日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CYRI-B-mediated macropinocytosis drives metastasis via lysophosphatidic acid receptor uptake

CYRI-B 介导的巨胞饮作用通过溶血磷脂酸受体摄取驱动转移

Savvas Nikolaou, Amelie Juin, Jamie A Whitelaw, Nikki R Paul, Loic Fort, Colin Nixon, Heather J Spence, Sheila Bryson, Laura M Machesky

CYRI-A limits invasive migration through macropinosome formation and integrin uptake regulation

CYRI-A 通过巨胞饮囊的形成和整合素摄取的调控来限制侵袭性迁移。

Anh Hoang Le ,Tamas Yelland ,Nikki R Paul ,Loic Fort ,Savvas Nikolaou ,Shehab Ismail ,Laura M Machesky

N-WASP Control of LPAR1 Trafficking Establishes Response to Self-Generated LPA Gradients to Promote Pancreatic Cancer Cell Metastasis

N-WASP 控制 LPAR1 运输建立对自生 LPA 梯度的反应以促进胰腺癌细胞转移

Amelie Juin, Heather J Spence, Kirsty J Martin, Ewan McGhee, Matthew Neilson, Marie F A Cutiongco, Nikolaj Gadegaard, Gillian Mackay, Loic Fort, Sergio Lilla, Gabriela Kalna, Peter Thomason, Yvette W H Koh, Jim C Norman, Robert H Insall, Laura M Machesky

Fam49/CYRI interacts with Rac1 and locally suppresses protrusions

Fam49/CYRI 与 Rac1 相互作用并局部抑制突起

Loic Fort, José Miguel Batista, Peter A Thomason, Heather J Spence, Jamie A Whitelaw, Luke Tweedy, Jennifer Greaves, Kirsty J Martin, Kurt I Anderson, Peter Brown, Sergio Lilla, Matthew P Neilson, Petra Tafelmeyer, Sara Zanivan, Shehab Ismail, David M Bryant, Nicholas C O Tomkinson, Luke H Chamberla

Loss of N-WASP drives early progression in an Apc model of intestinal tumourigenesis

N-WASP 的缺失导致 Apc 肠道肿瘤发生模型的早期进展

Hayley T Morris, Loic Fort, Heather J Spence, Rachana Patel, David F Vincent, James H Park, Scott B Snapper, Francis A Carey, Owen J Sansom, Laura M Machesky

Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency

在半胱天冬酶缺乏的情况下,线粒体通透性增加会激活NF-κB依赖的抗肿瘤活性。

Evangelos Giampazolias ,Barbara Zunino ,Sandeep Dhayade ,Florian Bock ,Catherine Cloix ,Kai Cao ,Alba Roca ,Jonathan Lopez ,Gabriel Ichim ,Emma Proïcs ,Camila Rubio-Patiño ,Loic Fort ,Nader Yatim ,Emma Woodham ,Susana Orozco ,Lucia Taraborrelli ,Nieves Peltzer ,Daniele Lecis ,Laura Machesky ,Henning Walczak ,Matthew L Albert ,Simon Milling ,Andrew Oberst ,Jean-Ehrland Ricci ,Kevin M Ryan ,Karen Blyth ,Stephen W G Tait

Gab2 phosphorylation by RSK inhibits Shp2 recruitment and cell motility

RSK 磷酸化 Gab2 可抑制 Shp2 募集和细胞运动

Xiaocui Zhang, Genevieve Lavoie, Loic Fort, Edward L Huttlin, Joseph Tcherkezian, Jacob A Galan, Haihua Gu, Steven P Gygi, Sebastien Carreno, Philippe P Roux