日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Bridging GWAS to genes: an integrative multi-omics approach using cattle data

将全基因组关联分析与基因联系起来:一种利用牛数据的整合多组学方法

Ghoreishifar, Mohammad; Macleod, Iona M; Nguyen, Tuan; Lopdell, Thomas J; Littlejohn, Mathew D; Xiang, Ruidong; Chamberlain, Amanda J; Pryce, Jennie E; Goddard, Michael E

Fine mapping highlights ITGAL and MUS81 loss‐of‐function mutations modulating recessive impacts in dairy cattle

精细定位突显了ITGAL和MUS81功能缺失突变对奶牛隐性遗传影响的调节作用。

Seidizadeh, Omid; Cairo, Andrea; Mancini, Ilaria; George, James N; Peyvandi, Flora; Duntsch, Laura; Jivanji, Swati; Lopdell, Thomas; Reynolds, Edwardo G M; Williams, Liam; Littlejohn, Mathew D

An integrative approach to prioritize candidate causal genes for complex traits in cattle

一种用于确定牛复杂性状候选致病基因优先级的综合方法

Ghoreishifar, Mohammad; Macleod, Iona M; Chamberlain, Amanda J; Liu, Zhiqian; Lopdell, Thomas J; Littlejohn, Mathew D; Xiang, Ruidong; Pryce, Jennie E; Goddard, Michael E

Comparison of genomic prediction accuracies in dairy cattle lactation traits using five classes of functional variants versus generic SNP

利用五类功能变异与通用SNP比较基因组预测奶牛泌乳性状的准确性

Alemu, Setegn Worku; Lopdell, Thomas J; Trevarton, Alexander J; Snell, Russell G; Littlejohn, Mathew D; Garrick, Dorian J

Survey of functional Mendelian variants in New Zealand Huntaway and Heading dog breeds

新西兰猎犬和牧羊犬品种的功能性孟德尔变异调查

Smith, Florence; Lopdell, Thomas; Stephen, Melissa; Henry, Millicent; Dittmer, Keren; Hunt, Hayley; Sneddon, Nick; Williams, Liam; Rolfe, Jack; Garrick, Dorian; Littlejohn, Mathew D

Fine mapping highlights ITGAL and MUS81 loss‐of‐function mutations modulating recessive impacts in dairy cattle

精细定位突显了ITGAL和MUS81功能缺失突变对奶牛隐性遗传影响的调节作用。

Kishita, Kenji; Washiyama, Naoki; Takeuchi, Yuki; Hirano, Masahiro; Yamanaka, Ken; Ohashi, Yuko; Tsuda, Kazumasa; Okamoto, Kazuma; Duntsch, Laura; Jivanji, Swati; Lopdell, Thomas; Reynolds, Edwardo G M; Williams, Liam; Littlejohn, Mathew D

A common regulatory haplotype doubles lactoferrin concentration in milk

一种常见的调控单倍型可使牛奶中乳铁蛋白浓度增加一倍

Lopdell, Thomas J; Trevarton, Alexander J; Moody, Janelle; Prowse-Wilkins, Claire; Knowles, Sarah; Tiplady, Kathryn; Chamberlain, Amanda J; Goddard, Michael E; Spelman, Richard J; Lehnert, Klaus; Snell, Russell G; Davis, Stephen R; Littlejohn, Mathew D

An organism-wide ATAC-seq peak catalog for the bovine and its use to identify regulatory variants

牛的全生物体 ATAC-seq 峰目录及其在识别调控变异中的应用

Can Yuan, Lijing Tang, Thomas Lopdell, Vyacheslav A Petrov, Claire Oget-Ebrad, Gabriel Costa Monteiro Moreira, José Luis Gualdrón Duarte, Arnaud Sartelet, Zhangrui Cheng, Mazdak Salavati, D Claire Wathes, Mark A Crowe; GplusE Consortium; Wouter Coppieters, Mathew Littlejohn, Carole Charlier, Tom Dru

Successful editing and maintenance of lactogenic gene expression in primary bovine mammary epithelial cells

成功编辑并维持原代牛乳腺上皮细胞中泌乳基因的表达

Moody, Janelle; Mears, Emily; Trevarton, Alexander J; Broadhurst, Marita; Molenaar, Adrian; Chometon, Thaize; Lopdell, Thomas; Littlejohn, Matthew; Snell, Russell

Genetic variation in histone modifications and gene expression identifies regulatory variants in the mammary gland of cattle

组蛋白修饰和基因表达的遗传变异可识别牛乳腺中的调控变异。

Prowse-Wilkins, Claire P; Lopdell, Thomas J; Xiang, Ruidong; Vander Jagt, Christy J; Littlejohn, Mathew D; Chamberlain, Amanda J; Goddard, Michael E