日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

SPARC: a structural pathogenicity algorithm for risk classification of hERG variants

SPARC:一种用于hERG变异风险分类的结构致病性算法

Chatelain, Frank C; de Oliveira, Barbara Ribeiro; Grataloup, Guillaume; Robert, Noé; Alameh, Malak; Thollet, Aurélie; Montnach, Jérôme; Feliciangeli, Sylvain; Rio, Aline; Bibault, Floriane; Bichet, Delphine; Bignucolo, Olivier; Extramiana, Fabrice; Majumder, Rupamanjari; Schott, Jean-Jacques; Probst, Vincent; Denjoy, Isabelle; Lesage, Florian; Loussouarn, Gildas; De Waard, Michel

Predicting hERG repolarization power at 37°C from recordings at room temperature

根据室温下的记录预测 37°C 下的 hERG 复极化能力

Oliveira-Mendes, Barbara B R; Alameh, Malak; Montnach, Jérôme; Ollivier, Béatrice; Gibaud, Solène; Feliciangeli, Sylvain; Lesage, Florian; Charpentier, Flavien; Loussouarn, Gildas; De Waard, Michel; Baró, Isabelle

A need for exhaustive and standardized characterization of ion channels activity. The case of K(V)11.1

需要对离子通道活性进行全面且标准化的表征。以K(V)11.1为例

Alameh, Malak; Oliveira-Mendes, Barbara Ribeiro; Kyndt, Florence; Rivron, Jordan; Denjoy, Isabelle; Lesage, Florian; Schott, Jean-Jacques; De Waard, Michel; Loussouarn, Gildas

Modelling sudden cardiac death risks factors in patients with coronavirus disease of 2019: the hydroxychloroquine and azithromycin case

对2019冠状病毒病患者猝死风险因素进行建模:羟氯喹和阿奇霉素病例

Montnach, Jérôme; Baró, Isabelle; Charpentier, Flavien; De Waard, Michel; Loussouarn, Gildas

A consistent arrhythmogenic trait in Brugada syndrome cellular phenotype

布鲁加达综合征细胞表型中一致的致心律失常特征

Al Sayed, Zeina R; Jouni, Mariam; Gourraud, Jean-Baptiste; Belbachir, Nadjet; Barc, Julien; Girardeau, Aurore; Forest, Virginie; Derevier, Aude; Gaignerie, Anne; Chariau, Caroline; Cimarosti, Bastien; Canac, Robin; Olchesqui, Pierre; Charpentier, Eric; Schott, Jean-Jacques; Redon, Richard; Baró, Isabelle; Probst, Vincent; Charpentier, Flavien; Loussouarn, Gildas; Zibara, Kazem; Lamirault, Guillaume; Lemarchand, Patricia; Gaborit, Nathalie

A standardised hERG phenotyping pipeline to evaluate KCNH2 genetic variant pathogenicity

用于评估 KCNH2 基因变异致病性的标准化 hERG 表型分析流程

Oliveira-Mendes, Barbara; Feliciangeli, Sylvain; Ménard, Mélissa; Chatelain, Frank; Alameh, Malak; Montnach, Jérôme; Nicolas, Sébastien; Ollivier, Béatrice; Barc, Julien; Baró, Isabelle; Schott, Jean-Jacques; Probst, Vincent; Kyndt, Florence; Denjoy, Isabelle; Lesage, Florian; Loussouarn, Gildas; De Waard, Michel

Editorial: Molecular Mechanisms of Voltage-Gating in Ion Channels

社论:离子通道电压门控的分子机制

Loussouarn, Gildas; Tarek, Mounir

Computer modeling of whole-cell voltage-clamp analyses to delineate guidelines for good practice of manual and automated patch-clamp

利用计算机建模进行全细胞电压钳分析,以制定手动和自动膜片钳良好操作规范。

Montnach, Jérôme; Lorenzini, Maxime; Lesage, Adrien; Simon, Isabelle; Nicolas, Sébastien; Moreau, Eléonore; Marionneau, Céline; Baró, Isabelle; De Waard, Michel; Loussouarn, Gildas

Up-regulation of voltage-gated sodium channels by peptides mimicking S4-S5 linkers reveals a variation of the ligand-receptor mechanism.

模拟 S4-S5 连接肽的肽对电压门控钠通道的上调揭示了配体-受体机制的一种变化

Malak Olfat A, Abderemane-Ali Fayal, Wei Yue, Coyan Fabien C, Pontus Gilyane, Shaya David, Marionneau Céline, Loussouarn Gildas

Voltage-dependent activation in EAG channels follows a ligand-receptor rather than a mechanical-lever mechanism

EAG通道的电压依赖性激活遵循配体-受体机制,而非机械杠杆机制。

Malak, Olfat A; Gluhov, Grigory S; Grizel, Anastasia V; Kudryashova, Kseniya S; Sokolova, Olga S; Loussouarn, Gildas