日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Erythromelalgia caused by the missense mutation p.Arg220Pro in an alternatively spliced exon of SCN9A (NaV1.7)

由 SCN9A (NaV1.7) 的可变剪接外显子中的错义突变 p.Arg220Pro 引起的红斑性肢痛症

Jennifer R Deuis, Smitha Kumble, Angelo Keramidas, Lotten Ragnarsson, Cas Simons, Lynn Pais, Susan M White, Irina Vetter

Novel Scorpion Toxin ω-Buthitoxin-Hf1a Selectively Inhibits Calcium Influx via CaV3.3 and CaV3.2 and Alleviates Allodynia in a Mouse Model of Acute Postsurgical Pain

新型蝎毒素 ω-Buthitoxin-Hf1a 选择性抑制通过 CaV3.3 和 CaV3.2 的钙内流,并缓解小鼠急性术后疼痛模型中的异常性疼痛

Dan Wang, Volker Herzig, Zoltan Dekan, K Johan Rosengren, Colton D Payne, Md Mahadhi Hasan, Jiajie Zhuang, Emmanuel Bourinet, Lotten Ragnarsson, Paul F Alewood, Richard J Lewis

Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function

引起疼痛的荨麻毒素靶向 TMEM233 来调节 NaV1.7 功能

Sina Jami #, Jennifer R Deuis #, Tabea Klasfauseweh #, Xiaoyang Cheng, Sergey Kurdyukov, Felicity Chung, Andrei L Okorokov, Shengnan Li, Jiangtao Zhang, Ben Cristofori-Armstrong, Mathilde R Israel, Robert J Ju, Samuel D Robinson, Peng Zhao, Lotten Ragnarsson, Åsa Andersson, Poanna Tran, Vanessa Sche

The structural conformation of the tachykinin domain drives the anti-tumoural activity of an octopus peptide in melanoma BRAFV600E

速激肽结构域的结构构象驱动章鱼肽在黑色素瘤 BRAFV600E 中的抗肿瘤活性

Javier Moral-Sanz, Manuel A Fernandez-Rojo, Gonzalo Colmenarejo, Sergey Kurdyukov, Andreas Brust, Lotten Ragnarsson, Åsa Andersson, Sabela F Vila, Pablo Cabezas-Sainz, Patrick Wilhelm, Ana Vela-Sebastián, Isabel Fernández-Carrasco, Yanni K Y Chin, Yaiza López-Mancheño, Taylor B Smallwood, Richard J

Diindolylmethane Derivatives: New Selective Blockers for T-Type Calcium Channels

二吲哚甲烷衍生物:T 型钙通道的新型选择性阻滞剂

Dan Wang, Pratik Neupane, Lotten Ragnarsson, Robert J Capon, Richard J Lewis

Characterisation of d-Conotoxin TxVIA as a Mammalian T-Type Calcium Channel Modulator

d-芋螺毒素 TxVIA 作为哺乳动物 T 型钙通道调节剂的表征

Dan Wang, S W A Himaya, Jean Giacomotto, Md Mahadhi Hasan, Fernanda C Cardoso, Lotten Ragnarsson, Richard J Lewis

Structure-Function of the High Affinity Substrate Binding Site (S1) of Human Norepinephrine Transporter

人类去甲肾上腺素转运体高亲和力底物结合位点 (S1) 的结构-功能

Prerna Jha, Lotten Ragnarsson, Richard J Lewis

Structure and allosteric activity of a single-disulfide conopeptide from Conus zonatus at human α3β4 and α7 nicotinic acetylcholine receptors

带状芋螺单二硫键芋螺肽对人类 α3β4 和 α7 烟碱乙酰胆碱受体的结构和变构活性

Madhan Kumar Mohan, Nikita Abraham, Rajesh R P, Benjamin Franklin Jayaseelan, Lotten Ragnarsson, Richard J Lewis, Siddhartha P Sarma

Novel analgesic ω-conotoxins from the vermivorous cone snail Conus moncuri provide new insights into the evolution of conopeptides

来自食虫芋螺 Conus moncuri 的新型镇痛 ω-芋螺毒素为芋螺肽的进化提供了新见解

Silmara R Sousa, Jeffrey R McArthur, Andreas Brust, Rebecca F Bhola, K Johan Rosengren, Lotten Ragnarsson, Sebastien Dutertre, Paul F Alewood, Macdonald J Christie, David J Adams, Irina Vetter, Richard J Lewis

Structural mechanisms for α-conotoxin activity at the human α3β4 nicotinic acetylcholine receptor

α-芋螺毒素对人类 α3β4 烟碱乙酰胆碱受体活性的结构机制

Nikita Abraham, Michael Healy, Lotten Ragnarsson, Andreas Brust, Paul F Alewood, Richard J Lewis