日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Evaluation of exploratory fluid biomarkers from a phase 1 senolytic trial in mild Alzheimer's disease.

对轻度阿尔茨海默病 1 期衰老细胞清除试验中探索性体液生物标志物的评估

期刊:Neurotherapeutics
影响因子:6.9
doi:10.1016/j.neurot.2025.e00591
Garbarino Valentina R, Palavicini Juan Pablo, Melendez Justin, Barthelemy Nicolas R, He Yingxin, Kautz Tiffany F, Lopez-Cruzan Marisa, Mathews Julia J, Xu Peng, Zhang Bin, Saliba Afaf, Ragi Nagarjunachary, Sharma Kumar, Mason Dallin, Johnson Samuel, Hendrix Suzanne, Craft Suzanne, Petersen Ronald C, Espindola-Netto Jair Machado, Xue Ailing, Tchkonia Tamara, Kirkland James L, Salardini Arash, Musi Nicolas, Bateman Randall J, Gonzales Mitzi M, Orr Miranda E
细胞生物学
细胞衰老
发表日期：2025
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Correction to: Lifespan effects in male UM‑HET3 mice treated with sodium thiosulfate, 16‑hydroxyestriol, and late‑start canagliflozin

更正：用硫代硫酸钠、16-羟基雌三醇和延迟起始卡格列净治疗的雄性UM-HET3小鼠的寿命效应

期刊:Geroscience
影响因子:5.4
doi:10.1007/s11357-024-01283-0
Miller, Richard A; Harrison, David E; Cortopassi, Gino A; Dehghan, Ishmael; Fernandez, Elizabeth; Garratt, Michael; Geisler, John G; Ginsburg, Brett C; Han, Melissa L; Jiang, Nisi; Kaczorowski, Catherine C; Kumar, Navasuja; Leiser, Scott F; Lopez-Cruzan, Marisa; Milne, Ginger; Mitchell, James R; Nelson, James F; Reifsnyder, Peter C; Salmon, Adam B; Xu, Ziying; Korstanje, Ron; Rosenthal, Nadia; Strong, Randy
发表日期：2025
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Correction to: Lifespan effects in male UM‑HET3 mice treated with sodium thiosulfate, 16-hydroxyestradiol, and late‑start canagliflozin

更正：用硫代硫酸钠、16-羟基雌二醇和延迟起始卡格列净治疗的雄性UM-HET3小鼠的寿命效应

期刊:Geroscience
影响因子:5.4
doi:10.1007/s11357-025-01752-0
Miller, Richard A; Harrison, David E; Cortopassi, Gino A; Dehghan, Ishmael; Fernandez, Elizabeth; Garratt, Michael; Geisler, John G; Ginsburg, Brett C; Han, Melissa L; Kaczorowski, Catherine C; Kumar, Navasuja; Leiser, Scott F; Lopez-Cruzan, Marisa; Milne, Ginger; Mitchell, James R; Nelson, James F; Reifsnyder, Peter C; Salmon, Adam B; Korstanje, Ron; Rosenthal, Nadia; Strong, Randy
发表日期：2025
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A Phase IIa clinical trial to evaluate the effects of anti-retroviral therapy in Alzheimer's disease (ART-AD)

一项评估抗逆转录病毒疗法对阿尔茨海默病疗效的 IIa 期临床试验 (ART-AD)

期刊:
影响因子:
doi:10.1038/s44400-024-00001-z
Sullivan, A Campbell; Zuniga, Gabrielle; Ramirez, Paulino; Fernandez, Roman; Wang, Chen-Pin; Li, Ji; Davila, Lisa; Pelton, Kristine; Gomez, Sandra; Sohn, Claira; Gonzalez, Elias; Lopez-Cruzan, Marisa; Gonzalez, David A; Parker, Alicia; Zilli, Eduardo; de Erausquin, Gabriel A; Seshadri, Sudha; Espinoza, Sara; Musi, Nicolas; Frost, Bess
微生物学
阿尔茨海默症
发表日期：2025
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Rapamycin treatment for Alzheimer's disease and related dementias: a pilot phase 1 clinical trial

雷帕霉素治疗阿尔茨海默病及相关痴呆症：一项初步的1期临床试验

期刊:
影响因子:
doi:10.1038/s43856-025-00904-9
Gonzales, Mitzi M; Garbarino, Valentina R; Kautz, Tiffany F; Song, Xuemei; Lopez-Cruzan, Marisa; Linehan, Leslie; Van Skike, Candice E; De Erausquin, Gabriel A; Galvan, Veronica; Orr, Miranda E; Musi, Nicolas; He, Yingxin; Bateman, Randall J; Wang, Chen-Pin; Seshadri, Sudha; Kraig, Ellen; Kellogg, Dean Jr
阿尔茨海默症
发表日期：2025
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Lifespan effects in male UM-HET3 mice treated with sodium thiosulfate, 16-hydroxyestriol, and late-start canagliflozin

