日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Safety, tolerability, and efficacy of the PD-1 agonist antibody JNJ-67484703 in adults with active rheumatoid arthritis: results of a multicenter, double-blind, placebo-controlled, randomized, multiple-dose phase Ib study

PD-1激动剂抗体JNJ-67484703在活动性类风湿关节炎成人患者中的安全性、耐受性和有效性:一项多中心、双盲、安慰剂对照、随机、多剂量Ib期研究的结果

Ling, Irving T C; Marciniak, Stanley J; Clarke, Stephen H; Lakshminarayanan, Vani; Loza, Matthew J; Liva, Sophia G; Wang, Tong; Orillion, Ashley; Tikhonov, Ilia; Noss, Erika H

Nipocalimab, an anti-FcRn monoclonal antibody, in participants with moderate to severe active rheumatoid arthritis and inadequate response or intolerance to anti-TNF therapy: results from the phase 2a IRIS-RA study

尼波卡利单抗(一种抗FcRn单克隆抗体)用于治疗对TNF抑制剂治疗反应不足或不耐受的中重度活动性类风湿关节炎患者:来自2a期IRIS-RA研究的结果

Taylor, Peter C; Schett, Georg; Huizinga, Tom Wj; Wang, Qingmin; Ibrahim, Fowzia; Zhou, Bei; Liva, Sophia G; Shaik, Jafar Sadik B; Xiong, Yuan; Leu, Jocelyn H; Panchakshari, Rohit A; Loza, Matthew J; Ma, Keying; Dhatt, Harman; Rojo Cella, Ricardo; Karyekar, Chetan S; Cuff, Carolyn A; Gao, Sheng; Fei, Kaiyin

Using an electronic diary and wristband accelerometer to detect exacerbations and activity levels in COPD: a feasibility study

利用电子日记和腕带式加速度计检测慢性阻塞性肺疾病患者的病情加重和活动水平:一项可行性研究

Finney, Lydia J; Avey, Stefan; Wiseman, Dexter; Rowe, Anthony; Loza, Matthew J; Branigan, Patrick; Stevenson, Christopher S; Baribaud, Frédéric; Wedzicha, Jadwiga A; Pandis, Ioannis; Donaldson, Gavin C

Collagen Turnover Biomarkers Associate with Active Psoriatic Arthritis and Decrease with Guselkumab Treatment in a Phase 3 Clinical Trial (DISCOVER-2)

胶原蛋白周转生物标志物与活动性银屑病关节炎相关,并在 3 期临床试验 (DISCOVER-2) 中随着 Guselkumab 治疗而降低

Schett, Georg; Loza, Matthew J; Palanichamy, Arumugam; FitzGerald, Oliver; Ritchlin, Christopher; Bay-Jensen, Anne-Christine; Nielsen, Signe Holm; Gao, Sheng; Hsia, Elizabeth C; Kollmeier, Alexa P; Xu, Xie L; Baribaud, Frédéric; Sweet, Kristen

Publisher Correction to: Collagen Turnover Biomarkers Associate with Active Psoriatic Arthritis and Decrease with Guselkumab Treatment in a Phase 3 Clinical Trial (DISCOVER-2)

出版商更正:胶原蛋白周转生物标志物与活动性银屑病关节炎相关,并在 3 期临床试验 (DISCOVER-2) 中随着 Guselkumab 治疗而降低

Schett, Georg; Loza, Matthew J; Palanichamy, Arumugam; FitzGerald, Oliver; Ritchlin, Christopher; Bay-Jensen, Anne-Christine; Nielsen, Signe Holm; Gao, Sheng; Hsia, Elizabeth C; Kollmeier, Alexa P; Xu, Xie L; Baribaud, Frédéric; Sweet, Kristen

Suppression of Serum Interferon-γ Levels as a Potential Measure of Response to Ustekinumab Treatment in Patients With Systemic Lupus Erythematosus

血清干扰素-γ水平抑制作为系统性红斑狼疮患者对乌司奴单抗治疗反应的潜在指标

Cesaroni, Matteo; Seridi, Loqmane; Loza, Matthew J; Schreiter, Jessica; Sweet, Kristen; Franks, Carol; Ma, Keying; Orillion, Ashley; Campbell, Kim; M Gordon, Robert; Branigan, Patrick; Lipsky, Peter; van Vollenhoven, Ronald; Hahn, Bevra H; Tsokos, George C; Chevrier, Marc; Rose, Shawn; Baribaud, Frédéric; Jordan, Jarrat

Guselkumab induces robust reduction in acute phase proteins and type 17 effector cytokines in active psoriatic arthritis: results from phase 3 trials.

Guselkumab 可显著降低活动性银屑病关节炎中的急性期蛋白和 17 型效应细胞因子:3 期试验结果

Sweet Kristen, Song Qingxuan, Loza Matthew J, McInnes Iain B, Ma Keying, Leander Karen, Lakshminarayanan Vani, Franks Carol, Cooper Philip, Siebert Stefan

I_MDS: an inflammatory bowel disease molecular activity score to classify patients with differing disease-driving pathways and therapeutic response to anti-TNF treatment

I_MDS:一种炎症性肠病分子活性评分,用于对具有不同疾病驱动通路和抗TNF治疗反应的患者进行分类。

Pavlidis, Stelios; Monast, Calixte; Loza, Matthew J; Branigan, Patrick; Chung, Kiang F; Adcock, Ian M; Guo, Yike; Rowe, Anthony; Baribaud, Frédéric

Combined Blockade of TNF-α and IL-17A Alleviates Progression of Collagen-Induced Arthritis without Causing Serious Infections in Mice

联合阻断TNF-α和IL-17A可减轻胶原诱导性关节炎的进展,且不会引起小鼠严重感染

Shen, Fang; Verma, Akash H; Volk, Amy; Jones, Brian; Coleman, Bianca M; Loza, Matthew J; Malaviya, Ravi; Moore, Beverley; Weinstock, Daniel; Elloso, M Merle; Gaffen, Sarah L; Ort, Tatiana

Subcutaneous golimumab for children with active polyarticular-course juvenile idiopathic arthritis: results of a multicentre, double-blind, randomised-withdrawal trial

皮下注射戈利木单抗治疗活动性多关节型幼年特发性关节炎患儿:一项多中心、双盲、随机撤药试验的结果

Brunner, Hermine I; Ruperto, Nicolino; Tzaribachev, Nikolay; Horneff, Gerd; Chasnyk, Vyacheslav G; Panaviene, Violeta; Abud-Mendoza, Carlos; Reiff, Andreas; Alexeeva, Ekaterina; Rubio-Pérez, Nadina; Keltsev, Vladimir; Kingsbury, Daniel J; Del Rocio Maldonado Velázquez, Maria; Nikishina, Irina; Silverman, Earl D; Joos, Rik; Smolewska, Elzbieta; Bandeira, Márcia; Minden, Kirsten; van Royen-Kerkhof, Annet; Emminger, Wolfgang; Foeldvari, Ivan; Lauwerys, Bernard R; Sztajnbok, Flavio; Gilmer, Keith E; Xu, Zhenhua; Leu, Jocelyn H; Kim, Lilianne; Lamberth, Sarah L; Loza, Matthew J; Lovell, Daniel J; Martini, Alberto