日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Development and Characterization of a Next-Generation Oncolytic Virus Armed with an Anti-PD-1 sdAb for Osteosarcoma Treatment In Vitro

携带抗 PD-1 sdAb 的下一代溶瘤病毒的开发和表征,用于体外治疗骨肉瘤

Theresa A Higgins, Daniel J Patton, Isabella M Shimko-Lofano, Timothy L Eller, Roberto Molinari, Maninder Sandey, Aliaa Ismail, Bruce F Smith, Payal Agarwal

Area Wide Monitoring of Plant and Honey Bee (Apis mellifera) Viruses in Blueberry (Vaccinium corymbosum) Agroecosystems Facilitated by Honey Bee Pollination

通过蜜蜂授粉对蓝莓 (Vaccinium corymbosum) 农业生态系统中的植物和蜜蜂 (Apis mellifera) 病毒进行大面积监测

Eunseo Lee, Raj Vansia, James Phelan, Andrea Lofano, Adam Smith, Aiming Wang, Guillaume J Bilodeau, Stephen F Pernal, M Marta Guarna, Michael Rott, Jonathan S Griffiths

A self-amplifying mRNA SARS-CoV-2 vaccine candidate induces safe and robust protective immunity in preclinical models

一种具有自扩增能力的mRNA SARS-CoV-2候选疫苗在临床前模型中诱导了安全有效的保护性免疫。

Maruggi, Giulietta; Mallett, Corey P; Westerbeck, Jason W; Chen, Tiffany; Lofano, Giuseppe; Friedrich, Kristian; Qu, Lin; Sun, Jennifer Tong; McAuliffe, Josie; Kanitkar, Amey; Arrildt, Kathryn T; Wang, Kai-Fen; McBee, Ian; McCoy, Deborah; Terry, Rebecca; Rowles, Alison; Abrahim, Maia Araujo; Ringenberg, Michael A; Gains, Malcolm J; Spickler, Catherine; Xie, Xuping; Zou, Jing; Shi, Pei-Yong; Dutt, Taru; Henao-Tamayo, Marcela; Ragan, Izabela; Bowen, Richard A; Johnson, Russell; Nuti, Sandra; Luisi, Kate; Ulmer, Jeffrey B; Steff, Ann-Muriel; Jalah, Rashmi; Bertholet, Sylvie; Stokes, Alan H; Yu, Dong

"World in motion" - emulsion adjuvants rising to meet the pandemic challenges

“世界在运转”——乳化助剂应对疫情挑战

O'Hagan, Derek T; van der Most, Robbert; Lodaya, Rushit N; Coccia, Margherita; Lofano, Giuseppe

Distinct clonal evolution of B-cells in HIV controllers with neutralizing antibody breadth

HIV 控制者体内 B 细胞的克隆进化具有显著差异,且中和抗体的广度也不同。

Deniz Cizmeci ,Giuseppe Lofano ,Evan Rossignol ,Anne-Sophie Dugast ,Dongkyoon Kim ,Guy Cavet ,Ngan Nguyen ,Yann Chong Tan ,Michael S Seaman ,Galit Alter ,Boris Julg

Literature Mining and Mechanistic Graphical Modelling to Improve mRNA Vaccine Platforms

利用文献挖掘和机制图建模改进mRNA疫苗平台

Leonardelli, Lorena; Lofano, Giuseppe; Selvaggio, Gianluca; Parolo, Silvia; Giampiccolo, Stefano; Tomasoni, Danilo; Domenici, Enrico; Priami, Corrado; Song, Haifeng; Medini, Duccio; Marchetti, Luca; Siena, Emilio

A quantitative systems pharmacology approach to support mRNA vaccine development and optimization

定量系统药理学方法支持mRNA疫苗的开发和优化

Selvaggio, Gianluca; Leonardelli, Lorena; Lofano, Giuseppe; Fresnay, Stephanie; Parolo, Silivia; Medini, Duccio; Siena, Emilio; Marchetti, Luca

Technological approaches to streamline vaccination schedules, progressing towards single-dose vaccines

采用技术手段简化疫苗接种程序,逐步实现单剂疫苗。

Lofano, Giuseppe; Mallett, Corey P; Bertholet, Sylvie; O'Hagan, Derek T

Antigen-specific antibody Fc glycosylation enhances humoral immunity via the recruitment of complement

抗原特异性抗体 Fc 糖基化通过募集补体增强体液免疫

Giuseppe Lofano, Matthew J Gorman, Ashraf S Yousif, Wen-Han Yu, Julie M Fox, Anne-Sophie Dugast, Margaret E Ackerman, Todd J Suscovich, Joshua Weiner, Dan Barouch, Hendrik Streeck, Susan Little, Davey Smith, Douglas Richman, Douglas Lauffenburger, Bruce D Walker, Michael S Diamond, Galit Alter2

Virus-driven Inflammation Is Associated With the Development of bNAbs in Spontaneous Controllers of HIV

病毒驱动的炎症与HIV自发控制者体内广谱中和抗体(bNAbs)的产生相关。

Dugast, Anne-Sophie; Arnold, Kelly; Lofano, Giuseppe; Moore, Sarah; Hoffner, Michelle; Simek, Melissa; Poignard, Pascal; Seaman, Michael; Suscovich, Todd J; Pereyra, Florencia; Walker, Bruce D; Lauffenburger, Doug; Kwon, Douglas S; Keele, Brandon F; Alter, Galit