日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Exploring experiences of the regulatory toxicology system: system-level promoters and inhibitors of new approach methodologies

探索监管毒理学体系的经验:新方法论的系统级促进因素和抑制因素

Bearth, Angela; Kopainsky, Birgit; Jones, Lowenna B; Vist, Gunn E; Husøy, Trine; Svendsen, Camilla; Whaley, Paul; Hoffmann, Sebastian; Ames, Heather M; Solstad, Gisle; Bloch, Denise; Čavoški, Aleksandra; Chiu, Weihsueh A; Davenport, Miles; Davies, Holly G; Giusti, Arianna; Hartung, Thomas; Kwon, Seok; Osborne, Olivia J; Rooney, Andrew A; Rousselle, Christophe; Sass, Jennifer B; Wright, Fred A; Mathisen, Gro H

Time for CHANGE: system-level interventions for bringing forward the date of effective use of NAMs in regulatory toxicology

变革的时刻到了:通过系统层面的干预措施,加快在监管毒理学中有效使用新型合成代谢物(NAMs)的步伐。

Mathisen, Gro H; Bearth, Angela; Jones, Lowenna B; Hoffmann, Sebastian; Vist, Gunn E; Ames, Heather M; Husøy, Trine; Svendsen, Camilla; Tsaioun, Katya; Ashikaga, Takao; Bloch, Denise; Cavoski, Aleksandra; Chiu, Weihsueh A; Davies, Holly G; Giusti, Arianna; Hartung, Thomas; Hirabayashi, Yoko; Hogberg, Helena T; Joglekar, Rashmi; Kojima, Hajime; Krishnan, Kannan; Kwon, Seok; Osborne, Olivia J; Roggen, Erwin; Rooney, Andrew A; Rousselle, Christophe; Sass, Jennifer B; Sepai, Ovnair; Simanainen, Ulla; Thayer, Kristina A; Tong, Weida; Wikoff, Daniele; Wright, Fred; Whaley, Paul

Grb7, Grb10 and Grb14, encoding the growth factor receptor-bound 7 family of signalling adaptor proteins have overlapping functions in the regulation of fetal growth and post-natal glucose metabolism

Grb7、Grb10 和 Grb14 编码生长因子受体结合蛋白 7 家族的信号转导衔接蛋白,它们在调节胎儿生长和出生后葡萄糖代谢方面具有重叠的功能。

Moorwood, Kim; Smith, Florentia M; Garfield, Alastair S; Cowley, Michael; Holt, Lowenna J; Daly, Roger J; Ward, Andrew

How do tumours outside the gastrointestinal tract respond to dietary fibre supplementation?

胃肠道外的肿瘤对膳食纤维补充剂有何反应?

Asim, Fatima; Clarke, Lowenna; Donnelly, Elizabeth; Jamal, Fouzia Rahana; Piccicacchi, Lucrezia Maria; Qadir, Mahanoor; Raja, Nain Tara; Samadi, Cyrus; Then, Chee Kin; Kiltie, Anne E

Childhood stress impairs social function through AVP-dependent mechanisms

童年压力通过AVP依赖性机制损害社会功能。

Brydges, Nichola M; Hall, Jessica; Best, Caroline; Rule, Lowenna; Watkin, Holly; Drake, Amanda J; Lewis, Catrin; Thomas, Kerrie L; Hall, Jeremy

Sex specific effects of pre-pubertal stress on hippocampal neurogenesis and behaviour

青春期前压力对海马神经发生和行为的性别特异性影响

Nichola Marie Brydges, Anna Moon, Lowenna Rule, Holly Watkin, Kerrie L Thomas, Jeremy Hall

Ablation of Grb10 Specifically in Muscle Impacts Muscle Size and Glucose Metabolism in Mice

肌肉中 Grb10 的消融对小鼠的肌肉大小和葡萄糖代谢有影响

Lowenna J Holt, Amanda E Brandon, Lewin Small, Eurwin Suryana, Elaine Preston, Donna Wilks, Nancy Mokbel, Chantal A Coles, Jason D White, Nigel Turner, Roger J Daly, Gregory J Cooney

Molecular determinants of Grb14-mediated inhibition of insulin signaling

Grb14 介导的胰岛素信号抑制的分子决定因素

Diana Goenaga, Cornelia Hampe, Nadège Carré, Katia Cailliau, Edith Browaeys-Poly, Dominique Perdereau, Lowenna J Holt, Roger J Daly, Jean Girard, Isabelle Broutin, Tarik Issad, Anne-Françoise Burnol

Mice with a disruption of the imprinted Grb10 gene exhibit altered body composition, glucose homeostasis, and insulin signaling during postnatal life

Grb10 印迹基因缺失的小鼠在出生后表现出身体成分、葡萄糖稳态和胰岛素信号传导的改变。

Smith, Florentia M; Holt, Lowenna J; Garfield, Alastair S; Charalambous, Marika; Koumanov, Francoise; Perry, Mark; Bazzani, Reto; Sheardown, Steven A; Hegarty, Bronwyn D; Lyons, Ruth J; Cooney, Gregory J; Daly, Roger J; Ward, Andrew

Grb10 and Grb14: enigmatic regulators of insulin action--and more?

Grb10 和 Grb14:胰岛素作用的神秘调节因子——还有更多作用?

Holt, Lowenna J; Siddle, Kenneth