日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Activated protein C drives β-arrestin-2- and c-Src-dependent phosphorylation of Cav1 and modulates Cav1 association with PAR1 and GRK5.

活化蛋白 C 驱动 β-arrestin-2 和 c-Src 依赖的 Cav1 磷酸化，并调节 Cav1 与 PAR1 和 GRK5 的结合。

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2026.111190
Qin Huaping, Orduña-Castillo Lennis B, Molinar-Inglis Olivia, Gonzalez Ramirez Monica L, Lopez-Ramirez Miguel A, Bardeleben Carolyne, Trejo JoAnn
SRC
CAV1
REST
GRK5
磷酸化
发表日期：2026
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The effects of recombinant human activated factor VII and tranexamic acid on traumatic bleeding and mortality in mice

重组人活化因子VII和氨甲环酸对小鼠创伤性出血和死亡率的影响

期刊:Clinical and Experimental Immunology
影响因子:3.8
doi:10.1111/j.1365-2249.2004.02567.x
Garman, R D; Munroe, K; Richards, S M; Chumappumkal Joseph, Bilgimol; De Pablo-Moreno, Juan Andres; Falah, Nicca; Wentzel, Abraham; Lora Cacho, Mia; Frias-Anaya, Eduardo; Lopez-Ramirez, Miguel A; von Drygalski, Annette
发表日期：2026
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The effects of recombinant human activated factor VII and tranexamic acid on traumatic bleeding and mortality in mice

重组人活化因子VII和氨甲环酸对小鼠创伤性出血和死亡率的影响

期刊:Research and Practice in Thrombosis and Haemostasis
影响因子:3.4
doi:10.1016/j.rpth.2026.103436
Chumappumkal Joseph, Bilgimol; De Pablo-Moreno, Juan Andres; Falah, Nicca; Wentzel, Abraham; Lora Cacho, Mia; Frias-Anaya, Eduardo; Lopez-Ramirez, Miguel A; von Drygalski, Annette
发表日期：2026
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Genetic inactivation of the β1 adrenergic receptor prevents cerebral cavernous malformations in zebrafish

β1肾上腺素能受体的基因失活可预防斑马鱼脑海绵状血管畸形。

期刊:Elife
影响因子:6.4
doi:10.7554/eLife.99455
Li, Wenqing; McCurdy, Sara; Lopez-Ramirez, Miguel A; Lee, Ho-Sup; Ginsberg, Mark H
信号转导
神经科学
免疫/内分泌
发表日期：2025
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Activated protein C promotes β-arrestin-2- and c-Src-dependent caveolin-1 (Cav1) phosphorylation and alters Cav1 association with PAR1 and GRK5

活化蛋白C促进β-arrestin-2和c-Src依赖的caveolin-1 (Cav1)磷酸化，并改变Cav1与PAR1和GRK5的结合。

期刊:
影响因子:
doi:10.1101/2025.11.02.686166
Qin, Huaping; Orduña-Castillo, Lennis B; Molinar-Inglis, Olivia; Gonzalez Ramirez, Monica L; Lopez-Ramirez, Miguel A; Bardeleben, Carolyne; Trejo, JoAnn
信号转导
磷酸化
GRK5
发表日期：2025
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Persistent Activation of Endothelial Cells is Linked to Thrombosis and Inflammation in Cerebral Cavernous Malformation Disease.

脑海绵状血管畸形疾病中内皮细胞的持续激活与血栓形成和炎症有关

期刊:
影响因子:
doi:10.1101/2025.06.29.662238
Gallego-Gutierrez Helios, Frias-Anaya Eduardo, Bui Cassandra, Zhao Louie, Hsu Emily, Indralingam Hannah S, Körbelin Jakob, Trejo JoAnn, Steinberg Jeffrey, Zemke Nathan R, Lopez-Ramirez Miguel A
细胞生物学
脑炎
炎症
发表日期：2025
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Cerebral Cavernous Malformation: From Mechanism to Therapy

脑海绵状血管畸形：从机制到治疗

期刊:Circulation Research
影响因子:16.2
doi:10.1161/CIRCRESAHA.121.318174
Snellings, Daniel A; Hong, Courtney C; Ren, Aileen A; Lopez-Ramirez, Miguel A; Girard, Romuald; Srinath, Abhinav; Marchuk, Douglas A; Ginsberg, Mark H; Awad, Issam A; Kahn, Mark L
神经科学
发表日期：2021
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Comprehensive transcriptome analysis of cerebral cavernous malformation across multiple species and genotypes

对多种物种和基因型的脑海绵状血管畸形进行全面的转录组分析

期刊:JCI Insight
影响因子:6.1
doi:10.1172/jci.insight.126167
Koskimäki, Janne; Girard, Romuald; Li, Yan; Saadat, Laleh; Zeineddine, Hussein A; Lightle, Rhonda; Moore, Thomas; Lyne, Seán; Avner, Kenneth; Shenkar, Robert; Cao, Ying; Shi, Changbin; Polster, Sean P; Zhang, Dongdong; Carrión-Penagos, Julián; Romanos, Sharbel; Fonseca, Gregory; Lopez-Ramirez, Miguel A; Chapman, Eric M; Popiel, Evelyn; Tang, Alan T; Akers, Amy; Faber, Pieter; Andrade, Jorge; Ginsberg, Mark; Derry, W Brent; Kahn, Mark L; Marchuk, Douglas A; Awad, Issam A
神经科学
发表日期：2019
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Transcriptome clarifies mechanisms of lesion genesis versus progression in models of Ccm3 cerebral cavernous malformations

转录组学阐明了Ccm3脑海绵状血管畸形模型中病变发生与进展的机制

期刊:Acta Neuropathologica Communications
影响因子:5.7
doi:10.1186/s40478-019-0789-0
Koskimäki, Janne; Zhang, Dongdong; Li, Yan; Saadat, Laleh; Moore, Thomas; Lightle, Rhonda; Polster, Sean P; Carrión-Penagos, Julián; Lyne, Seán B; Zeineddine, Hussein A; Shi, Changbin; Shenkar, Robert; Romanos, Sharbel; Avner, Kenneth; Srinath, Abhinav; Shen, Le; Detter, Matthew R; Snellings, Daniel; Cao, Ying; Lopez-Ramirez, Miguel A; Fonseca, Gregory; Tang, Alan T; Faber, Pieter; Andrade, Jorge; Ginsberg, Mark; Kahn, Mark L; Marchuk, Douglas A; Girard, Romuald; Awad, Issam A
神经科学
发表日期：2019
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Isolation and Culture of Adult Zebrafish Brain-derived Neurospheres

成年斑马鱼脑源性神经球的分离与培养

期刊:Jove-Journal of Visualized Experiments
影响因子:1
doi:10.3791/53617
Lopez-Ramirez, Miguel A; Calvo, Charles-Félix; Ristori, Emma; Thomas, Jean-Léon; Nicoli, Stefania
神经科学
发表日期：2016
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