日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Synthetic Lethal Targeting of CDK12-Deficient Prostate Cancer with PARP Inhibitors.

利用 PARP 抑制剂对 CDK12 缺陷型前列腺癌进行合成致死靶向治疗

Chou Jonathan, Robinson Troy M, Egusa Emily A, Lodha Roshan, Zhang Meng, Badura Michelle, Mikayelyan Mane, Delavan Henry M, Swinderman Jason, Wilson Chris, Zhu Jun, Das Rajdeep, Nguyen Minh, Loehr Andrea, Golsorkhi Tony, Simmons Andrew, Abida Wassim, Chinnaiyan Arul M, Arkin Michelle R, Small Eric J, Quigley David A, Yang Lixing, Kim Minkyu, Ashworth Alan, Feng Felix Y

Rucaparib or Physician's Choice in Metastatic Prostate Cancer

转移性前列腺癌的治疗方案:Rucaparib 或医生选择

Fizazi, Karim; Piulats, Josep M; Reaume, M Neil; Ostler, Peter; McDermott, Ray; Gingerich, Joel R; Pintus, Elias; Sridhar, Srikala S; Bambury, Richard M; Emmenegger, Urban; Lindberg, Henriette; Morris, David; Nolè, Franco; Staffurth, John; Redfern, Charles; Sáez, María I; Abida, Wassim; Daugaard, Gedske; Heidenreich, Axel; Krieger, Laurence; Sautois, Brieuc; Loehr, Andrea; Despain, Darrin; Heyes, Catherine A; Watkins, Simon P; Chowdhury, Simon; Ryan, Charles J; Bryce, Alan H

Emergence of BRCA Reversion Mutations in Patients with Metastatic Castration-resistant Prostate Cancer After Treatment with Rucaparib

接受 Rucaparib 治疗后,转移性去势抵抗性前列腺癌患者出现 BRCA 基因回复突变

Loehr, Andrea; Hussain, Arif; Patnaik, Akash; Bryce, Alan H; Castellano, Daniel; Font, Albert; Shapiro, Jeremy; Zhang, Jingsong; Sautois, Brieuc; Vogelzang, Nicholas J; Chatta, Gurkamal; Courtney, Kevin; Harzstark, Andrea; Ricci, Francesco; Despain, Darrin; Watkins, Simon; King, Charmin; Nguyen, Minh; Simmons, Andrew D; Chowdhury, Simon; Abida, Wassim

Rucaparib for the Treatment of Metastatic Castration-resistant Prostate Cancer Associated with a DNA Damage Repair Gene Alteration: Final Results from the Phase 2 TRITON2 Study

Rucaparib 用于治疗与 DNA 损伤修复基因改变相关的转移性去势抵抗性前列腺癌:TRITON2 II 期研究的最终结果

Abida, Wassim; Campbell, David; Patnaik, Akash; Bryce, Alan H; Shapiro, Jeremy; Bambury, Richard M; Zhang, Jingsong; Burke, John M; Castellano, Daniel; Font, Albert; Ganju, Vinod; Hardy-Bessard, Anne-Claire; McDermott, Ray; Sautois, Brieuc; Spaeth, Dominique; Voog, Eric; Piulats, Josep M; Pintus, Elias; Ryan, Charles J; Merseburger, Axel S; Daugaard, Gedske; Heidenreich, Axel; Fizazi, Karim; Loehr, Andrea; Despain, Darrin; Simmons, Andrew D; Dowson, Melanie; Go, Jowell; Watkins, Simon P; Chowdhury, Simon

Nivolumab plus rucaparib for metastatic castration-resistant prostate cancer: results from the phase 2 CheckMate 9KD trial

纳武利尤单抗联合卢卡帕尼治疗转移性去势抵抗性前列腺癌:来自 CheckMate 9KD II 期试验的结果

Fizazi, Karim; Retz, Margitta; Petrylak, Daniel P; Goh, Jeffrey C; Perez-Gracia, Jose; Lacombe, Louis; Zschäbitz, Stefanie; Burotto, Mauricio; Mahammedi, Hakim; Gravis, Gwenaelle; Bastos, Diogo Assed; McCune, Steven L; Vázquez Limón, Juan Carlos; Kwan, Edmond M; Castellano, Daniel; Fléchon, Aude; Saad, Fred; Grimm, Marc-Oliver; Shaffer, David R; Armstrong, Andrew J; Bhagavatheeswaran, Prabhu; Amin, Neha P; Ünsal-Kaçmaz, Keziban; Wang, Xuya; Li, Jun; Loehr, Andrea; Pachynski, Russell K

