日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structure-Guided Semisynthesis of Blasticidin S-Amicetin Chimeras as Selective Ribosome Inhibitors

以结构为导向的杀稻瘟菌素S-阿米西汀嵌合体半合成作为选择性核糖体抑制剂

Gannett, Cole; Tiller, Kateland; Abdelmegeed, Somaia; Hoernig, Micah; Abouelkhair, Ahmed A; Seleem, Mohamed N; Weger-Lucarelli, James; Brown, Anne M; Lowell, Andrew N

Natural and Synthetic LDL-Based Imaging Probes for the Detection of Atherosclerotic Plaques.

用于检测动脉粥样硬化斑块的天然和合成 LDL 基成像探针

Fracassi Alessandro, Qiao Hui, Lowell Andrew N, Cao Jianbo, Bode Jeffrey W, Masai Hisao, Yoshizawa-Sugata Naoko, Zhou Rong, Yamakoshi Yoko

Highly Active Oligoethylene Glycol Pleuromutilins via Systematic Linker Synthesis/One-Pot Attachment and a Microscale Solubility Method

通过系统连接子合成/一锅法连接和微尺度溶解度法制备高活性低聚乙二醇侧耳素

Breiner, Logan M; Slowinski, Roman P; Lowell, Andrew N

Annulation Methods toward the Total Synthesis of Thermorubin: Construction of the AB and BCD Ring Systems

环化方法在热红素全合成中的应用:AB和BCD环系的构建

Kohanov, Zachary A; Lowell, Andrew N

Forgotten Natural Products: Semisynthetic Development of Blasticidin S As an Antibiotic Lead

被遗忘的天然产物:半合成开发杀稻瘟菌素S作为抗生素先导化合物

Gannett, Cole; Tiller, Kateland; Briganti, Anthony J; Brown, Anne M; Weger-Lucarelli, James; Lowell, Andrew N

Computationally-guided exchange of substrate selectivity motifs in a modular polyketide synthase acyltransferase

模块化聚酮合酶酰基转移酶中底物选择性基序的计算引导交换

Kalkreuter, Edward; Bingham, Kyle S; Keeler, Aaron M; Lowell, Andrew N; Schmidt, Jennifer J; Sherman, David H; Williams, Gavin J

Ribosome-binding and anti-microbial studies of the mycinamicins, 16-membered macrolide antibiotics from Micromonospora griseorubida.

对来自灰红小单孢菌的 16 元大环内酯类抗生素——霉素的核糖体结合和抗菌研究

Breiner-Goldstein Elinor, Eyal Zohar, Matzov Donna, Halfon Yehuda, Cimicata Giuseppe, Baum Moti, Rokney Assaf, Ezernitchi Analia V, Lowell Andrew N, Schmidt Jennifer J, Rozenberg Haim, Zimmerman Ella, Bashan Anat, Valinsky Lea, Anzai Yojiro, Sherman David H, Yonath Ada

Control of Stereoselectivity in Diverse Hapalindole Metabolites is Mediated by Cofactor-Induced Combinatorial Pairing of Stig Cyclases

多种哈帕林吲哚代谢物的立体选择性控制是由辅因子诱导的斯蒂格环化酶组合配对介导的

Li, Shasha; Newmister, Sean A; Lowell, Andrew N; Zi, Jiachen; Chappell, Callie R; Yu, Fengan; Hohlman, Robert M; Orjala, Jimmy; Williams, Robert M; Sherman, David H

Probing Selectivity and Creating Structural Diversity Through Hybrid Polyketide Synthases

通过杂合聚酮合酶探索选择性并创造结构多样性

Koch, Aaron A; Schmidt, Jennifer J; Lowell, Andrew N; Hansen, Douglas A; Coburn, Katherine M; Chemler, Joseph A; Sherman, David H

Multicomponent Microscale Biosynthesis of Unnatural Cyanobacterial Indole Alkaloids

非天然蓝藻吲哚生物碱的多组分微尺度生物合成

Khatri, Yogan; Hohlman, Robert M; Mendoza, Johnny; Li, Shasha; Lowell, Andrew N; Asahara, Haruichi; Sherman, David H