日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Activation of TSLP-IL-9 Axis Hinders the Antifibrotic Effect of ST2 Deficiency in Pulmonary Fibrosis

TSLP-IL-9轴的激活会阻碍ST2缺陷在肺纤维化中的抗纤维化作用

Atamas, Sergei P; Lockatell, Virginia; Mei, Zhongcheng; Tulapurkar, Mohan E; Lugkey, Katerina N; Krupnick, Alexander Sasha; Luzina, Irina G

Therapeutic targeting of full-length interleukin-33 protein levels with cell-permeable decoy peptides attenuates fibrosis in the bleomycin model in vivo

利用细胞可渗透的诱饵肽靶向全长白细胞介素-33蛋白水平,可减轻博来霉素模型体内的纤维化。

Atamas, Sergei P; Lockatell, Virginia; Todd, Nevins W; Papadimitriou, John C; Rus, Violeta; Lugkey, Katerina N; Vogel, Stefanie N; Toshchakov, Vladimir Y; Luzina, Irina G

The IL-33/ST2 Axis Is Not Required for the Profibrotic Effect of IL-33 in the Lungs

IL-33/ST2轴并非IL-33在肺部发挥促纤维化作用所必需

Atamas, Sergei P; Lockatell, Virginia; Todd, Nevins W; Luzina, Irina G

Full-length IL-33 augments pulmonary fibrosis in an ST2- and Th2-independent, non-transcriptomic fashion

全长IL-33以一种不依赖于ST2和Th2细胞、非转录组的方式加剧肺纤维化。

Luzina, Irina G; Lockatell, Virginia; Courneya, Jean-Paul; Mei, Zhongcheng; Fishelevich, Rita; Kopach, Pavel; Pickering, Edward M; Kang, Phillip H; Krupnick, Alexander S; Todd, Nevins W; Vogel, Stefanie N; Atamas, Sergei P

Regulator of Cell Cycle Protein (RGCC/RGC-32) Protects against Pulmonary Fibrosis

细胞周期调节蛋白(RGCC/RGC-32)可预防肺纤维化

Luzina, Irina G; Rus, Violeta; Lockatell, Virginia; Courneya, Jean-Paul; Hampton, Brian S; Fishelevich, Rita; Misharin, Alexander V; Todd, Nevins W; Badea, Tudor C; Rus, Horea; Atamas, Sergei P

Therapeutic Effect of Neuraminidase-1-Selective Inhibition in Mouse Models of Bleomycin-Induced Pulmonary Inflammation and Fibrosis

神经氨酸酶-1选择性抑制对博来霉素诱发的肺部炎症和纤维化小鼠模型的治疗作用

Irina G Luzina, Erik P Lillehoj, Virginia Lockatell, Sang W Hyun, Katerina N Lugkey, Akihiro Imamura, Hideharu Ishida, Christopher W Cairo, Sergei P Atamas, Simeon E Goldblum

Full-length IL-33 regulates Smad3 phosphorylation and gene transcription in a distinctive AP2-dependent manner

全长 IL-33 以独特的 AP2 依赖方式调节 Smad3 磷酸化和基因转录

Irina G Luzina, Rita Fishelevich, Brian S Hampton, Jean-Paul Courneya, Francesca R Parisella, Katerina N Lugkey, Frank X Baleno, Dohyun Choi, Pavel Kopach, Virginia Lockatell, Nevins W Todd, Sergei P Atamas

The full-length interleukin-33 (FLIL33)-importin-5 interaction does not regulate nuclear localization of FLIL33 but controls its intracellular degradation

全长白细胞介素-33 (FLIL33)-importin-5 相互作用不调节 FLIL33 的核定位,但控制其细胞内降解

Andrew Clerman, Zahid Noor, Rita Fishelevich, Virginia Lockatell, Brian S Hampton, Nirav G Shah, Mariah V Salcedo, Nevins W Todd, Sergei P Atamas, Irina G Luzina

Elevated expression of NEU1 sialidase in idiopathic pulmonary fibrosis provokes pulmonary collagen deposition, lymphocytosis, and fibrosis

特发性肺纤维化中 NEU1 唾液酸酶表达升高会引起肺胶原沉积、淋巴细胞增多和纤维化

Irina G Luzina, Virginia Lockatell, Sang W Hyun, Pavel Kopach, Phillip H Kang, Zahid Noor, Anguo Liu, Erik P Lillehoj, Chunsik Lee, Alba Miranda-Ribera, Nevins W Todd, Simeon E Goldblum, Sergei P Atamas

Pharmacological In Vivo Inhibition of S-Nitrosoglutathione Reductase Attenuates Bleomycin-Induced Inflammation and Fibrosis

体内药理学抑制 S-亚硝基谷胱甘肽还原酶可减轻博来霉素诱导的炎症和纤维化

Irina G Luzina, Virginia Lockatell, Nevins W Todd, Pavel Kopach, Helen S Pentikis, Sergei P Atamas