In vivo targeting of ADAM9 gene expression using lentivirus-delivered shRNA suppresses prostate cancer growth by regulating REG4 dependent cell cycle progression.
利用慢病毒载体递送的 shRNA 在体内靶向 ADAM9 基因表达,通过调节 REG4 依赖的细胞周期进程来抑制前列腺癌的生长
期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0053795
Liu Che-Ming, Hsieh Chia-Ling, He Yun-Chi, Lo Sen-Jei, Liang Ji-An, Hsieh Teng-Fu, Josson Sajni, Chung Leland W K, Hung Mien-Chie, Sung Shian-Ying