Lockett Stephen J相关文献与解析，生知库

Liu, Fang; He, Rui; Sheeley, Thomas; Scheiblin, David A; Lockett, Stephen J; Ridnour, Lisa A; Wink, David A; Jensen, Mark; Cortner, Janelle; Zaki, George

细胞生物学

单细胞

发表日期：2026

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TRAIL induces cytokine production via the NFkB2 pathway promoting neutrophil chemotaxis and neutrophil-mediated immune-suppression in triple negative breast cancer cells

TRAIL通过NF-κB2通路诱导细胞因子产生，促进中性粒细胞趋化和中性粒细胞介导的免疫抑制，从而增强三阴性乳腺癌细胞的免疫活性。

期刊:Cancer Letters

影响因子:10.1

doi:10.1016/j.canlet.2025.217692

Kundu, Manjari; Greer, Yoshimi E; Lobanov, Alexei; Ridnour, Lisa; Donahue, Renee N; Ng, Yeap; Ratnayake, Shashi; White, Karley; Voeller, Donna; Weltz, Sarah; Chen, Qingrong; Lockett, Stephen J; Cam, Maggie; Meerzaman, Daoud; Wink, David A; Weigert, Roberto; Lipkowitz, Stanley

Elevated tumor NOS2/COX2 promotes immunosuppressive phenotypes associated with poor survival in ER- breast cancer

肿瘤NOS2/COX2水平升高会促进与ER阴性乳腺癌患者预后不良相关的免疫抑制表型。

期刊:JCI Insight

影响因子:6.1

doi:10.1172/jci.insight.193091

Ridnour, Lisa A; Cheng, Robert Ys; Heinz, William F; Pore, Milind; Gonzalez, Ana L; Femino, Elise L; Moffat, Rebecca L; Wink, Adelaide L; Imtiaz, Fatima; Coutinho, Leandro L; Butcher, Donna; Edmondson, Elijah F; Rangel, M Cristina; Wong, Stephen Tc; Lipkowitz, Stanley; Glynn, Sharon A; Vitek, Michael P; McVicar, Daniel W; Li, Xiaoxian; Anderson, Stephen K; Paolocci, Nazareno; Hewitt, Stephen M; Ambs, Stefan; Billiar, Timothy R; Chang, Jenny C; Lockett, Stephen J; Wink, David A

SPAC: a scalable, integrated enterprise platform for end-to-end single cell spatial analysis of multiplexed tissue imaging

SPAC：一个可扩展的集成企业平台，用于对多重组织成像进行端到端的单细胞空间分析

期刊:

影响因子:

doi:10.1101/2025.04.02.646782

Liu, Fang; He, Rui; Sheeley, Thomas; Scheiblin, David; Lockett, Stephen J; Ridnour, Lisa A; Wink, David A; Jensen, Mark; Cortner, Janelle; Zaki, George

NOS2 and COX-2 Co-Expression Promotes Cancer Progression: A Potential Target for Developing Agents to Prevent or Treat Highly Aggressive Breast Cancer

NOS2 和 COX-2 共表达促进癌症进展：开发预防或治疗高侵袭性乳腺癌药物的潜在靶点

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms25116103

Coutinho, Leandro L; Femino, Elise L; Gonzalez, Ana L; Moffat, Rebecca L; Heinz, William F; Cheng, Robert Y S; Lockett, Stephen J; Rangel, M Cristina; Ridnour, Lisa A; Wink, David A

TRAIL-induced cytokine production via NFKB2 pathway promotes neutrophil chemotaxis and immune suppression in triple negative breast cancers

TRAIL通过NFKB2通路诱导细胞因子产生，促进三阴性乳腺癌中性粒细胞趋化和免疫抑制。

期刊:

影响因子:

doi:10.1101/2024.07.19.604341

Kundu, Manjari; Greer, Yoshimi E; Lobanov, Alexei; Ridnour, Lisa; Donahue, Renee N; Ng, Yeap; Ratnayake, Shashi; Voeller, Donna; Weltz, Sarah; Chen, Qingrong; Lockett, Stephen J; Cam, Maggie; Meerzaman, Daoud; Wink, David A; Weigert, Roberto; Lipkowitz, Stanley

Interferon-gamma is Quintessential for NOS2 and COX2 Expression in ER (-) Breast Tumors that Lead to Poor Outcome

干扰素-γ对于ER(-)乳腺肿瘤中NOS2和COX2的表达至关重要，而这些肿瘤会导致不良预后。

期刊:

