Lloyd R Stephen相关文献与解析，生知库 | 链接生命科学的每一步

Inhibition by 4-(4-Bromo-2-oxo-3H-benzimidazol-1-yl)-N-(4-iodophenyl)piperidine-1-carboxamide (TH5487) of the Activity of Human 8-Oxoguanine DNA Glycosylase-1 (OGG1) for the Excision of 2,6-Diamino-4-hydroxy-5-formamidopyrimidine, 4,6-Diamino-5-formamidopyrimidine, and 8-Oxoguanine from Oxidatively Damaged DNA

4-(4-溴-2-氧代-3H-苯并咪唑-1-基)-N-(4-碘苯基)哌啶-1-甲酰胺 (TH5487) 对人 8-氧鸟嘌呤 DNA 糖基化酶-1 (OGG1) 从氧化损伤 DNA 中切除 2,6-二氨基-4-羟基-5-甲酰胺基嘧啶、4,6-二氨基-5-甲酰胺基嘧啶和 8-氧鸟嘌呤的活性具有抑制作用

期刊:Biochemistry

影响因子:3

doi:10.1021/acs.biochem.4c00419

Jaruga, Pawel; Kant, Melis; Luzadder, Michael M; Lloyd, R Stephen; Boldogh, Istvan; Dizdaroglu, Miral

Role of NEIL1 in genome maintenance

NEIL1在基因组维持中的作用

期刊:DNA Repair

影响因子:2.7

doi:10.1016/j.dnarep.2025.103820

McCullough, Amanda K; Minko, Irina G; Luzadder, Michael M; Zuckerman, Jamie T; Vartanian, Vladimir L; Jaruga, Pawel; Dizdaroglu, Miral; Lloyd, R Stephen

发表日期：2025

文献求助收藏

Aflatoxin B(1)-Induced Hepatic Mutagenesis in Mice Expressing Gene-Edited Neil1.

黄曲霉毒素 B(1) 诱导表达基因编辑 Neil1 的小鼠发生肝脏突变

期刊:Environmental and Molecular Mutagenesis

影响因子:2.3

doi:10.1002/em.70014

Minko Irina G, Vartanian Vladimir L, Luzadder Michael M, Wang Yingming, Fedorov Lev M, McCullough Amanda K, Lloyd R Stephen

其它

发表日期：2025

文献求助收藏

In vitro evidence for bisphenol A as a human liver carcinogen: Environmentally relevant doses inhibit cancer-protective ESR1 signaling in a human liver cell line

体外实验证据表明双酚A是人类肝癌致癌物：环境相关剂量可抑制人肝细胞系中具有抗癌作用的ESR1信号通路。

期刊:

影响因子:

doi:10.64898/2025.12.18.695265

Weeks, Emma; Kennedy, Scott; Searles, Robert; Carrothers, Samantha; Davis, Brett; Carbone, Lucia; Turker, Mitchell; Lloyd, R Stephen; Weinhouse, Caren

Mass Spectrometry-Based Method to Measure Aflatoxin B(1) DNA Adducts in Formalin-Fixed Paraffin-Embedded Tissues

基于质谱法测定福尔马林固定石蜡包埋组织中黄曲霉毒素B1 DNA加合物的方法

期刊:Chemical Research in Toxicology

影响因子:3.8

doi:10.1021/acs.chemrestox.4c00005

Bellamri, Medjda; Yao, Lihua; Tomar, Rachana; Vartanian, Vladimir; Rizzo, Carmelo J; Stone, Michael P; Groopman, John D; Lloyd, R Stephen; Turesky, Robert J

发表日期：2024

文献求助收藏

Functional characterization of single nucleotide polymorphic variants of DNA repair enzyme NEIL1 in South Asian populations

南亚人群中DNA修复酶NEIL1单核苷酸多态性变异的功能特征

期刊:DNA Repair

影响因子:2.7

doi:10.1016/j.dnarep.2024.103695

Zuckerman, Jamie T; Jackson, Asia Sage; Minko, Irina G; Kant, Melis; Jaruga, Pawel; Stone, Michael P; Dizdaroglu, Miral; McCullough, Amanda K; Lloyd, R Stephen