用硫代硫酸钠、16-羟基雌三醇和延迟起始卡格列净治疗的雄性UM-HET3小鼠的寿命效应

期刊:Geroscience
影响因子:5.4
doi:10.1007/s11357-024-01176-2
Miller, Richard A; Harrison, David E; Cortopassi, Gino A; Dehghan, Ishmael; Fernandez, Elizabeth; Garratt, Michael; Geisler, John G; Ginsburg, Brett C; Han, Melissa L; Kaczorowski, Catherine C; Kumar, Navasuja; Leiser, Scott F; Lopez-Cruzan, Marisa; Milne, Ginger; Mitchell, James R; Nelson, James F; Reifsnyder, Peter C; Salmon, Adam B; Korstanje, Ron; Rosenthal, Nadia; Strong, Randy
发表日期：2024
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Astaxanthin and meclizine extend lifespan in UM-HET3 male mice; fisetin, SG1002 (hydrogen sulfide donor), dimethyl fumarate, mycophenolic acid, and 4-phenylbutyrate do not significantly affect lifespan in either sex at the doses and schedules used

虾青素和美克洛嗪可延长 UM-HET3 雄性小鼠的寿命；在所用剂量和给药方案下，非瑟酮、SG1002（硫化氢供体）、富马酸二甲酯、霉酚酸和 4-苯基丁酸不会显著影响任何性别的寿命

期刊:Geroscience
影响因子:5.3
doi:10.1007/s11357-023-01011-0
David E Harrison #, Randy Strong #, Peter Reifsnyder, Nadia Rosenthal, Ron Korstanje, Elizabeth Fernandez, Kevin Flurkey, Brett C Ginsburg, Meredith D Murrell, Martin A Javors, Marisa Lopez-Cruzan, James F Nelson, Bradley J Willcox, Richard Allsopp, David M Watumull, David G Watumull, Gino Cortopass
发表日期：2024
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Evaluation of Exploratory Fluid Biomarker Results from a Phase 1 Senolytic Trial in Mild Alzheimer's Disease

轻度阿尔茨海默病 1 期 Senolytic 试验的探索性液体生物标志物结果评估

期刊:
影响因子:
doi:10.21203/rs.3.rs-3994894/v1
Valentina R Garbarino, Juan Pablo Palavicini, Justin Melendez, Nicolas Barthelemy, Yingxin He, Tiffany F Kautz, Marisa Lopez-Cruzan, Julia J Mathews, Peng Xu, Bin Zhan, Afaf Saliba, Nagarjunachary Ragi, Kumar Sharma, Suzanne Craft, Ronald C Petersen, Jair Machado Espindola-Netto, Ailing Xue, Tamara
神经
阿尔茨海默症
发表日期：2024
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A pilot study to investigate the safety and feasibility of antiretroviral therapy for Alzheimer's disease (ART-AD)

一项旨在探讨抗逆转录病毒疗法治疗阿尔茨海默病（ART-AD）的安全性和可行性的试点研究

期刊:
影响因子:
doi:10.1101/2024.02.26.24303316
A Campbell Sullivan, Gabrielle Zuniga, Paulino Ramirez, Roman Fernandez, Chen-Pin Wang, Ji Li, Lisa Davila, Kristine Pelton, Sandra Gomez, Claira Sohn, Elias Gonzalez, Marisa Lopez-Cruzan, David A Gonzalez, Alicia Parker, Eduardo Zilli, Gabriel A de Erausquin, Sudha Seshadri, Sara Espinoza, Nicolas
微生物学
神经
阿尔茨海默症
发表日期：2024
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Senolytic therapy in mild Alzheimer's disease: a phase 1 feasibility trial

轻度阿尔茨海默病的抗衰老疗法：第一阶段可行性试验

期刊:Nature Medicine
影响因子:58.7
doi:10.1038/s41591-023-02543-w
Mitzi M Gonzales, Valentina R Garbarino, Tiffany F Kautz, Juan Pablo Palavicini, Marisa Lopez-Cruzan, Shiva Kazempour Dehkordi, Julia J Mathews, Habil Zare, Peng Xu, Bin Zhang, Crystal Franklin, Mohamad Habes, Suzanne Craft, Ronald C Petersen, Tamara Tchkonia, James L Kirkland, Arash Salardini, Sudh
信号转导
神经
阿尔茨海默症
Senescence
发表日期：2023
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