日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Timing matters: early administration of a high-affinity antibody targeting the tau repeat domain prevents aggregation in a mouse tauopathy model

时机至关重要:在小鼠tau蛋白病模型中,早期注射靶向tau重复结构域的高亲和力抗体可预防聚集。

Penny, Lewis K; Arastoo, Mohammad; Lofthouse, Richard; Abdallah, Aya; Imoesi, Peter I; Schwab, Karima; Shiells, Helen; Melis, Valeria; Riedel, Gernot; Harrington, Charles R; Wischik, Claude M; Porter, Andrew; Palliyil, Soumya

Hydromethylthionine sustains truncated tau-dependent inflammation-lowering effects in mouse brain.

氢甲基硫氨酸在小鼠脑中维持截短的 tau 依赖性炎症降低作用

Santos Renato X, Lee Sophie H, Lofthouse Richard, Melis Valeria, Robinson Lianne, Leith Michael, Dreesen Eline, Armstrong Paul, Vorley Thomas, Goatman Elizabeth A, Hull Claire, Riedel Gernot, Wischik Claude M, Harrington Charles R

Metastasizing Ameloblastoma Mimicking Squamous Cell Carcinoma of the Lung and Harboring an AKT1 Mutation

转移性成釉细胞瘤,其临床表现酷似肺鳞状细胞癌,且携带AKT1突变

Arrich, James; Forrest, Steven; Lofthouse, Matthew; Triantafyllou, Asterios; Hunter, Keith D; Haragan, Alexander

Quantification of plasma tau species containing the proline-rich region as a biomarker in Alzheimer's disease.

血浆中含有富含脯氨酸区域的 tau 蛋白种类的定量分析,作为阿尔茨海默病的生物标志物。

Arastoo Mohammad, Penny Lewis K, Lofthouse Richard, Hitchcock Aaron, Moelders Anna, Szalma Sona, Porter Andrew, Palliyil Soumya, Harrington Charles R, Wischik Claude M

Calcium regulation of muscle spindle mechanosensory afferent function

钙调节肌肉梭机械感觉传入功能

Simon, Anna; Lofthouse, Richard A; Miti, Philip; Giuraniuc, Claudiu V; Banks, Robert W; Bewick, Guy S

Exploring the potential of geospatial mapping of emergency call data to improve ambulance services for older adults: a feasibility study in the south central region of England

探索利用紧急呼叫数据地理空间映射改善老年人救护车服务的潜力:英格兰中南部地区的可行性研究

Fogg, Carole; King, Phil; Parsons, Vivienne; Dunbar, Nicola; Woutersen, Marcel; Branson, Julia; Pocock, Helen; Jadzinski, Patryk; Lofthouse-Jones, Chloe; Walsh, Bronagh; Smith, Dianna

A pragmatic randomized controlled trial of cognitive therapy for post-traumatic stress disorder in children and adolescents exposed to multiple traumatic stressors: the DECRYPT trial

一项针对暴露于多种创伤应激源的儿童和青少年创伤后应激障碍的认知疗法实用性随机对照试验:DECRYPT试验

Meiser-Stedman, Richard; Allen, Leila; Ashford, Polly-Anna; Beeson, Ella; Byford, Sarah; Danese, Andrea; Farr, Annie; Finn, Jack; Goodall, Ben; Grainger, Lauren; Hammond, Matthew; Harmston, Rebecca; Humphrey, Ayla; King, Dorothy; Lofthouse, Katie; Mahoney-Davies, Gerwyn; Miles, Sarah; Moore, Jessica; Morant, Nicola; Robertson, Sarah; Shepstone, Lee; Sims, Erika; Stallard, Paul; Swanepoel, Annie; Trickey, David; Trigg, Katie; Vishwakarma, Ramesh; Wilson, Jon; Dalgleish, Tim; Smith, Patrick

High-affinity antibodies specific to the core region of the tau protein exhibit diagnostic and therapeutic potential for Alzheimer's disease

针对 tau 蛋白核心区域的高亲和力抗体表现出对阿尔茨海默病的诊断和治疗潜力

Mohammad Arastoo #, Lewis K Penny #, Richard Lofthouse, Aya Abdallah, Anna Abrahamsson, Pietro Marini, Valeria Melis, Gernot Riedel, Charles R Harrington, Claude M Wischik, Andrew Porter, Soumya Palliyil

Predictive models of post-traumatic stress disorder, complex post-traumatic stress disorder, depression, and anxiety in children and adolescents following a single-event trauma

单次创伤事件后儿童和青少年创伤后应激障碍、复杂性创伤后应激障碍、抑郁症和焦虑症的预测模型

Memarzia, Jessica; Lofthouse, Katie; Dalgleish, Tim; Boyle, Adrian; McKinnon, Anna; Dixon, Clare; Smith, Patrick; Meiser-Stedman, Richard

Voice hearing in young people with posttraumatic stress disorder (PTSD) following multiple trauma exposure

多次创伤暴露后患有创伤后应激障碍 (PTSD) 的年轻人的幻听

Lofthouse, Katie; Beeson, Ella; Dalgleish, Tim; Danese, Andrea; Hodgekins, Joanne; Mahoney-Davies, Gerwyn; Smith, Patrick; Stallard, Paul; Wilson, Jon; Meiser-Stedman, Richard