发表日期：2024

文献求助收藏

The aflatoxin B(1)-induced imidazole ring-opened guanine adduct: High mutagenic potential that is minimally affected by sequence context

黄曲霉毒素B1诱导的咪唑开环鸟嘌呤加合物：具有高诱变潜力，且受序列环境影响极小

期刊:Environmental and Molecular Mutagenesis

影响因子:2.3

doi:10.1002/em.22556

Minko, Irina G; Kellum, Andrew H Jr; Stone, Michael P; Lloyd, R Stephen

发表日期：2024

文献求助收藏

Base excision repair of the N-(2-deoxy-d-erythro-pentofuranosyl)-urea lesion by the hNEIL1 glycosylase

hNEIL1糖基化酶对N-(2-脱氧-D-赤式-戊呋喃糖基)-脲损伤的碱基切除修复

期刊:Nucleic Acids Research

影响因子:13.1

doi:10.1093/nar/gkad164

Tomar, Rachana; Minko, Irina G; Sharma, Pankaj; Kellum, Andrew H; Lei, Li; Harp, Joel M; Iverson, T M; Lloyd, R Stephen; Egli, Martin; Stone, Michael P

发表日期：2023

文献求助收藏

The Distinct Roles of NEIL1 and XPA in Limiting Aflatoxin B1-Induced Mutagenesis in Mice.

NEIL1 和 XPA 在限制黄曲霉毒素 B1 诱导的小鼠突变中发挥着不同的作用

Aflatoxin B(1)-induced DNA adduct formation in murine kidney and liver

黄曲霉毒素B1诱导小鼠肾脏和肝脏DNA加合物的形成

4-(4-溴-2-氧代-3H-苯并咪唑-1-基)-N-(4-碘苯基)哌啶-1-甲酰胺 (TH5487) 对人 8-氧鸟嘌呤 DNA 糖基化酶-1 (OGG1) 从氧化损伤 DNA 中切除 2,6-二氨基-4-羟基-5-甲酰胺基嘧啶、4,6-二氨基-5-甲酰胺基嘧啶和 8-氧鸟嘌呤的活性具有抑制作用

Role of NEIL1 in genome maintenance

NEIL1在基因组维持中的作用

Aflatoxin B(1)-Induced Hepatic Mutagenesis in Mice Expressing Gene-Edited Neil1.

黄曲霉毒素 B(1) 诱导表达基因编辑 Neil1 的小鼠发生肝脏突变

In vitro evidence for bisphenol A as a human liver carcinogen: Environmentally relevant doses inhibit cancer-protective ESR1 signaling in a human liver cell line

体外实验证据表明双酚A是人类肝癌致癌物：环境相关剂量可抑制人肝细胞系中具有抗癌作用的ESR1信号通路。

Mass Spectrometry-Based Method to Measure Aflatoxin B(1) DNA Adducts in Formalin-Fixed Paraffin-Embedded Tissues

基于质谱法测定福尔马林固定石蜡包埋组织中黄曲霉毒素B1 DNA加合物的方法

Functional characterization of single nucleotide polymorphic variants of DNA repair enzyme NEIL1 in South Asian populations

南亚人群中DNA修复酶NEIL1单核苷酸多态性变异的功能特征

The aflatoxin B(1)-induced imidazole ring-opened guanine adduct: High mutagenic potential that is minimally affected by sequence context

黄曲霉毒素B1诱导的咪唑开环鸟嘌呤加合物：具有高诱变潜力，且受序列环境影响极小

Base excision repair of the N-(2-deoxy-d-erythro-pentofuranosyl)-urea lesion by the hNEIL1 glycosylase

hNEIL1糖基化酶对N-(2-脱氧-D-赤式-戊呋喃糖基)-脲损伤的碱基切除修复