日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PROTAC-Mediated Degradation of TAF1 Induces Apoptosis in AML Cells and Inhibits Tumor Growth In Vivo.

PROTAC介导的TAF1降解诱导AML细胞凋亡并抑制体内肿瘤生长

Chen Lihong, Shultz Zachary P, Sansone Marianna, Fang Bin, Liu Xiang, Teng Mingxiang, Schonbrunn Ernst, Lopchuk Justin M, Chen Jiandong

Asymmetric synthesis of sulfoximines, sulfonimidoyl fluorides and sulfonimidamides enabled by an enantiopure bifunctional S(VI) reagent

利用对映体纯的双功能S(VI)试剂实现亚砜亚胺、磺酰亚胺氟化物和磺酰亚胺的不对称合成

Teng, Shun; Shultz, Zachary P; Shan, Chuan; Wojtas, Lukasz; Lopchuk, Justin M

Strain-release driven reactivity of a chiral SuFEx reagent provides stereocontrolled access to sulfinamides, sulfonimidamides, and sulfoximines

手性 SuFEx 试剂的应变释放驱动反应活性可实现对亚磺酰胺、磺酰亚胺酰胺和亚砜亚胺的立体选择性合成。

Athawale, Paresh R; Shultz, Zachary P; Saputo, Alexandra; Hall, Yvonne D; Lopchuk, Justin M

Regioselective hydroamination of unactivated olefins with diazirines as a diversifiable nitrogen source

以二氮杂环丙烯为可多样化氮源,对未活化烯烃进行区域选择性氢胺化反应

Xing, Qingyu; Chandrachud, Preeti P; Tillett, Khalilia; Lopchuk, Justin M

Divergent synthesis of complex withanolides enabled by a scalable route and late-stage functionalization

通过可扩展的合成路线和后期功能化实现复杂茄内酯的发散合成

Che, Wen; Wojitas, Lukasz; Shan, Chuan; Lopchuk, Justin M

Direct catalytic photodecarboxylative amination of carboxylic acids with diazirines for divergent access to nitrogen-containing compounds

利用重氮丙烯直接催化光脱羧胺化羧酸,可获得多种含氮化合物。

Maharaj, Vishala; Athawale, Paresh R; Chandrachud, Preeti P; Lopchuk, Justin M

Stereospecific α-(hetero)arylation of sulfoximines and sulfonimidamides

亚砜亚胺和磺酰亚胺的立体选择性α-(杂)芳基化

Shultz, Zachary P; Scattolin, Thomas; Wojtas, Lukasz; Lopchuk, Justin M

Organic chemistry. Strain-release amination

有机化学。应变释放胺化反应

Gianatassio, Ryan; Lopchuk, Justin M; Wang, Jie; Pan, Chung-Mao; Malins, Lara R; Prieto, Liher; Brandt, Thomas A; Collins, Michael R; Gallego, Gary M; Sach, Neal W; Spangler, Jillian E; Zhu, Huichin; Zhu, Jinjiang; Baran, Phil S

Methyl 1-benzyl-5-methyl-2,4-diphenyl-1H-pyrrole-3-carboxyl-ate

1-苄基-5-甲基-2,4-二苯基-1H-吡咯-3-羧酸甲酯

Lopchuk, Justin M; Gribble, Gordon W; Jasinski, Jerry P

Bruceolline D: 3,3-dimethyl-1H,4H-cyclo-penta-[b]indol-2(3H)-one

布鲁西林 D:3,3-二甲基-1H,4H-环戊并[b]吲哚-2(3H)-酮

Lopchuk, Justin M; Gribble, Gordon W; Jasinski, Jerry P