A Case Study of Clinical Response to Rucaparib in a Patient with Metastatic Castration-Resistant Prostate Cancer and a RAD51B Alteration

一例伴有RAD51B基因改变的转移性去势抵抗性前列腺癌患者接受Rucaparib治疗的临床反应病例研究

Sautois, Brieuc; Loehr, Andrea; Watkins, Simon P; Schroeder, Hélène; Abida, Wassim

What Plasma Can Tell Us When Tissue Cannot: A Case Report of Genomic Testing in mCRPC and Clinical Response to Treatment With the PARP Inhibitor Rucaparib

组织无法提供的信息:血浆能告诉我们什么?mCRPC 基因组检测及 PARP 抑制剂 Rucaparib 治疗临床反应病例报告

Petrylak, Daniel P; Watkins, Simon P; Loehr, Andrea

Response to Rucaparib in BRCA-Mutant Metastatic Castration-Resistant Prostate Cancer Identified by Genomic Testing in the TRITON2 Study

TRITON2 研究中通过基因组检测鉴定的 BRCA 突变转移性去势抵抗性前列腺癌对 Rucaparib 的反应

Loehr, Andrea; Patnaik, Akash; Campbell, David; Shapiro, Jeremy; Bryce, Alan H; McDermott, Ray; Sautois, Brieuc; Vogelzang, Nicholas J; Bambury, Richard M; Voog, Eric; Zhang, Jingsong; Piulats, Josep M; Hussain, Arif; Ryan, Charles J; Merseburger, Axel S; Daugaard, Gedske; Heidenreich, Axel; Fizazi, Karim; Higano, Celestia S; Krieger, Laurence E; Sternberg, Cora N; Watkins, Simon P; Despain, Darrin; Simmons, Andrew D; Dowson, Melanie; Golsorkhi, Tony; Chowdhury, Simon; Abida, Wassim

Genomic Analysis of Circulating Tumor DNA in 3,334 Patients with Advanced Prostate Cancer Identifies Targetable BRCA Alterations and AR Resistance Mechanisms

对3334例晚期前列腺癌患者循环肿瘤DNA的基因组分析发现了可靶向的BRCA改变和AR耐药机制

Tukachinsky, Hanna; Madison, Russell W; Chung, Jon H; Gjoerup, Ole V; Severson, Eric A; Dennis, Lucas; Fendler, Bernard J; Morley, Samantha; Zhong, Lei; Graf, Ryon P; Ross, Jeffrey S; Alexander, Brian M; Abida, Wassim; Chowdhury, Simon; Ryan, Charles J; Fizazi, Karim; Golsorkhi, Tony; Watkins, Simon P; Simmons, Andrew; Loehr, Andrea; Venstrom, Jeffrey M; Oxnard, Geoffrey R

Rucaparib in Men With Metastatic Castration-Resistant Prostate Cancer Harboring a BRCA1 or BRCA2 Gene Alteration

Rucaparib 用于携带 BRCA1 或 BRCA2 基因改变的转移性去势抵抗性前列腺癌男性患者

Abida, Wassim; Patnaik, Akash; Campbell, David; Shapiro, Jeremy; Bryce, Alan H; McDermott, Ray; Sautois, Brieuc; Vogelzang, Nicholas J; Bambury, Richard M; Voog, Eric; Zhang, Jingsong; Piulats, Josep M; Ryan, Charles J; Merseburger, Axel S; Daugaard, Gedske; Heidenreich, Axel; Fizazi, Karim; Higano, Celestia S; Krieger, Laurence E; Sternberg, Cora N; Watkins, Simon P; Despain, Darrin; Simmons, Andrew D; Loehr, Andrea; Dowson, Melanie; Golsorkhi, Tony; Chowdhury, Simon