日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Attenuation of Nicotine Effects on A549 Lung Cancer Cells by Synthetic α7 nAChR Antagonists APS7-2 and APS8-2

合成 α7 nAChR 拮抗剂 APS7-2 和 APS8-2 减弱尼古丁对 A549 肺癌细胞的影响

期刊:Marine Drugs
影响因子:4.9
doi:10.3390/md22040147
Ahmad Joukhan, Veno Kononenko, Tadeja Bele, Marija Sollner Dolenc, Steve Peigneur, Ernesto Lopes Pinheiro-Junior, Jan Tytgat, Tom Turk, Igor Križaj, Damjana Drobne
免疫
细胞生物学
肺癌
肿瘤细胞
发表日期：2024
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Diversely evolved xibalbin variants from remipede venom inhibit potassium channels and activate PKA-II and Erk1/2 signaling

来自陆行蛇毒液的多种进化的 xibalbin 变体可抑制钾通道并激活 PKA-II 和 Erk1/2 信号传导

期刊:BMC Biology
影响因子:4.4
doi:10.1186/s12915-024-01955-5
Ernesto Lopes Pinheiro-Junior #, Ehsan Alirahimi #, Steve Peigneur, Jörg Isensee, Susanne Schiffmann, Pelin Erkoc, Robert Fürst, Andreas Vilcinskas, Tobias Sennoner, Ivan Koludarov, Benjamin-Florian Hempel, Jan Tytgat, Tim Hucho, Björn M von Reumont0
信号转导
MAPK/ERK
发表日期：2024
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AsKC11, a Kunitz Peptide from Anemonia sulcata, Is a Novel Activator of G Protein-Coupled Inward-Rectifier Potassium Channels

AsKC11 是一种来自海葵的 Kunitz 肽，是一种新型的 G 蛋白偶联内向整流钾通道激活剂

期刊:Marine Drugs
影响因子:4.9
doi:10.3390/md20020140
Dongchen An, Ernesto Lopes Pinheiro-Junior, László Béress, Irina Gladkikh, Elena Leychenko, Eivind A B Undheim, Steve Peigneur, Jan Tytgat
发表日期：2022
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New Diarylamine KV10.1 Inhibitors and Their Anticancer Potential

新型二芳胺 KV10.1 抑制剂及其抗癌潜力

期刊:Pharmaceutics
影响因子:4.9
doi:10.3390/pharmaceutics14091963
Špela Gubič, Žan Toplak, Xiaoyi Shi, Jaka Dernovšek, Louise Antonia Hendrickx, Ernesto Lopes Pinheiro-Junior, Steve Peigneur, Jan Tytgat, Luis A Pardo, Lucija Peterlin Mašič, Tihomir Tomašič
肿瘤
发表日期：2022
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Apamin structure and pharmacology revisited

蜂毒明结构与药理学再探

期刊:Frontiers in Pharmacology
影响因子:4.4
doi:10.3389/fphar.2022.977440
Alexey I Kuzmenkov, Steve Peigneur, Joshua A Nasburg, Konstantin S Mineev, Maxim V Nikolaev, Ernesto Lopes Pinheiro-Junior, Alexander S Arseniev, Heike Wulff, Jan Tytgat, Alexander A Vassilevski
发表日期：2022
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Nicotinic Acetylcholine Receptors Are Novel Targets of APETx-like Toxins from the Sea Anemone Heteractis magnifica

烟碱乙酰胆碱受体是海葵 Heteractis magnifica 中 APETx 样毒素的新靶点

期刊:Toxins
影响因子:
doi:10.3390/toxins14100697
Rimma S Kalina, Igor E Kasheverov, Sergey G Koshelev, Oksana V Sintsova, Steve Peigneur, Ernesto Lopes Pinheiro-Junior, Roman S Popov, Victoria E Chausova, Margarita M Monastyrnaya, Pavel S Dmitrenok, Marina P Isaeva, Jan Tytgat, Sergey A Kozlov, Emma P Kozlovskaya, Elena V Leychenko, Irina N Gladki
信号转导
发表日期：2022
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Design of New Potent and Selective Thiophene-Based KV1.3 Inhibitors and Their Potential for Anticancer Activity

新型强效选择性噻吩基 KV1.3 抑制剂的设计及其抗癌活性潜力

期刊:Cancers
影响因子:
doi:10.3390/cancers14112595
Špela Gubič, Louise Antonia Hendrickx, Xiaoyi Shi, Žan Toplak, Štefan Možina, Kenny M Van Theemsche, Ernesto Lopes Pinheiro-Junior, Steve Peigneur, Alain J Labro, Luis A Pardo, Jan Tytgat, Tihomir Tomašič, Lucija Peterlin Mašič
肿瘤
发表日期：2022
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Kunitz-Type Peptides from the Sea Anemone Heteractis crispa Demonstrate Potassium Channel Blocking and Anti-Inflammatory Activities

来自海葵Heteractis crispa的Kunitz型肽表现出钾通道阻断和抗炎活性

期刊:Biomedicines
影响因子:3.9
doi:10.3390/biomedicines8110473
Gladkikh, Irina; Peigneur, Steve; Sintsova, Oksana; Lopes Pinheiro-Junior, Ernesto; Klimovich, Anna; Menshov, Alexander; Kalinovsky, Anatoly; Isaeva, Marina; Monastyrnaya, Margarita; Kozlovskaya, Emma; Tytgat, Jan; Leychenko, Elena
发表日期：2020
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Beyond hemostasis: a snake venom serine protease with potassium channel blocking and potential antitumor activities

超越止血：具有钾通道阻断和潜在抗肿瘤活性的蛇毒丝氨酸蛋白酶

期刊:Scientific Reports
影响因子:3.8
doi:10.1038/s41598-020-61258-x
Johara Boldrini-França #, Ernesto Lopes Pinheiro-Junior #, Steve Peigneur, Manuela Berto Pucca, Felipe Augusto Cerni, Rafael Junqueira Borges, Tássia Rafaella Costa, Sante Emmanuel Imai Carone, Marcos Roberto de Mattos Fontes, Suely Vilela Sampaio, Eliane Candiani Arantes, Jan Tytgat
肿瘤
发表日期：2020
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