日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Stability Oracle: a structure-based graph-transformer framework for identifying stabilizing mutations

稳定性预言机:一种基于结构的图变换框架,用于识别稳定突变

Diaz, Daniel J; Gong, Chengyue; Ouyang-Zhang, Jeffrey; Loy, James M; Wells, Jordan; Yang, David; Ellington, Andrew D; Dimakis, Alexandros G; Klivans, Adam R

Grain engineering for efficient near-infrared perovskite light-emitting diodes

晶粒工程助力高效近红外钙钛矿发光二极管

Baek, Sung-Doo; Shao, Wenhao; Feng, Weijie; Tang, Yuanhao; Lee, Yoon Ho; Loy, James; Gunnarsson, William B; Yang, Hanjun; Zhang, Yuchen; Faheem, M Bilal; Kaswekar, Poojan Indrajeet; Atapattu, Harindi R; Qin, Jiajun; Coffey, Aidan H; Park, Jee Yung; Yang, Seok Joo; Yang, Yu-Ting; Zhu, Chenhui; Wang, Kang; Graham, Kenneth R; Gao, Feng; Qiao, Quinn; Guo, L Jay; Rand, Barry P; Dou, Letian

Application of Pharmacokinetic/Pharmacodynamic Modeling to Bridge Mouse Antitumor Efficacy and Monkey Toxicology Data for Determining the Therapeutic Index of an Interleukin-10 Fc Fusion Protein.

应用药代动力学/药效学模型连接小鼠抗肿瘤疗效和猴子毒理学数据,以确定白细胞介素-10 Fc融合蛋白的治疗指数

Yang Zheng, Loy James, Poirson Brian, Dai Yanshan, Rajendran Surendran, Xu Shihua, Spires Vanessa, Gururajan Murali, Lin Zheng, Arbanas Jaren, Carl Stephen, Pace Samantha, Wang Yun, Mehl John, Vasudevan Krishna, Spires Thomas, Novosiadly Ruslan, Coker Shodeinde, Perez Raymond, Covello Kelly, Morin Paul, Graziano Robert, Broz Miranda, Lehman-McKeeman Lois

Acute Neurotoxicity of Antisense Oligonucleotides After Intracerebroventricular Injection Into Mouse Brain Can Be Predicted from Sequence Features

反义寡核苷酸脑室内注射入小鼠脑后产生的急性神经毒性可根据序列特征进行预测。

Hagedorn, Peter H; Brown, Jeffrey M; Easton, Amy; Pierdomenico, Maria; Jones, Kelli; Olson, Richard E; Mercer, Stephen E; Li, Dong; Loy, James; Høg, Anja M; Jensen, Marianne L; Gill, Martin; Cacace, Angela M

Learning the local landscape of protein structures with convolutional neural networks

利用卷积神经网络学习蛋白质结构的局部景观

Kulikova, Anastasiya V; Diaz, Daniel J; Loy, James M; Ellington, Andrew D; Wilke, Claus O

Safety and efficacy of anti-PD-L1 therapy in the woodchuck model of HBV infection

抗PD-L1疗法在土拨鼠HBV感染模型中的安全性和有效性

Balsitis, Scott; Gali, Volodymyr; Mason, Pamela J; Chaniewski, Susan; Levine, Steven M; Wichroski, Michael J; Feulner, Michael; Song, Yunling; Granaldi, Karen; Loy, James K; Thompson, Chris M; Lesniak, Jacob A; Brockus, Catherine; Kishnani, Narendra; Menne, Stephan; Cockett, Mark I; Iyer, Renuka; Mason, Stephen W; Tenney, Daniel J

Large genomic differences between Moraxella bovoculi isolates acquired from the eyes of cattle with infectious bovine keratoconjunctivitis versus the deep nasopharynx of asymptomatic cattle

从患有传染性牛角结膜炎的牛眼中分离出的牛莫拉菌与从无症状牛鼻咽深处分离出的牛莫拉菌之间存在很大基因组差异

Aaron M Dickey, John D Loy, James L Bono, Timothy P L Smith, Mike D Apley, Brian V Lubbers, Keith D DeDonder, Sarah F Capik, Robert L Larson, Brad J White, Jochen Blom, Carol G Chitko-McKown, Michael L Clawson3