Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models
基于结构的高效WD重复结构域5抑制剂的发现,在临床前动物模型中证实了其疗效和安全性。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2211297120
Teuscher, Kevin B; Chowdhury, Somenath; Meyers, Kenneth M; Tian, Jianhua; Sai, Jiqing; Van Meveren, Mayme; South, Taylor M; Sensintaffar, John L; Rietz, Tyson A; Goswami, Soumita; Wang, Jing; Grieb, Brian C; Lorey, Shelly L; Howard, Gregory C; Liu, Qi; Moore, William J; Stott, Gordon M; Tansey, William P; Lee, Taekyu; Fesik, Stephen W