日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structure and function of the yeast amino acid-sensing SEAC-EGOC supercomplex

酵母氨基酸感应SEAC-EGOC超复合物的结构和功能

Tafur, Lucas; Bonadei, Lenny; Zheng, Yiqiang; Gabus, Caroline; Loewith, Robbie

Limited proteolysis-coupled mass spectrometry captures proteome-wide protein structural alterations and biomolecular condensation in living cells

有限蛋白水解偶联质谱法可捕获活细胞中蛋白质组范围内的蛋白质结构改变和生物分子凝聚现象。

Elsässer, Franziska; Florea, Roberta; Räsch, Felix; Zedan, Mostafa; Sen, Nesli-Ece; Pflästerer, Tim; Kleele, Tatjana; Loewith, Robbie; Weis, Karsten; de Souza, Natalie; Picotti, Paola

A dynamic feedback loop between retrograde sterol transport and TORC2 controls adaptation of the plasma membrane to stress

逆行甾醇转运与TORC2之间的动态反馈回路控制着质膜对压力的适应。

Tettamanti, Maria G; Nowak, Paulina; Kusmider, Beata; Kefauver, Jennifer M; Mercier, Vincent; Roux, Aurélien; Loewith, Robbie

A global genetic interaction map of a human cell reveals conserved principles of genetic networks

人类细胞的全局基因相互作用图谱揭示了基因网络的保守原则

Billmann, Maximilian; Costanzo, Michael; Zhang, Xiang; Hassan, Arshia Z; Rahman, Mahfuzur; Brown, Kevin R; Chan, Katherine S; Tong, Amy Hin Yan; Pons, Carles; Ward, Henry N; Ross, Catherine; van Leeuwen, Jolanda; Aregger, Michael; Lawson, Keith A; Mair, Barbara; Roth, Amy F; Sen, Nesli E; Forster, Duncan; Tan, Guihong; Mero, Patricia; Masud, Sanna N; Lee, Yoonkyu; Aguilera-Uribe, Magali; Usaj, Matej; Almeida, Sylvia M T; Aulakh, Kamaldeep; Bhojoo, Urvi; Birkadze, Saba; Budijono, Nathaniel; Cai, Xunhui; Caumanns, Joseph J; Chandrashekhar, Megha; Chang, Daniel; Climie, Ryan; Dasgupta, Kuheli; Drazic, Adrian; Rojas Echenique, Jose I; Gacesa, Rafael; Granda Farias, Adrian; Habsid, Andrea; Horecka, Ira; Kantautas, Kristin; Ji, Fenghu; Kim, Dae-Kyum; Lee, Seon Yong; Liang, Wendy; Lim, Julianne; Lin, Kevin; Lu, Xueibing; Nami, Babak; Nixon, Allison; Mikolajewicz, Nicholas; Nedyalkova, Lyudmila; Rohde, Thomas; Sartori Rodrigues, Maria; Soste, Martin; Schultz, Eric; Wang, Wen; Seetharaman, Ashwin; Shuteriqi, Emira; Sizova, Olga; Thomson Taylor, David; Tereshchenko, Maria; Tieu, David; Turowec, Jacob; Ubhi, Tajinder; Varland, Sylvia; Wang, Kyle E; Wang, Zi Yang; Wei, Jiarun; Xiao, Yu-Xi; Brown, Grant W; Cravatt, Benjamin F; Dixon, Scott J; Wyatt, Haley D M; Röst, Hannes L; Roth, Frederick P; Xia, Tian; Bader, Gary D; Loewith, Robbie; Davis, Nicholas G; Andrews, Brenda; Myers, Chad L; Moffat, Jason; Boone, Charles

Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain

近乎天然的拉伸敏感膜微区的冷冻电镜结构

Jennifer M Kefauver ,Markku Hakala ,Luoming Zou ,Josephine Alba ,Javier Espadas ,Maria G Tettamanti ,Jelena Gajić ,Caroline Gabus ,Pablo Campomanes ,Leandro F Estrozi ,Nesli E Sen ,Stefano Vanni ,Aurélien Roux ,Ambroise Desfosses ,Robbie Loewith

Small Molecule Modulator of the mTORC2 Pathway Discovered from a DEL Library Designed to Bind to Pleckstrin Homology Domains

从DEL文库中发现的mTORC2通路小分子调节剂,该文库旨在与Pleckstrin同源结构域结合

Arthur Gonse ,Jelena Gajić ,Jean-Pierre Daguer ,Sofia Barluenga ,Robbie Loewith ,Nicolas Winssinger

Dynamic metabolome profiling uncovers potential TOR signaling genes

动态代谢组分析揭示潜在的 TOR 信号基因

Stella Reichling, Peter F Doubleday, Tomas Germade, Ariane Bergmann, Robbie Loewith, Uwe Sauer, Duncan Holbrook-Smith

Cryo-EM structure of the SEA complex

SEA 复合物的低温电子显微镜结构

Lucas Tafur, Kerstin Hinterndorfer, Caroline Gabus, Chiara Lamanna, Ariane Bergmann, Yashar Sadian, Farzad Hamdi, Fotis L Kyrilis, Panagiotis L Kastritis, Robbie Loewith

Ultrastructure expansion microscopy reveals the cellular architecture of budding and fission yeast

超微结构扩展显微镜揭示了芽殖酵母和裂殖酵母的细胞结构

Kerstin Hinterndorfer, Marine H Laporte, Felix Mikus, Lucas Tafur, Clélia Bourgoint, Manoel Prouteau, Gautam Dey, Robbie Loewith, Paul Guichard, Virginie Hamel

Identification of a Covalent Importin-5 Inhibitor, Goyazensolide, from a Collective Synthesis of Furanoheliangolides

通过呋喃杂环己烷内酯的集体合成鉴定出共价型 Importin-5 抑制剂 Goyazensolide

Liu, Weilong; Patouret, Rémi; Barluenga, Sofia; Plank, Michael; Loewith, Robbie; Winssinger, Nicolas