日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mechanisms of HSV-1 helicase-primase inhibition and replication fork complex assembly

HSV-1解旋酶-引物酶抑制和复制叉复合物组装的机制

Yu, Zishuo; Sathyanarayana, Pradeep; Liu, Cong; Tan, Joel M J; Yang, Pan; Das, Biswajit; Hu, Side; Fan, Xiaoyi; Ji, Chenggong; Weller, Sandra K; Shekhar, Mrinal; Coen, Donald M; Kranzusch, Philip J; Loparo, Joseph J; Abraham, Jonathan

DNA polymerase λ autoinhibition is relieved via Ku interaction during non-homologous end joining

在非同源末端连接过程中,DNA聚合酶λ的自身抑制作用通过Ku蛋白的相互作用得到解除。

Case, Brandon C; Scoccia, Leonardo; Zhao, Zhihan; Loparo, Joseph J

Designing life science assessments in the era of generative artificial intelligence

在生成式人工智能时代设计生命科学评估

Kwong, Andrew C; Magnano, Christopher; DeOliveira, Cristina; Goglia, Christine; Loparo, Joseph J; Peters, John Jacob

The hit-and-run of cell wall synthesis: LpoB transiently binds and activates PBP1b through a conserved allosteric switch

细胞壁合成的“速战速决”:LpoB 通过保守的变构开关瞬时结合并激活 PBP1b。

Shlosman, Irina; Vettiger, Andrea; Bernhardt, Thomas G; Kruse, Andrew C; Loparo, Joseph J

Conformational regulation of two essential activators of bacterial cell elongation

细菌细胞伸长两个关键激活因子的构象调控

Gilman, Morgan S A; Shlosman, Irina; Guerra, Daniel D Samé; Domecillo, Masy; Fivenson, Elayne M; Bourett, Claire; Bernhardt, Thomas G; Polizzi, Nicholas F; Loparo, Joseph J; Kruse, Andrew C

A bipartite interaction with the processivity clamp potentiates Pol IV-mediated TLS.

与过程钳的双向相互作用增强了 Pol IV 介导的 TLS

Chang Seungwoo, Laureti Luisa, Thrall Elizabeth S, Kay Marguerite S, Philippin Gaëlle, Jergic Slobodan, Pagès Vincent, Loparo Joseph J

The NHEJ machinery is translocated off DNA ends to enable resection

非同源末端连接(NHEJ)机制从DNA末端转移,从而实现切除。

Sathyanarayana, Pradeep; Wu, Yufan; Walter, Johannes C; Loparo, Joseph J

Structural role for DNA Ligase IV in promoting the fidelity of non-homologous end joining

DNA连接酶IV在促进非同源末端连接的保真性方面发挥结构作用

Stinson, Benjamin M; Carney, Sean M; Walter, Johannes C; Loparo, Joseph J

Allosteric activation of cell wall synthesis during bacterial growth

细菌生长过程中细胞壁合成的变构激活

Shlosman, Irina; Fivenson, Elayne M; Gilman, Morgan S A; Sisley, Tyler A; Walker, Suzanne; Bernhardt, Thomas G; Kruse, Andrew C; Loparo, Joseph J

Holding it together: DNA end synapsis during non-homologous end joining

维持连接:非同源末端连接过程中的DNA末端联会

Loparo, Joseph J