日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pichia-CLM: A language model-based codon optimization pipeline for Komagataella phaffii.

Pichia-CLM:一种基于语言模型的毕赤酵母密码子优化流程。

Narayanan Harini, Love J Christopher

Systematic perturbation of cultures of K. phaffii by carbon co-feeding show gene signatures associated with production of recombinant proteins

通过碳源共添加对克鲁维酵母培养物进行系统性扰动,可观察到与重组蛋白产生相关的基因特征。

Acharya, Raghav; Hinckley, Joshua; Barry, Rachel; Cha, Eugenie; Narayanan, Harini; Sunday, Brittney C; Ford, Hayley; Whittaker, Charles A; Love, J Christopher

Molecular determinants of antibody-mediated priming to enhance detection of ctDNA

抗体介导的启动作用增强ctDNA检测的分子决定因素

Tabrizi, Shervin; Sullivan, Claire; Chakraborty, Kasturi; Martin-Alonso, Carmen; An, Zhenyi; Gao, Lily; Kim, Daniel M; Patel, Savan K; Blewett, Timothy; Rhoades, Justin; Liu, Ruolin; Patel, Sahil; Xiong, Kan; Crnjac, Andjela; Bhatia, Sangeeta N; Adalsteinsson, Viktor A; Love, J Christopher

Lymph node resident memory T cells retain effector capabilities by evading lung resident memory dysfunction.

淋巴结驻留记忆 T 细胞通过逃避肺部驻留记忆功能障碍来保留效应能力。

Heim Taylor A, Rogers Zachary J, Duquette Sarah, Carney Molly Y, Bhandarkar Vidit, Chatterjee Fiona, Bhandarkar Teresa, Schenkel Jason M, Manalis Scott, Love J Christopher, Spranger Stefani

Modulating cell-free DNA biology as the next frontier in liquid biopsies

调控无细胞DNA生物学是液体活检的下一个前沿领域

Tabrizi, Shervin; Martin-Alonso, Carmen; Xiong, Kan; Bhatia, Sangeeta N; Adalsteinsson, Viktor A; Love, J Christopher

Adaptation of Aglycosylated Monoclonal Antibodies for Improved Production in Komagataella phaffii

利用非糖基化单克隆抗体提高柯马加塔氏菌(Komagataella phaffii)的产量

Yang, Yuchen; Dalvie, Neil C; Brady, Joseph R; Naranjo, Christopher A; Lorgeree, Timothy; Rodriguez-Aponte, Sergio A; Johnston, Ryan S; Tracey, Mary K; Elenberger, Carmen M; Lee, Eric; Tié, Mark; Love, Kerry R; Love, J Christopher

GPR15 and CD38 define a subset of peripheral blood pathogenic effector Th2 cells associated with active eosinophilic esophagitis

GPR15 和 CD38 定义了一类与活动性嗜酸性食管炎相关的外周血致病性效应 Th2 细胞亚群。

Burk, Caitlin M; Morgan, Duncan M; Glickman, Jonathan N; Virkud, Yamini V; Liao, Emily; Moseley, Elizabeth G; Canziani, Karina; Bhowmik, Moumita; Li, Jennifer C; Keswani, Tarun; Virk-Hundal, Navneet K; Katz, Aubrey J; Yuan, Qian; Patil, Sarita U; Love, J Christopher; Shreffler, Wayne G

PD-1 blockade during T cell priming enhances long-term protection against metastatic tumors by epigenetically tuning T cell exhaustion

在T细胞启动过程中阻断PD-1可通过表观遗传调控T细胞耗竭,增强对转移性肿瘤的长期保护作用。

Dinter, Teresa; Mackowiak, Sebastian; Rogers, Zachary J; Bhandarkar, Vidit; Carney, Molly Y; Zhang, Yiming J; Morgan, Duncan; Pop, Lorelai; Chatterjee, Fiona; Lutz, Emi; Jain, Yajit; Radhakrishnan, Adityanarayanan; Lander, Eric; Dane Wittrup, K; Love, J Christopher; Meissner, Alexander; Spranger, Stefani

Expansion of tumor-reactive CD8(+) T cell clonotypes occurs in the spleen in response to immune checkpoint blockade

免疫检查点阻断后,脾脏中肿瘤反应性CD8(+) T细胞克隆型会发生扩增。

Morgan, Duncan M; Horton, Brendan L; Bhandarkar, Vidit; Van, Richard; Dinter, Teresa; Zagorulya, Maria; Love, J Christopher; Spranger, Stefani

CRISPR-Cas9 knockout screen informs efficient reduction of the Komagataella phaffii secretome

CRISPR-Cas9基因敲除筛选揭示了有效减少Komagataella phaffii分泌组的方法

Dalvie, Neil C; Lorgeree, Timothy R; Yang, Yuchen; Rodriguez-Aponte, Sergio A; Whittaker, Charles A; Hinckley, Joshua A; Clark, John J; Del Rosario, Amanda M; Love, Kerry R; Love, J Christopher