日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pharmacophore-guided optimization of the hit compound CTN1122 in the design of promising imidazo[1,2-a]pyrazine derivatives targeting the casein kinase 1 for antileishmanial therapy.

在设计靶向酪蛋白激酶 1 的有前景的咪唑并[1,2-a]吡嗪衍生物以进行抗利什曼原虫治疗时,以药效团为指导对先导化合物 CTN1122 进行优化

Tisseur Lhana, Logé Cédric, Cojean Sandrine, Gassama Khadidiatou, Karcher Lilian, Pagniez Fabrice, Cavé Christian, Bernadat Guillaume, Loiseau Philippe M, Bach Stéphane, Thiéfaine Jérôme, Bonnet Justine, Picot Carine, Tomasoni Christophe, Leclercq Olivier, Baratte Blandine, Robert Thomas, Le Pape Patrice, Rachidi Najma, Bazin Marc-Antoine, Marchand Pascal

Effect of Phlebotomus papatasi on the fitness, infectivity and antimony-resistance phenotype of antimony-resistant Leishmania major Mon-25

白蛉对锑耐药利什曼原虫Mon-25的适应性、感染性和锑耐药表型的影响

Mekarnia, Nalia; Benallal, Kamal-Eddine; Sádlová, Jovana; Vojtková, Barbora; Mauras, Aurélie; Imbert, Nicolas; Longhitano, Maryline; Harrat, Zoubir; Volf, Petr; Loiseau, Philippe M; Cojean, Sandrine

Supramolecular assemblies from antimony(V) complexes for the treatment of leishmaniasis

利用锑(V)配合物超分子组装体治疗利什曼病

Demicheli, Cynthia; Vallejos, Virgínia M R; Lanza, Juliane S; Ramos, Guilherme S; Do Prado, Bruno R; Pomel, Sébastien; Loiseau, Philippe M; Frézard, Frédéric

The Potential of 2-Substituted Quinolines as Antileishmanial Drug Candidates

2-取代喹啉作为抗利什曼原虫候选药物的潜力

Loiseau, Philippe M; Balaraman, Kaluvu; Barratt, Gillian; Pomel, Sébastien; Durand, Rémy; Frézard, Frédéric; Figadère, Bruno

Stimulation of Acanthamoeba castellanii excystment by enzyme treatment and consequences on trophozoite growth

酶处理刺激棘阿米巴脱囊及其对滋养体生长的影响

Fechtali-Moute, Zineb; Loiseau, Philippe M; Pomel, Sébastien

Intranasal vaccine from whole Leishmania donovani antigens provides protection and induces specific immune response against visceral leishmaniasis

由全利什曼原虫抗原制成的鼻内疫苗可提供保护并诱导针对内脏利什曼病的特异性免疫反应。

Helou, Doumet Georges; Mauras, Aurélie; Fasquelle, François; Lanza, Juliane Sousa; Loiseau, Philippe M; Betbeder, Didier; Cojean, Sandrine

Drugs used for the treatment of cerebral and disseminated infections caused by free-living amoebae

用于治疗由自由生活阿米巴引起的脑部和播散性感染的药物

Taravaud, Alexandre; Fechtali-Moute, Zineb; Loiseau, Philippe M; Pomel, Sébastien

Repurposing Auranofin and Evaluation of a New Gold(I) Compound for the Search of Treatment of Human and Cattle Parasitic Diseases: From Protozoa to Helminth Infections

重新利用金诺芬并评估一种新的金(I)化合物在治疗人类和牛寄生虫病中的应用:从原生动物到蠕虫感染

Feng, Liwen; Pomel, Sébastien; Latre de Late, Perle; Taravaud, Alexandre; Loiseau, Philippe M; Maes, Louis; Cho-Ngwa, Fidelis; Bulman, Christina A; Fischer, Chelsea; Sakanari, Judy A; Ziniel, Peter D; Williams, David L; Davioud-Charvet, Elisabeth

GDP-Mannose Pyrophosphorylase: A Biologically Validated Target for Drug Development Against Leishmaniasis

GDP-甘露糖焦磷酸化酶:一种经生物学验证的利什曼病药物研发靶点

Pomel, Sébastien; Mao, Wei; Ha-Duong, Tâp; Cavé, Christian; Loiseau, Philippe M

Virtual screen for repurposing approved and experimental drugs for candidate inhibitors of EBOLA virus infection

利用虚拟筛选方法,从已批准和实验性药物中筛选出埃博拉病毒感染的候选抑制剂。

Veljkovic, Veljko; Loiseau, Philippe M; Figadere, Bruno; Glisic, Sanja; Veljkovic, Nevena; Perovic, Vladimir R; Cavanaugh, David P; Branch, Donald R