Loutit相关文献与解析，生知库 | 链接生命科学的每一步

Chen Yuh-Tarng, de Thomas Wagner Dominica, Loutit Alastair J, Nourizonoz Ali, Ulanova Marina, Graikou Danai, Chang Man-Shan, Croisier-Coeytaux Mary-Claude, Clerc-Rosset StÃ©phanie, Blanc JÃ©rÃ´me, Knott Graham, Lee Kuo-Sheng, Huber Daniel

细胞生物学

炎性小体

发表日期：2025

文献求助收藏

Phase 1 study of the safety, tolerability, and pharmacokinetics of a synthetic macrocyclic peptide antibiotic (BRII-693) in healthy adult participants

一项针对健康成年受试者的合成大环肽类抗生素（BRII-693）的安全性、耐受性和药代动力学的I期研究

期刊:Antimicrobial Agents and Chemotherapy

影响因子:4.5

doi:10.1128/aac.01288-24

Watkins, Michael; Zhu, Yali; Griffith, David C; Loutit, Jeffery S; Margolis, David; Gu, Peidi

发表日期：2025

文献求助收藏

Phase 1, randomized, double-blind, placebo-controlled, ascending single- and multiple-dose study of the safety, tolerability, and pharmacokinetics of intravenous xeruborbactam (QPX7728) in healthy adult subjects

一项 I 期随机、双盲、安慰剂对照、递增单剂量和多剂量研究，旨在评估静脉注射沙博巴坦 (QPX7728) 在健康成年受试者中的安全性、耐受性和药代动力学。

期刊:Antimicrobial Agents and Chemotherapy

影响因子:4.5

doi:10.1128/aac.00784-25

Hernández-Mitre, María Patricia; Wallis, Steven C; Loutit, Jeffery S; Griffith, David C; Roberts, Jason A

发表日期：2025

文献求助收藏

A phase I, randomized, double-blind, placebo-controlled, ascending single- and multiple-dose study of the pharmacokinetics, safety, and tolerability of oral ceftibuten in healthy adult subjects

一项 I 期随机、双盲、安慰剂对照、递增单剂量和多剂量研究，旨在评估口服头孢布烯在健康成年受试者中的药代动力学、安全性和耐受性。

期刊:Antimicrobial Agents and Chemotherapy

影响因子:4.5

doi:10.1128/aac.01099-23

Hernández-Mitre, María Patricia; Wallis, Steven C; Morgan, Elizabeth E; Dudley, Michael N; Loutit, Jeffery S; Griffith, David C; Roberts, Jason A

发表日期：2024

文献求助收藏

A Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of Biapenem in Healthy Adult Subjects

一项评估比阿培南在健康成年受试者中安全性、耐受性和药代动力学的I期研究

期刊:Antimicrobial Agents and Chemotherapy

影响因子:4.5

doi:10.1128/AAC.02612-20

Griffith, David C; Morgan, Elizabeth E; Dudley, Michael N; Loutit, Jeffery S

发表日期：2023

文献求助收藏

In vitro potency of xeruborbactam in combination with multiple β-lactam antibiotics in comparison with other β-lactam/β-lactamase inhibitor (BLI) combinations against carbapenem-resistant and extended-spectrum β-lactamase-producing Enterobacterales

与其他 β-内酰胺/β-内酰胺酶抑制剂 (BLI) 组合相比，xeruborbactam 与多种 β-内酰胺类抗生素组合对耐卡巴培南和产超广谱 β-内酰胺酶的肠杆菌的体外效力

期刊:Antimicrobial Agents and Chemotherapy

影响因子:4.1

doi:10.1128/aac.00440-23

Olga Lomovskaya, Mariana Castanheira, Jill Lindley, Debora Rubio-Aparicio, Kirk Nelson, Ruslan Tsivkovski, Dongxu Sun, Maxim Totrov, Jeffery Loutit, Michael Dudley

免疫

发表日期：2023

文献求助收藏

Pharmacokinetic-Pharmacodynamic Target Attainment Analyses as Support for Meropenem-Vaborbactam Dosing Regimens and Susceptibility Breakpoints

药代动力学-药效学目标达成分析为美罗培南-伐博巴坦给药方案和敏感性断点提供支持

期刊:Antimicrobial Agents and Chemotherapy

影响因子:4.5

doi:10.1128/aac.02130-21

Bhavnani, S M; Trang, M; Griffith, D C; Lomovskaya, O; Hammel, J P; Loutit, J S; Cammarata, S K; Dudley, M N; Ambrose, P G; Rubino, C M

