日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Novel Pure αVβ3 Integrin Antagonists That Do Not Induce Receptor Extension, Prime the Receptor, or Enhance Angiogenesis at Low Concentrations.

新型纯αVβ3整合素拮抗剂，低浓度下不诱导受体延伸、启动受体或增强血管生成

期刊:ACS Pharmacology and Translational Science
影响因子:3.7
doi:10.1021/acsptsci.9b00041
Li Jihong, Fukase Yoshiyuki, Shang Yi, Zou Wei, Muñoz-Félix José M, Buitrago Lorena, van Agthoven Johannes, Zhang Yixiao, Hara Ryoma, Tanaka Yuta, Okamoto Rei, Yasui Takeshi, Nakahata Takashi, Imaeda Toshihiro, Aso Kazuyoshi, Zhou Yuchen, Locuson Charles, Nesic Dragana, Duggan Mark, Takagi Junichi, Vaughan Roger D, Walz Thomas, Hodivala-Dilke Kairbaan, Teitelbaum Steven L, Arnaout M Amin, Filizola Marta, Foley Michael A, Coller Barry S
心血管
血管生成
发表日期：2019
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Discovery and Optimization of Potent and CNS Penetrant M(5)-Preferring Positive Allosteric Modulators Derived from a Novel, Chiral N-(Indanyl)piperidine Amide Scaffold

发现和优化源自新型手性N-(茚满基)哌啶酰胺骨架的高效且具有中枢神经系统穿透性的M(5)优先正向变构调节剂

期刊:ACS Chemical Neuroscience
影响因子:3.9
doi:10.1021/acschemneuro.8b00126
Bender, Aaron M; Cho, Hyekyung P; Nance, Kellie D; Lingenfelter, Kaelyn S; Luscombe, Vincent B; Gentry, Patrick R; Voigtritter, Karl; Berizzi, Alice E; Sexton, Patrick M; Langmead, Christopher J; Christopoulos, Arthur; Locuson, Charles W; Bridges, Thomas M; Chang, Sichen; O'Neill, Jordan C; Zhan, Xiaoyan; Niswender, Colleen M; Jones, Carrie K; Conn, P Jeffrey; Lindsley, Craig W
神经科学
发表日期：2018
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Subcutaneous meloxicam suspension pharmacokinetics in mice and dose considerations for postoperative analgesia

小鼠皮下注射美洛昔康混悬液的药代动力学及术后镇痛的剂量考虑

期刊:Journal of Veterinary Pharmacology and Therapeutics
影响因子:1.7
doi:10.1111/jvp.12297
Chen, Patty H; Boyd, Kelli L; Fickle, Erin K; Locuson, Charles W
发表日期：2016
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Synthesis and structure-activity relationships of a series of 4-methoxy-3-(piperidin-4-yl)oxy benzamides as novel inhibitors of the presynaptic choline transporter

合成一系列4-甲氧基-3-(哌啶-4-基)氧基苯甲酰胺类化合物及其作为突触前胆碱转运蛋白新型抑制剂的构效关系

期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2015.02.058
Bollinger, Sean R; Engers, Darren W; Ennis, Elizabeth A; Wright, Jane; Locuson, Charles W; Lindsley, Craig W; Blakely, Randy D; Hopkins, Corey R
神经科学
发表日期：2015
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Discovery of a highly selective PLD2 inhibitor (ML395): a new probe with improved physiochemical properties and broad-spectrum antiviral activity against influenza strains

发现一种高选择性PLD2抑制剂（ML395）：一种具有改进的理化性质和广谱抗流感病毒活性的新型探针

期刊:ChemMedChem
影响因子:3.4
doi:10.1002/cmdc.201402333
O'Reilly, Matthew C; Oguin, Thomas H 3rd; Scott, Sarah A; Thomas, Paul G; Locuson, Charles W; Morrison, Ryan D; Daniels, J Scott; Brown, H Alex; Lindsley, Craig W
微生物学
流感
发表日期：2014
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Substituted indoles as selective protease activated receptor 4 (PAR-4) antagonists: Discovery and SAR of ML354

取代吲哚类化合物作为选择性蛋白酶激活受体4 (PAR-4) 拮抗剂：ML354 的发现和构效关系研究

期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2014.08.021
Wen, Wandong; Young, Summer E; Duvernay, Matthew T; Schulte, Michael L; Nance, Kellie D; Melancon, Bruce J; Engers, Julie; Locuson, Charles W 2nd; Wood, Michael R; Daniels, J Scott; Wu, Wenjun; Lindsley, Craig W; Hamm, Heidi E; Stauffer, Shaun R
信号转导
发表日期：2014
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Preparation, characterization, and substrate metabolism of gold-immobilized cytochrome P450 2C9

金固定化细胞色素P450 2C9的制备、表征和底物代谢

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/ja0608693
Gannett, Peter M; Kabulski, Jarod; Perez, Felio A; Liu, Zhongyuan; Lederman, David; Locuson, Charles W; Ayscue, Robyn R; Thomsen, Nissa M; Tracy, Timothy S
细胞生物学
代谢
发表日期：2006
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