日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Constructing the cure: engineering the next wave of antibody and cellular immune therapies

构建治愈方案:设计下一代抗体和细胞免疫疗法

Bailey, Stefanie R; Bartee, Eric; Daniels, Kyle G; Heery, Christopher R; Kaumaya, Pravin; Lesinski, Gregory B; Lowinger, Timothy B; Nelson, Michelle H; Rubinstein, Mark P; Wittling, Megen C; Paulos, Chrystal M; Posey, Avery D Jr

XMT-2056, a HER2-Directed STING Agonist Antibody-Drug Conjugate, Induces Innate Antitumor Immune Responses by Acting on Cancer Cells and Tumor-Resident Immune Cells.

XMT-2056 是一种 HER2 靶向 STING 激动剂抗体药物偶联物,通过作用于癌细胞和肿瘤驻留免疫细胞来诱导先天性抗肿瘤免疫反应

Bukhalid Raghida A, Duvall Jeremy R, Lancaster Kelly, Catcott Kalli C, Malli Cetinbas Naniye, Monnell Travis, Routhier Caitlin, Thomas Joshua D, Bentley Keith W, Collins Scott D, Ditty Elizabeth, Eitas Timothy K, Kelleher Eugene W, Shaw Pamela, Soomer-James Jahna, Ter-Ovanesyan Elena, Xu Ling, Zurita Jeffrey, Toader Dorin, Damelin Marc, Lowinger Timothy B

PBPK Modeling to Predict Clinical Drug-Drug Interaction and Impact of Hepatic Impairment for an ADC With the Payload Auristatin F-Hydroxypropylamide

利用生理药代动力学模型预测载药抗体偶联药物(ADC)药物奥瑞他汀F-羟丙基酰胺的临床药物相互作用及肝功能损害的影响

Kumar, Niyanta; Dixit, Vaishali; Burt, Howard; Gill, Katherine L; Jones, Hannah M; Keirstead, Natalie; Su, Dian; Toader, Dorin; Lowinger, Timothy B