发表日期：2022

文献求助收藏

The Ultrabroad-Spectrum Beta-Lactamase Inhibitor QPX7728 Restores the Potency of Multiple Oral Beta-Lactam Antibiotics against Beta-Lactamase-Producing Strains of Resistant Enterobacterales

超广谱β-内酰胺酶抑制剂 QPX7728 可恢复多种口服 β-内酰胺抗生素对耐药肠杆菌产生 β-内酰胺酶菌株的效力

期刊:Antimicrobial Agents and Chemotherapy

影响因子:4.1

doi:10.1128/AAC.02168-21

Olga Lomovskaya, Debora Rubio-Aparicio, Ruslan Tsivkovski, Jeff Loutit, Michael Dudley

免疫

发表日期：2022

文献求助收藏

In Vitro Activity of the Ultrabroad-Spectrum Beta-Lactamase Inhibitor QPX7728 in Combination with Multiple Beta-Lactam Antibiotics against Pseudomonas aeruginosa

超广谱β-内酰胺酶抑制剂QPX7728与多种β-内酰胺类抗生素联合使用对铜绿假单胞菌的体外活性

期刊:Antimicrobial Agents and Chemotherapy

影响因子:4.5

doi:10.1128/AAC.00210-21

Lomovskaya, Olga; Rubio-Aparicio, Debora; Nelson, Kirk; Sun, Dongxu; Tsivkovski, Ruslan; Castanheira, Mariana; Lindley, Jill; Loutit, Jeffery; Dudley, Michael

发表日期：2021

文献求助收藏

The role of skin mechanics in contact force variation under different friction conditions

皮肤力学在不同摩擦条件下接触力变化中的作用

Lamellar Schwann cells in the Pacinian corpuscle potentiate vibration perception.

帕西尼小体中的层状雪旺细胞增强振动感知

Phase 1 study of the safety, tolerability, and pharmacokinetics of a synthetic macrocyclic peptide antibiotic (BRII-693) in healthy adult participants

一项针对健康成年受试者的合成大环肽类抗生素（BRII-693）的安全性、耐受性和药代动力学的I期研究

Phase 1, randomized, double-blind, placebo-controlled, ascending single- and multiple-dose study of the safety, tolerability, and pharmacokinetics of intravenous xeruborbactam (QPX7728) in healthy adult subjects

一项 I 期随机、双盲、安慰剂对照、递增单剂量和多剂量研究，旨在评估静脉注射沙博巴坦 (QPX7728) 在健康成年受试者中的安全性、耐受性和药代动力学。

A phase I, randomized, double-blind, placebo-controlled, ascending single- and multiple-dose study of the pharmacokinetics, safety, and tolerability of oral ceftibuten in healthy adult subjects

一项 I 期随机、双盲、安慰剂对照、递增单剂量和多剂量研究，旨在评估口服头孢布烯在健康成年受试者中的药代动力学、安全性和耐受性。

A Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of Biapenem in Healthy Adult Subjects

一项评估比阿培南在健康成年受试者中安全性、耐受性和药代动力学的I期研究

In vitro potency of xeruborbactam in combination with multiple β-lactam antibiotics in comparison with other β-lactam/β-lactamase inhibitor (BLI) combinations against carbapenem-resistant and extended-spectrum β-lactamase-producing Enterobacterales

与其他 β-内酰胺/β-内酰胺酶抑制剂 (BLI) 组合相比，xeruborbactam 与多种 β-内酰胺类抗生素组合对耐卡巴培南和产超广谱 β-内酰胺酶的肠杆菌的体外效力

Pharmacokinetic-Pharmacodynamic Target Attainment Analyses as Support for Meropenem-Vaborbactam Dosing Regimens and Susceptibility Breakpoints

药代动力学-药效学目标达成分析为美罗培南-伐博巴坦给药方案和敏感性断点提供支持

The Ultrabroad-Spectrum Beta-Lactamase Inhibitor QPX7728 Restores the Potency of Multiple Oral Beta-Lactam Antibiotics against Beta-Lactamase-Producing Strains of Resistant Enterobacterales

超广谱β-内酰胺酶抑制剂 QPX7728 可恢复多种口服 β-内酰胺抗生素对耐药肠杆菌产生 β-内酰胺酶菌株的效力

In Vitro Activity of the Ultrabroad-Spectrum Beta-Lactamase Inhibitor QPX7728 in Combination with Multiple Beta-Lactam Antibiotics against Pseudomonas aeruginosa

超广谱β-内酰胺酶抑制剂QPX7728与多种β-内酰胺类抗生素联合使用对铜绿假单胞菌的体外活性