日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Predicting epistasis across proteins by structural logic

利用结构逻辑预测蛋白质间的上位性

Tang, Michelle; Cromie, Gareth A; Kabir, Anowarul; Timour, Martin S; Ashmead, Julee; Lo, Russell S; Corley, Nathaniel; DiMaio, Frank; Morizono, Hiroki; Caldovic, Ljubica; Ah Mew, Nicholas; Gropman, Andrea; Shehu, Amarda; Dudley, Aimée M

Two commonly reported incidental variants in OTC are associated with late-onset disease

OTC基因中两种常见的偶然变异与晚发性疾病相关。

Lang, Steven H; Lo, Russell S; Cromie, Gareth A; Dudley, Aimée M; Mew, Nicholas Ah; Simpson, Kara; Sutton, Vernon Reid; Darilek, Sandra; Ali, Saima; Snyder, Matthew T; Lee, Brendan; Marom, Ronit; Nagamani, Sandesh C S; Burrage, Lindsay C

CYClones: A highly powered, fully genotyped, 8-parent yeast mapping population

CYClones:一个高效率、完全基因分型的8亲本酵母作图群体

Cromie, Gareth A; Lo, Russell S; Morgan, Trey S; Clark, Anne E; Ashmead, Julee; Timour, Martin S; Sirr, Amy; Akey, Joshua M; Dudley, Aimée M

Pervasive context-dependent effects in the genetic architecture of complex and quantitative traits revealed by a powerful multiparent mapping population in yeast

利用强大的多亲本作图群体在酵母中揭示了复杂性状和数量性状的遗传结构中普遍存在的上下文依赖性效应

Cromie, Gareth A; Lo, Russell S; Ames, Lauren; Morgan, Trey S; Owens, Katherine; Clark, Anne E; Timour, Martin S; Ashmead, Julee; Tang, Michelle; Kutz, J Nathan; Akey, Joshua M; Dudley, Aimée M

The functional impact of 1,570 individual amino acid substitutions in human OTC

1570个氨基酸替换对人类OTC的功能影响

Lo, Russell S; Cromie, Gareth A; Tang, Michelle; Teng, Kevin; Owens, Katherine; Sirr, Amy; Kutz, J Nathan; Morizono, Hiroki; Caldovic, Ljubica; Ah Mew, Nicholas; Gropman, Andrea; Dudley, Aimée M

A yeast-based complementation assay elucidates the functional impact of 200 missense variants in human PSAT1

基于酵母的互补试验阐明了人类PSAT1中200个错义变异的功能影响

Sirr, Amy; Lo, Russell S; Cromie, Gareth A; Scott, Adrian C; Ashmead, Julee; Heyesus, Mirutse; Dudley, Aimée M

Exploiting the Autozygome to Support Previously Published Mendelian Gene-Disease Associations: An Update

利用纯合子支持先前发表的孟德尔基因-疾病关联:最新进展

Maddirevula, Sateesh; Shamseldin, Hanan E; Sirr, Amy; AlAbdi, Lama; Lo, Russell S; Ewida, Nour; Al-Qahtani, Mashael; Hashem, Mais; Abdulwahab, Firdous; Aboyousef, Omar; Kaya, Namik; Monies, Dorota; Salem, May H; Al Harbi, Naffaa; Aldhalaan, Hesham M; Alzaidan, Hamad; Almanea, Hadeel M; Alsalamah, Abrar K; Al Mutairi, Fuad; Ismail, Samira; Abdel-Salam, Ghada M H; Alhashem, Amal; Asery, Ali; Faqeih, Eissa; AlQassmi, Amal; Al-Hamoudi, Waleed; Algoufi, Talal; Shagrani, Mohammad; Dudley, Aimée M; Alkuraya, Fowzan S

Massively parallel single-amino-acid mutagenesis

大规模平行单氨基酸诱变

Kitzman, Jacob O; Starita, Lea M; Lo, Russell S; Fields, Stanley; Shendure, Jay

A tetO Toolkit To Alter Expression of Genes in Saccharomyces cerevisiae

用于改变酿酒酵母基因表达的 tetO 工具包

Cuperus, Josh T; Lo, Russell S; Shumaker, Lucia; Proctor, Julia; Fields, Stanley

Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis.

通过高通量诱变鉴定的 E3 泛素连接酶活性增强突变

Starita Lea M, Pruneda Jonathan N, Lo Russell S, Fowler Douglas M, Kim Helen J, Hiatt Joseph B, Shendure Jay, Brzovic Peter S, Fields Stanley, Klevit Rachel E