日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Tirzepatide reduces alcohol drinking and relapse-like behaviours in rodents

替拉帕肽可减少啮齿动物的饮酒量和复发样行为

Edvardsson, Christian E; Adermark, Louise; Gottlieb, Sam; Alfreji, Safana; Emous, Thaynnam A; Gouda, Yomna; Thorsell, Annika; Vujičić, Milica; Aranäs, Cajsa; Benrick, Anna; Wernstedt Asterholm, Ingrid; Lopez, Marcelo F; Becker, Howard C; Jerlhag, Elisabet

Mediodorsal thalamus of alcohol-dependent mice shows genetic and physiological adaptations and alcohol-biased calcium signaling

酒精依赖小鼠的丘脑背内侧核表现出遗传和生理适应性以及酒精偏向性钙信号传导

Martin, Jayden C; Reeves, Kaitlin C; Carter, Kathryn A; Davis, Matthew; Schneider, Amelia; Meade, Elizabeth; Lebonville, Christina L; Nimitvilai-Roberts, Sudarat; Hoffman, Michaela; Woodward, John J; Loewinger, Gabriel; Smith, Rachel J; Lopez, Marcelo F; Becker, Howard C; Mulholland, Patrick J; Rinker, Jennifer A

G9a inhibition reduces stress-potentiated alcohol drinking in both male and female mice: Implications for safe and effective pharmacological therapeutics for alcohol use disorder

G9a抑制剂可降低雄性和雌性小鼠应激增强的饮酒行为:对安全有效的酒精使用障碍药物治疗的启示

Holmes, Deltrice; Lopez, Marcelo F; Becker, Howard C; Cowan, Christopher W; Anderson, Ethan M

Translating medication effects for alcohol use disorder across preclinical, human laboratory, and clinical trial outcomes using meta-analysis

利用荟萃分析方法,将药物对酒精使用障碍的疗效从临床前研究、人体实验室研究和临床试验结果中进行转化

Nieto, Steven J; Donato, Suzanna; Du, Han; Meredith, Lindsay R; Baskerville, Wave-Ananda; McManus, Kaitlin R; Magill, Molly; Lopez, Marcelo F; Becker, Howard C; Ray, Lara A

Effects of chronic ethanol exposure on dorsal medial striatal neurons receiving convergent inputs from the orbitofrontal cortex and basolateral amygdala

慢性乙醇暴露对接受来自眶额皮质和基底外侧杏仁核汇聚输入的背内侧纹状体神经元的影响

Nimitvilai-Roberts, Sudarat; Lopez, Marcelo F; Woodward, John J

Targeting G9a decreases escalated alcohol drinking in male mice in a model of combined stress and chronic alcohol exposure

在同时受到应激和慢性酒精暴露的小鼠模型中,靶向 G9a 可降低雄性小鼠的饮酒量。

Lopez, Marcelo F; Misztak, Paulina; Becker, Howard C; Cowan, Christopher W; Anderson, Ethan M

Cyp2e1 deletion in mice increases sensitivity to ethanol-induced motor impairment and escalation of drinking behavior in the chronic intermittent ethanol model

小鼠Cyp2e1基因缺失会增加慢性间歇性乙醇模型中小鼠对乙醇诱导的运动障碍的敏感性,并加剧饮酒行为。

Gonzalez, Hyland C; Misare, Kelly R; Glorioso, Kate E; Delaney, Joe R; Becker, Howard C; Lopez, Marcelo F; Mulholland, Patrick J; Hartman, Jessica H

Adaptations in glutathione-based redox protein signaling pathways and alcohol drinking across species

不同物种中基于谷胱甘肽的氧化还原蛋白信号通路和饮酒行为的适应性

Womersley, Jacqueline S; Obellianne, Clémence; Padula, Audrey E; Lopez, Marcelo F; Griffin, William C; Ball, Lauren E; Berto, Stefano; Grant, Kathleen A; Townsend, Danyelle M; Uys, Joachim D; Mulholland, Patrick J

Preclinical and clinical evidence for suppression of alcohol intake by apremilast

阿普米司特抑制酒精摄入的临床前和临床证据

Grigsby, Kolter B; Mangieri, Regina A; Roberts, Amanda J; Lopez, Marcelo F; Firsick, Evan J; Townsley, Kayla G; Beneze, Alan; Bess, Jessica; Eisenstein, Toby K; Meissler, Joseph J; Light, John M; Miller, Jenny; Quello, Susan; Shadan, Farhad; Skinner, Michael; Aziz, Heather C; Metten, Pamela; Morrisett, Richard A; Crabbe, John C; Roberto, Marisa; Becker, Howard C; Mason, Barbara J; Ozburn, Angela R

Alcohol Dependence Modifies Brain Networks Activated During Withdrawal and Reaccess: A c-Fos-Based Analysis in Mice.

酒精依赖会改变戒断和再摄入期间激活的大脑网络:基于 c-Fos 的小鼠分析

Roland Alison V, Coelho Cesar A O, Haun Harold L, Gianessi Carol A, Lopez Marcelo F, D'Ambrosio Shannon, Machinski Samantha N, Kroenke Christopher D, Frankland Paul W, Becker Howard C, Kash Thomas L