Lohmer相关文献与解析，生知库 | 链接生命科学的每一步

In Vitro and Clinical Evaluations of UGT1A1-, P-gp-, OATP1B1-, and BCRP-Mediated Drug-Drug Interactions of Belumosudil, a Potent ROCK2 Inhibitor.

Belumosudil（一种强效 ROCK2 抑制剂）的 UGT1A1、P-gp、OATP1B1 和 BCRP 介导的药物相互作用的体外和临床评价

期刊:Journal of Clinical Pharmacology

影响因子:2.3

doi:10.1002/jcph.70018

Schueller Olivier, Lohmer Lauren, Beck Felix, Patel Jeegar, Sahi Jasminder

Mucosal IFNλ1 mRNA-based immunomodulation effectively reduces SARS-CoV-2 induced mortality in mice

基于粘膜 IFNλ1 mRNA 的免疫调节可有效降低 SARS-CoV-2 诱导的小鼠死亡率

期刊:EMBO Reports

影响因子:6.5

doi:10.1038/s44319-024-00216-4

Anna Macht #, Yiqi Huang #, Line S Reinert #, Vincent Grass, Kristin Lohmer, Elke Tatjana Aristizabal Prada, Eveline Babel, Alexandra Semmler, Wen Zhang, Andrea Wegner, Eva Lichtenegger-Hartl, Sonja Haas, Günther Hasenpusch, Steffen Meyer, Søren R Paludan #, Andreas Pichlmair #, Carsten Rudolph #, T

A potassium channel agonist protects hearing function and promotes outer hair cell survival in a mouse model for age-related hearing loss

在老年性听力损失小鼠模型中，钾通道激动剂可保护听力功能并促进外毛细胞存活。

期刊:Cell Death & Disease

影响因子:9.6

doi:10.1038/s41419-022-04915-5

Peixoto Pinheiro, Barbara; Müller, Marcus; Bös, Michael; Guezguez, Jamil; Burnet, Michael; Tornincasa, Mara; Rizzetto, Riccardo; Rolland, Jean-Francois; Liberati, Chiara; Lohmer, Stefan; Adel, Youssef; Löwenheim, Hubert

细胞生物学

发表日期：2022

文献求助收藏

Analysis of resilience strategies and ripple effect in blockchain-coordinated supply chains: An agent-based simulation study

基于代理的仿真研究：区块链协调供应链中韧性策略及涟漪效应分析

期刊:International Journal of Production Economics

影响因子:10

doi:10.1016/j.ijpe.2020.107882

Lohmer, Jacob; Bugert, Niels; Lasch, Rainer

发表日期：2020

文献求助收藏

A Phase I, Randomized, Single‑Blind, Placebo‑Controlled, Single Ascending Dose Study of the Safety, Tolerability, and Pharmacokinetics of Subcutaneous and Oral TRV250, a G Protein-Selective Delta Receptor Agonist, in Healthy Subjects

一项 I 期随机、单盲、安慰剂对照、单次递增剂量研究，旨在评估皮下和口服 TRV250（一种 G 蛋白选择性 Delta 受体激动剂）在健康受试者中的安全性、耐受性和药代动力学。

期刊:CNS Drugs

影响因子:7.4

doi:10.1007/s40263-020-00738-0

Fossler, Michael J; Schmith, Virginia; Greene, Stephen A; Lohmer, Lauren; Kramer, Michael S; Arscott, Kelly; James, Ian E; Demitrack, Mark A

信号转导

发表日期：2020

文献求助收藏

Invasive Cell Fate Requires G1 Cell-Cycle Arrest and Histone Deacetylase-Mediated Changes in Gene Expression

侵袭性细胞命运需要G1期细胞周期阻滞和组蛋白去乙酰化酶介导的基因表达改变

期刊:Developmental Cell

影响因子:8.7

doi:10.1016/j.devcel.2015.10.002

Matus, David Q; Lohmer, Lauren L; Kelley, Laura C; Schindler, Adam J; Kohrman, Abraham Q; Barkoulas, Michalis; Zhang, Wan; Chi, Qiuyi; Sherwood, David R

Invadopodia and basement membrane invasion in vivo

体内侵袭伪足和基底膜侵袭

期刊:Cell Adhesion & Migration

影响因子:3.5

doi:10.4161/cam.28406

Lohmer, Lauren L; Kelley, Laura C; Hagedorn, Elliott J; Sherwood, David R

发表日期：2014

文献求助收藏

Epidural analgesia is not superior to systemic postoperative analgesia with regard to preventing chronic or neuropathic pain after thoracotomy

就预防开胸术后慢性疼痛或神经性疼痛而言，硬膜外镇痛并不优于全身术后镇痛。

期刊:Journal of Cardiothoracic Surgery

影响因子:1.5

doi:10.1186/1749-8090-8-127

Kampe, Sandra; Lohmer, Joachim; Weinreich, Gerhard; Hahn, Moritz; Stamatis, Georgios; Welter, Stefan

发表日期：2013

文献求助收藏

The Effect of Ecopipam on the Pharmacokinetics of Concomitant Medications

Ecopipam对合并用药药代动力学的影响

Pharmacokinetics of Belumosudil and Its Metabolites in Individuals With Hepatic Impairment

贝鲁莫舒地尔及其代谢物在肝功能受损患者体内的药代动力学

In Vitro and Clinical Evaluations of UGT1A1-, P-gp-, OATP1B1-, and BCRP-Mediated Drug-Drug Interactions of Belumosudil, a Potent ROCK2 Inhibitor.

Belumosudil（一种强效 ROCK2 抑制剂）的 UGT1A1、P-gp、OATP1B1 和 BCRP 介导的药物相互作用的体外和临床评价

Mucosal IFNλ1 mRNA-based immunomodulation effectively reduces SARS-CoV-2 induced mortality in mice

基于粘膜 IFNλ1 mRNA 的免疫调节可有效降低 SARS-CoV-2 诱导的小鼠死亡率

A potassium channel agonist protects hearing function and promotes outer hair cell survival in a mouse model for age-related hearing loss

在老年性听力损失小鼠模型中，钾通道激动剂可保护听力功能并促进外毛细胞存活。

Analysis of resilience strategies and ripple effect in blockchain-coordinated supply chains: An agent-based simulation study

基于代理的仿真研究：区块链协调供应链中韧性策略及涟漪效应分析

A Phase I, Randomized, Single‑Blind, Placebo‑Controlled, Single Ascending Dose Study of the Safety, Tolerability, and Pharmacokinetics of Subcutaneous and Oral TRV250, a G Protein-Selective Delta Receptor Agonist, in Healthy Subjects

一项 I 期随机、单盲、安慰剂对照、单次递增剂量研究，旨在评估皮下和口服 TRV250（一种 G 蛋白选择性 Delta 受体激动剂）在健康受试者中的安全性、耐受性和药代动力学。

Invasive Cell Fate Requires G1 Cell-Cycle Arrest and Histone Deacetylase-Mediated Changes in Gene Expression

侵袭性细胞命运需要G1期细胞周期阻滞和组蛋白去乙酰化酶介导的基因表达改变

Invadopodia and basement membrane invasion in vivo

体内侵袭伪足和基底膜侵袭

Epidural analgesia is not superior to systemic postoperative analgesia with regard to preventing chronic or neuropathic pain after thoracotomy

就预防开胸术后慢性疼痛或神经性疼痛而言，硬膜外镇痛并不优于全身术后镇痛。