日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Relationship Between Dietary and Supplemental omega-3 Highly Unsaturated Fatty Acid Intake, Blood and Tissue omega-3 Highly Unsaturated Fatty Acid Concentrations, and Colorectal Polyp Recurrence: A Secondary Analysis of the seAFOod Polyp Prevention Trial

膳食和补充剂中ω-3高度不饱和脂肪酸的摄入量、血液和组织中ω-3高度不饱和脂肪酸的浓度与结直肠息肉复发的关系:seAFOod息肉预防试验的二次分析

Sun, Ge; Fuller, Harriett; Fenton, Hayley; Race, Amanda D; Downing, Amy; Rees, Colin J; Brown, Louise C; Loadman, Paul M; Williams, Elizabeth A; Hull, Mark A

The effect of aspirin and eicosapentaenoic acid on urinary biomarkers of prostaglandin E(2) synthesis and platelet activation in participants of the seAFOod polyp prevention trial

阿司匹林和二十碳五烯酸对 seAFOod 息肉预防试验参与者尿液中前列腺素 E(2) 合成和血小板活化生物标志物的影响

Sun, Ge; Fuller, Harriett; Fenton, Hayley; Race, Amanda D; Downing, Amy; Williams, Elizabeth A; Rees, Colin J; Brown, Louise C; Loadman, Paul M; Hull, Mark A

Hypoxia-Responsive Prodrug of ATR Inhibitor, AZD6738, Selectively Eradicates Treatment-Resistant Cancer Cells

ATR 抑制剂 AZD6738 的缺氧反应性前药可选择性地消灭耐药癌细胞

Francis M Barnieh, Goreti Ribeiro Morais, Paul M Loadman, Robert A Falconer, Sherif F El-Khamisy

Cancer-specific glycosylation of CD13 impacts its detection and activity in preclinical cancer tissues

CD13 的癌症特异性糖基化影响其在临床前癌症组织中的检测和活性

Francis M Barnieh, Sebastian P Galuska, Paul M Loadman, Simon Ward, Robert A Falconer, Sherif F El-Khamisy

Polymorphisms in Cyclooxygenase, Lipoxygenase, and TP53 Genes Predict Colorectal Polyp Risk Reduction by Aspirin in the seAFOod Polyp Prevention Trial

环氧合酶、脂氧合酶和TP53基因的多态性可预测阿司匹林在seAFOod息肉预防试验中降低结直肠息肉风险的效果

Davies, John R; Mell, Tracey; Fuller, Harriett; Harland, Mark; Saleh, Rasha N M; Race, Amanda D; Rees, Colin J; Brown, Louise C; Loadman, Paul M; Downing, Amy; Minihane, Anne Marie; Williams, Elizabeth A; Hull, Mark A

Randomised, placebo-controlled, phase 3 trial of the effect of the omega-3 polyunsaturated fatty acid eicosapentaenoic acid (EPA) on colorectal cancer recurrence and survival after surgery for resectable liver metastases: EPA for Metastasis Trial 2 (EMT2) study protocol

一项随机、安慰剂对照的3期临床试验,旨在研究ω-3多不饱和脂肪酸二十碳五烯酸(EPA)对结直肠癌复发及可切除肝转移瘤术后生存率的影响:EPA转移瘤治疗试验2(EMT2)研究方案

Hull, Mark A; Ow, Pei Loo; Ruddock, Sharon; Brend, Tim; Smith, Alexandra F; Marshall, Helen; Song, Mingyang; Chan, Andrew T; Garrett, Wendy S; Yilmaz, Omer; Drew, David A; Collinson, Fiona; Cockbain, Andrew J; Jones, Robert; Loadman, Paul M; Hall, Peter S; Moriarty, Catherine; Cairns, David A; Toogood, Giles J

A Single Short 'Tone Burst' Results in Optimal Drug Delivery to Tumours Using Ultrasound-Triggered Therapeutic Microbubbles

利用超声触发的治疗性微泡,单次短促的“脉冲串”可实现向肿瘤的最佳药物递送

Ingram, Nicola; McVeigh, Laura E; Abou-Saleh, Radwa H; Batchelor, Damien V B; Loadman, Paul M; McLaughlan, James R; Markham, Alexander F; Evans, Stephen D; Coletta, P Louise

Cytochrome P450 Binding and Bioactivation of Tumor-Targeted Duocarmycin Agents

肿瘤靶向多卡米星药物的细胞色素 P450 结合和生物活化

Aaron G Bart, Goreti Morais, Venu R Vangala, Paul M Loadman, Klaus Pors, Emily E Scott

Implementing subtype-specific pre-clinical models of breast cancer to study pre-treatment aspirin effects

实施乳腺癌亚型特异性临床前模型来研究治疗前阿司匹林的效果

Ian S Miller, Sonja Khan, Liam P Shiels, Sudipto Das, Alice C O' Farrell, Kate Connor, Adam Lafferty, Bruce Moran, Claudio Isella, Paul Loadman, Emer Conroy, Susan Cohrs, Roger Schibli, Robert S Kerbel, William M Gallagher, Elisabetta Marangoni, Kathleen Bennett, Darran P O' Connor, Róisín M Dwyer, 

Luminal Bioavailability of Orally Administered ω-3 PUFAs in the Distal Small Intestine, and Associated Changes to the Ileal Microbiome, in Humans with a Temporary Ileostomy

口服ω-3多不饱和脂肪酸在远端小肠腔内的生物利用度及其对暂时性回肠造口患者回肠微生物群的影响

Nana, Gael; Mitra, Suparna; Watson, Henry; Young, Caroline; Wood, Henry M; Perry, Sarah L; Race, Amanda D; Quirke, Philip; Toogood, Giles J; Loadman, Paul M; Hull, Mark A