Pexmetinib: A Novel Dual Inhibitor of Tie2 and p38 MAPK with Efficacy in Preclinical Models of Myelodysplastic Syndromes and Acute Myeloid Leukemia
Pexmetinib：一种新型 Tie2 和 p38 MAPK 双重抑制剂，对骨髓增生异常综合征和急性髓系白血病的临床前模型有效
期刊:Cancer Research
影响因子:12.5
doi:10.1158/0008-5472.CAN-15-3062
Lohith Bachegowda #, Kerry Morrone #, Shannon L Winski #, Ioannis Mantzaris #, Matthias Bartenstein, Nandini Ramachandra, Orsi Giricz, Vineeth Sukrithan, George Nwankwo, Samira Shahnaz, Tushar Bhagat, Sanchari Bhattacharyya, Amer Assal, Aditi Shastri, Shanisha Gordon-Mitchell, Andrea Pellagatti, Jac
信号转导
肿瘤
白血病
WB
MAPK/ERK
p38 MAPK
