日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Clinical and molecular predictors of very late recurrence in oestrogen receptor-positive breast cancer patients

雌激素受体阳性乳腺癌患者极晚期复发的临床和分子预测因子

期刊:Breast Cancer Research and Treatment
影响因子:3
doi:10.1007/s10549-024-07311-z
Richman, Juliet; Schuster, Gene; Buus, Richard; Lopez-Knowles, Elena; Dowsett, Mitch
肿瘤
肿瘤免疫
信号转导
乳腺癌
免疫/内分泌
发表日期：2024
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Molecular profiling of aromatase inhibitor sensitive and resistant ER+HER2- postmenopausal breast cancers

对芳香化酶抑制剂敏感和耐药的ER+HER2-绝经后乳腺癌进行分子分型

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-023-39613-z
Schuster, Eugene F; Lopez-Knowles, Elena; Alataki, Anastasia; Zabaglo, Lila; Folkerd, Elizabeth; Evans, David; Sidhu, Kally; Cheang, Maggie Chon U; Tovey, Holly; Salto-Tellez, Manuel; Maxwell, Perry; Robertson, John; Smith, Ian; Bliss, Judith M; Dowsett, Mitch
HER2
肿瘤
肿瘤免疫
乳腺癌
发表日期：2023
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Relationship between ER expression by IHC or mRNA with Ki67 response to aromatase inhibition: a POETIC study

ER IHC 或 mRNA 表达与芳香化酶抑制剂诱导的 Ki67 反应之间的关系：一项 POETIC 研究

期刊:Breast Cancer Research
影响因子:5.6
doi:10.1186/s13058-022-01556-6
Lopez-Knowles, Elena; Detre, Simone; Hills, Margaret; Schuster, Eugene F; Cheang, Maggie C U; Tovey, Holly; Kilburn, Lucy S; Bliss, Judith M; Robertson, John; Mallon, Elizabeth; Skene, Anthony; Evans, Abigail; Smith, Ian; Dowsett, Mitch
发表日期：2022
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Inactivating NF1 Mutations Are Enriched in Advanced Breast Cancer and Contribute to Endocrine Therapy Resistance

失活 NF1 突变在晚期乳腺癌中富集并导致内分泌治疗耐药性

期刊:Clinical Cancer Research
影响因子:10
doi:10.1158/1078-0432.CCR-18-4044
Alex Pearson, Paula Proszek, Javier Pascual, Charlotte Fribbens, Monee K Shamsher, Belinda Kingston, Ben O'Leary, Maria T Herrera-Abreu, Rosalind J Cutts, Isaac Garcia-Murillas, Hannah Bye, Brian A Walker, David Gonzalez De Castro, Lina Yuan, Sabri Jamal, Mike Hubank, Elena Lopez-Knowles, Eugene F S
肿瘤
乳腺癌
发表日期：2020
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Molecular characterisation of aromatase inhibitor-resistant advanced breast cancer: the phenotypic effect of ESR1 mutations

芳香化酶抑制剂耐药性晚期乳腺癌的分子特征：ESR1突变的表型效应

期刊:British Journal of Cancer
影响因子:6.8
doi:10.1038/s41416-018-0345-x
Lopez-Knowles, Elena; Pearson, Alex; Schuster, Gene; Gellert, Pascal; Ribas, Ricardo; Yeo, Belinda; Cutts, Ros; Buus, Richard; Garcia-Murillas, Isaac; Haynes, Ben; Martin, Lesley-Ann; Smith, Ian; Turner, Nick; Dowsett, Mitch
肿瘤免疫
肿瘤
乳腺癌
发表日期：2019
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Impact of a Panel of 88 Single Nucleotide Polymorphisms on the Risk of Breast Cancer in High-Risk Women: Results From Two Randomized Tamoxifen Prevention Trials

88个单核苷酸多态性位点对高危女性乳腺癌风险的影响：两项随机他莫昔芬预防试验的结果

期刊:Journal of Clinical Oncology
影响因子:41.9
doi:10.1200/JCO.2016.69.8944
Cuzick, Jack; Brentnall, Adam R; Segal, Corrinne; Byers, Helen; Reuter, Caroline; Detre, Simone; Lopez-Knowles, Elena; Sestak, Ivana; Howell, Anthony; Powles, Trevor J; Newman, William G; Dowsett, Mitchell
肿瘤
肿瘤免疫
乳腺癌
发表日期：2017
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Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170

6q25 乳腺癌风险变异表现出不同的表型关联并调节 ESR1、RMND1 和 CCDC170

期刊:Nature Genetics
影响因子:31.7
doi:10.1038/ng.3521
Alison M Dunning, Kyriaki Michailidou, Karoline B Kuchenbaecker, Deborah Thompson, Juliet D French, Jonathan Beesley, Catherine S Healey, Siddhartha Kar, Karen A Pooley, Elena Lopez-Knowles, Ed Dicks, Daniel Barrowdale, Nicholas A Sinnott-Armstrong, Richard C Sallari, Kristine M Hillman, Susanne Kau
肿瘤
乳腺癌
发表日期：2016
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Analysis of ESR1 mutation in circulating tumor DNA demonstrates evolution during therapy for metastatic breast cancer

对循环肿瘤DNA中ESR1突变的分析表明，在转移性乳腺癌治疗过程中，ESR1突变会发生演变。

期刊:Science Translational Medicine
影响因子:14.6
doi:10.1126/scitranslmed.aac7551
Schiavon, Gaia; Hrebien, Sarah; Garcia-Murillas, Isaac; Cutts, Rosalind J; Pearson, Alex; Tarazona, Noelia; Fenwick, Kerry; Kozarewa, Iwanka; Lopez-Knowles, Elena; Ribas, Ricardo; Nerurkar, Ashutosh; Osin, Peter; Chandarlapaty, Sarat; Martin, Lesley-Ann; Dowsett, Mitch; Smith, Ian E; Turner, Nicholas C
肿瘤
肿瘤免疫
乳腺癌
发表日期：2015
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Prediction of late distant recurrence in patients with oestrogen-receptor-positive breast cancer: a prospective comparison of the breast-cancer index (BCI) assay, 21-gene recurrence score, and IHC4 in the TransATAC study population

预测雌激素受体阳性乳腺癌患者晚期远处复发：TransATAC 研究人群中乳腺癌指数 (BCI) 检测、21 基因复发评分和 IHC4 的前瞻性比较

期刊:Lancet Oncology
影响因子:35.9
doi:10.1016/S1470-2045(13)70387-5
Sgroi, Dennis C; Sestak, Ivana; Cuzick, Jack; Zhang, Yi; Schnabel, Catherine A; Schroeder, Brock; Erlander, Mark G; Dunbier, Anita; Sidhu, Kally; Lopez-Knowles, Elena; Goss, Paul E; Dowsett, Mitch
肿瘤
肿瘤免疫
信号转导
乳腺癌
免疫/内分泌
发表日期：2013
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β-Catenin signaling is a critical event in ErbB2-mediated mammary tumor progression

β-Catenin 信号传导是 ErbB2 介导的乳腺肿瘤进展中的关键事件

期刊:Cancer Research
影响因子:12.5
doi:10.1158/0008-5472.CAN-12-3925
Babette Schade, Robert Lesurf, Virginie Sanguin-Gendreau, Tung Bui, Geneviève Deblois, Sandra A O'Toole, Ewan K A Millar, Sara J Zardawi, Elena Lopez-Knowles, Robert L Sutherland, Vincent Giguère, Michael Kahn, Michael Hallett, William J Muller
信号转导
肿瘤
乳腺癌
WB
Wnt/β-Catenin
发表日期：2013
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