影响因子:

doi:10.1101/2023.04.06.535916

Cheng, Robert Ys; Ridnour, Lisa A; Wink, Adelaide L; Gonzalez, Ana L; Femino, Elise L; Rittscher, Helene; Somasundarum, Veena; Heinz, William F; Coutinho, Leandro; Cristina Rangel, M; Edmondson, Elijah F; Butcher, Donna; Kinders, Robert J; Li, Xiaoxian; Wong, Stephen T C; McVicar, Daniel W; Anderson, Steven K; Pore, Milind; Hewitt, Stephen M; Billiar, Timothy R; Glynn, Sharon; Chang, Jenny C; Lockett, Stephen J; Ambs, Stefan; Wink, David A

Nitric Oxide Modulates Metabolic Processes in the Tumor Immune Microenvironment

一氧化氮调节肿瘤免疫微环境中的代谢过程

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms22137068

McGinity, Christopher L; Palmieri, Erika M; Somasundaram, Veena; Bhattacharyya, Dibyangana D; Ridnour, Lisa A; Cheng, Robert Y S; Ryan, Aideen E; Glynn, Sharon A; Thomas, Douglas D; Miranda, Katrina M; Anderson, Stephen K; Lockett, Stephen J; McVicar, Daniel W; Wink, David A

Inducible nitric oxide synthase-derived extracellular nitric oxide flux regulates proinflammatory responses at the single cell level

诱导型一氧化氮合酶衍生的细胞外一氧化氮通量在单细胞水平上调节促炎反应

期刊:Redox Biology

影响因子:11.9

doi:10.1016/j.redox.2019.101354

Somasundaram, Veena; Gilmore, Anne C; Basudhar, Debashree; Palmieri, Erika Mariana; Scheiblin, David A; Heinz, William F; Cheng, Robert Y S; Ridnour, Lisa A; Altan-Bonnet, Grégoire; Lockett, Stephen J; McVicar, Daniel W; Wink, David A

Collective cancer cell invasion requires RNA accumulation at the invasive front

癌细胞的集体侵袭需要侵袭前沿的RNA积累。

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2010872117

Chrisafis, George; Wang, Tianhong; Moissoglu, Konstadinos; Gasparski, Alexander N; Ng, Yeap; Weigert, Roberto; Lockett, Stephen J; Mili, Stavroula

SPAC: a scalable and integrated enterprise platform for single-cell spatial analysis

SPAC：一个可扩展且集成的单细胞空间分析企业平台

TRAIL induces cytokine production via the NFkB2 pathway promoting neutrophil chemotaxis and neutrophil-mediated immune-suppression in triple negative breast cancer cells

TRAIL通过NF-κB2通路诱导细胞因子产生，促进中性粒细胞趋化和中性粒细胞介导的免疫抑制，从而增强三阴性乳腺癌细胞的免疫活性。

Elevated tumor NOS2/COX2 promotes immunosuppressive phenotypes associated with poor survival in ER- breast cancer

肿瘤NOS2/COX2水平升高会促进与ER阴性乳腺癌患者预后不良相关的免疫抑制表型。

SPAC: a scalable, integrated enterprise platform for end-to-end single cell spatial analysis of multiplexed tissue imaging

SPAC：一个可扩展的集成企业平台，用于对多重组织成像进行端到端的单细胞空间分析

NOS2 and COX-2 Co-Expression Promotes Cancer Progression: A Potential Target for Developing Agents to Prevent or Treat Highly Aggressive Breast Cancer

NOS2 和 COX-2 共表达促进癌症进展：开发预防或治疗高侵袭性乳腺癌药物的潜在靶点

TRAIL-induced cytokine production via NFKB2 pathway promotes neutrophil chemotaxis and immune suppression in triple negative breast cancers

TRAIL通过NFKB2通路诱导细胞因子产生，促进三阴性乳腺癌中性粒细胞趋化和免疫抑制。

Interferon-gamma is Quintessential for NOS2 and COX2 Expression in ER (-) Breast Tumors that Lead to Poor Outcome

干扰素-γ对于ER(-)乳腺肿瘤中NOS2和COX2的表达至关重要，而这些肿瘤会导致不良预后。

Nitric Oxide Modulates Metabolic Processes in the Tumor Immune Microenvironment

一氧化氮调节肿瘤免疫微环境中的代谢过程

Inducible nitric oxide synthase-derived extracellular nitric oxide flux regulates proinflammatory responses at the single cell level

诱导型一氧化氮合酶衍生的细胞外一氧化氮通量在单细胞水平上调节促炎反应

Collective cancer cell invasion requires RNA accumulation at the invasive front

癌细胞的集体侵袭需要侵袭前沿的RNA积累。