日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Design and Synthesis of 4-Arylazo Pyrazole Carboxamides as Dual AChE/BChE Inhibitors: Kinetic and In Silico Evaluation

4-芳基偶氮吡唑甲酰胺类化合物作为双重AChE/BChE抑制剂的设计与合成：动力学和计算机模拟评价

期刊:Pharmaceuticals
影响因子:4.8
doi:10.3390/ph19020239
Akocak, Suleyman; Lolak, Nebih; Duran, Hatice Esra; Demir Çetinkaya, Büşra; Hashem, Hamada; Bräse, Stefan; Türkeş, Cüneyt
发表日期：2026
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Isovanillin-derived bis-hydrazones as dual cholinesterase and carbonic anhydrase inhibitors: synthesis, enzymatic profiling, and computational insights from molecular docking and dynamics

异香草醛衍生的双腙作为胆碱酯酶和碳酸酐酶双重抑制剂：合成、酶学分析以及分子对接和动力学计算见解

期刊:Future Medicinal Chemistry
影响因子:3.4
doi:10.1080/17568919.2026.2617608
Türkeş, Cüneyt; Yapar, Gönül; Duran, Hatice Esra; Lolak, Nebih; Akocak, Suleyman
发表日期：2026
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Investigating the Anti-Inflammatory Potential of SLC-0111: A Carbonic Anhydrase Inhibitor Targeting Cyclooxygenase-Mediated Inflammatory Pathways in a Carrageenan-Induced Rat Model

研究SLC-0111的抗炎潜力：一种靶向环氧合酶介导的炎症通路的碳酸酐酶抑制剂，以角叉菜胶诱导的大鼠模型为模型

期刊:Journal of Biochemical and Molecular Toxicology
影响因子:2.8
doi:10.1002/jbt.70217
Doğan, Aslınur; Yanılmaz, Elif Merve Betül; Karakoc, Gulcin; Parlar, Ali; Annaç, Ebru; Lolak, Nebih; Akocak, Suleyman
信号转导
炎症/感染
Rat
炎症
发表日期：2025
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Sulfonamide-Bearing Pyrazolone Derivatives as Multitarget Therapeutic Agents: Design, Synthesis, Characterization, Biological Evaluation, In Silico ADME/T Profiling and Molecular Docking Study

磺酰胺基吡唑酮衍生物作为多靶点治疗剂：设计、合成、表征、生物学评价、计算机模拟ADME/T分析和分子对接研究

期刊:Pharmacology Research & Perspectives
影响因子:2.3
doi:10.1002/prp2.70088
Lolak, Nebih; Akocak, Suleyman; Topal, Meryem; Koçyiğit, Ümit Muhammet; Işık, Mesut; Türkeş, Cüneyt; Topal, Fevzi; Durgun, Mustafa; Beydemir, Şükrü
发表日期：2025
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Application of Dragonnet and Conformal Inference for Estimating Individualized Treatment Effects for Personalized Stroke Prevention: Retrospective Cohort Study

利用 Dragonnet 和共形推断估计个体化卒中预防治疗效果：回顾性队列研究

期刊:JMIR Cardio
影响因子:2.2
doi:10.2196/50627
Lolak, Sermkiat; Attia, John; McKay, Gareth J; Thakkinstian, Ammarin
发表日期：2025
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Comparing Explainable Machine Learning Approaches With Traditional Statistical Methods for Evaluating Stroke Risk Models: Retrospective Cohort Study

比较可解释机器学习方法与传统统计方法在评估卒中风险模型方面的差异：回顾性队列研究

期刊:JMIR Cardio
影响因子:2.2
doi:10.2196/47736
Lolak, Sermkiat; Attia, John; McKay, Gareth J; Thakkinstian, Ammarin
中风
心血管
发表日期：2023
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Sulphonamides incorporating 1,3,5-triazine structural motifs show antioxidant, acetylcholinesterase, butyrylcholinesterase, and tyrosinase inhibitory profile

含有 1,3,5-三嗪结构基序的磺胺类药物具有抗氧化、乙酰胆碱酯酶、丁酰胆碱酯酶和酪氨酸酶抑制作用

期刊:Journal of Enzyme Inhibition and Medicinal Chemistry
影响因子:5.6
doi:10.1080/14756366.2019.1707196
Nabih Lolak, Mehmet Boga, Muhammed Tuneg, Gulcin Karakoc, Suleyman Akocak, Claudiu T Supuran
信号转导
发表日期：2020
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Synthesis of calix[4]azacrown substituted sulphonamides with antioxidant, acetylcholinesterase, butyrylcholinesterase, tyrosinase and carbonic anhydrase inhibitory action

合成具有抗氧化、抑制乙酰胆碱酯酶、丁酰胆碱酯酶、酪氨酸酶和碳酸酐酶活性的杯[4]氮杂冠醚取代磺酰胺

期刊:Journal of Enzyme Inhibition and Medicinal Chemistry
影响因子:5.4
doi:10.1080/14756366.2020.1765166
Oguz, Mehmet; Kalay, Erbay; Akocak, Suleyman; Nocentini, Alessio; Lolak, Nebih; Boga, Mehmet; Yilmaz, Mustafa; Supuran, Claudiu T
发表日期：2020
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Synthesis and cytotoxic activities of novel copper and silver complexes of 1,3-diaryltriazene-substituted sulfonamides

1,3-二芳基三氮烯取代磺酰胺新型铜和银配合物的合成及细胞毒活性

期刊:Journal of Enzyme Inhibition and Medicinal Chemistry
影响因子:5.6
doi:10.1080/14756366.2018.1530994
Dilek Canakci, Ismail Koyuncu, Nabih Lolak, Mustafa Durgun, Suleyman Akocak, Claudiu T Supuran
免疫
细胞生物学
其它细胞
发表日期：2019
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