日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Assessing Effects of BHV-0223 40 mg Zydis Sublingual Formulation and Riluzole 50 mg Oral Tablet on Liver Function Test Parameters Utilizing DILIsym

利用 DILIsym 评估 BHV-0223 40 mg Zydis 舌下制剂和利鲁唑 50 mg 口服片剂对肝功能检测参数的影响

Longo, Diane M; Shoda, Lisl K M; Howell, Brett A; Coric, Vladimir; Berman, Robert M; Qureshi, Irfan A

Quantitative Systems Toxicology Analysis of In Vitro Mechanistic Assays Reveals Importance of Bile Acid Accumulation and Mitochondrial Dysfunction in TAK-875-Induced Liver Injury

体外机制试验的定量系统毒理学分析揭示了胆汁酸积累和线粒体功能障碍在TAK-875诱导的肝损伤中的重要性

Longo, Diane M; Woodhead, Jeffrey L; Walker, Paul; Herédi-Szabó, Krisztina; Mogyorósi, Károly; Wolenski, Francis S; Dragan, Yvonne P; Mosedale, Merrie; Siler, Scott Q; Watkins, Paul B; Howell, Brett A

High-dimensional analysis of the aging immune system: verification of age-associated differences in immune signaling responses in healthy donors

衰老免疫系统的高维分析:验证健康供体中与年龄相关的免疫信号反应差异

Longo, Diane M; Louie, Brent; Ptacek, Jason; Friedland, Greg; Evensen, Erik; Putta, Santosh; Atallah, Michelle; Spellmeyer, David; Wang, Ena; Pos, Zoltan; Marincola, Francesco M; Schaeffer, Andrea; Lukac, Suzanne; Railkar, Radha; Beals, Chan R; Cesano, Alessandra; Carayannopoulos, Leonidas N; Hawtin, Rachael E

Single-cell network profiling of peripheral blood mononuclear cells from healthy donors reveals age- and race-associated differences in immune signaling pathway activation.

对健康供体外周血单核细胞的单细胞网络分析揭示了免疫信号通路激活中与年龄和种族相关的差异

Longo Diane M, Louie Brent, Putta Santosh, Evensen Erik, Ptacek Jason, Cordeiro James, Wang Ena, Pos Zoltan, Hawtin Rachael E, Marincola Francesco M, Cesano Alessandra