja, Núria
肿瘤
子宫内膜癌
肿瘤免疫
代谢
发表日期：2022
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The oral KIF11 inhibitor 4SC-205 exhibits antitumor activity and potentiates standard and targeted therapies in primary and metastatic neuroblastoma models

口服KIF11抑制剂4SC-205具有抗肿瘤活性，并能增强原发性和转移性神经母细胞瘤模型中的标准疗法和靶向疗法的疗效。

期刊:Clinical and Translational Medicine
影响因子:6.8
doi:10.1002/ctm2.533
Masanas, Marc; Masiá, Nuria; Suárez-Cabrera, Leticia; Olivan, Mireia; Soriano, Aroa; Majem, Blanca; Devis-Jauregui, Laura; Burgos-Panadero, Rebeca; Jiménez, Carlos; Rodriguez-Sodupe, Pau; Boloix, Ariadna; Toledano, Ignasi; Guillén, Gabriela; Navarro, Alexandra; Llobet-Navas, David; Villanueva, Alberto; Sánchez de Toledo, Josep; Roma, Josep; Noguera, Rosa; Moreno, Lucas; Krauss, Rolf; Gallego, Soledad; Santamaria, Anna; Segura, Miguel F
KIF11
细胞生物学
肿瘤
肿瘤免疫
发表日期：2021
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Neuronal Differentiation-Related Epigenetic Regulator ZRF1 Has Independent Prognostic Value in Neuroblastoma but Is Functionally Dispensable In Vitro

神经元分化相关表观遗传调控因子ZRF1在神经母细胞瘤中具有独立的预后价值，但在体外功能上并非必需。

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers13194845
Jiménez, Carlos; Antonelli, Roberta; Masanas, Marc; Soriano, Aroa; Devis-Jauregui, Laura; Camacho, Jessica; Magdaleno, Ainara; Guillén, Gabriela; Hladun, Raquel; Jubierre, Luz; Roma, Josep; Llobet-Navas, David; Sánchez de Toledo, Josep; Moreno, Lucas; Gallego, Soledad; Segura, Miguel F
信号转导
细胞生物学
表观遗传
神经科学
发表日期：2021
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Erratum to: HDAC6 activity is a non-oncogene addiction hub for inflammatory breast cancers

更正：HDAC6活性是炎症性乳腺癌的非癌基因依赖中心

期刊:Breast Cancer Research
影响因子:5.6
doi:10.1186/s13058-017-0841-6
Putcha, Preeti; Yu, Jiyang; Rodriguez-Barrueco, Ruth; Saucedo-Cuevas, Laura; Villagrasa, Patricia; Murga-Penas, Eva; Quayle, Steven N; Yang, Min; Castro, Veronica; Llobet-Navas, David; Birnbaum, Daniel; Finetti, Pascal; Woodward, Wendy A; Bertucci, François; Alpaugh, Mary L; Califano, Andrea; Silva, Jose
肿瘤
炎症
肿瘤免疫
炎症/感染
乳腺癌
HDAC6
发表日期：2017
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